Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment

[1]  F. Q. Ribeiro.  The meta-analysis , 2017, Brazilian journal of otorhinolaryngology.

[2]  M. Salemi,et al.  The meningeal lymphatic system: a route for HIV brain migration? , 2016, Journal of NeuroVirology.

[3]  E. Masliah,et al.  Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning , 2016, HIV/AIDS.

[4]  David J. Volsky,et al.  HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment , 2016, Nature Reviews Neurology.

[5]  Trevor Bedford,et al.  Persistent HIV-1 replication maintains the tissue reservoir during therapy , 2015, Nature.

[6]  S. Pacini,et al.  Commentary: Structural and functional features of central nervous system lymphatic vessels , 2015, Front. Neurosci..

[7]  K. Archer,et al.  Gene Expression in HIV-Associated Neurocognitive Disorders: A Meta-Analysis , 2015, Journal of acquired immune deficiency syndromes.

[8]  I. Grant,et al.  Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART , 2015, Scientific Reports.

[9]  J. Ananworanich,et al.  Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naïve HIV-infected Thais , 2015, Journal of Neuroimmunology.

[10]  Michael Detmar,et al.  A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules , 2015 .

[11]  Zhiwei Chen,et al.  Whole genome methylation array reveals the down-regulation of IGFBP6 and SATB2 by HIV-1 , 2015, Scientific Reports.

[12]  S. Horvath,et al.  HIV-1 Infection Accelerates Age According to the Epigenetic Clock , 2015, The Journal of infectious diseases.

[13]  C. Spina,et al.  Cerebrospinal Fluid (CSF) CD8+ T-Cells That Express Interferon-Gamma Contribute to HIV Associated Neurocognitive Disorders (HAND) , 2015, PloS one.

[14]  Zaina Zayyad,et al.  Neuropathogenesis of HIV: From Initial Neuroinvasion to HIV-Associated Neurocognitive Disorder (HAND) , 2015, Current HIV/AIDS Reports.

[15]  E. Ballestar,et al.  Epigenetic control of myeloid cell differentiation, identity and function , 2014, Nature Reviews Immunology.

[16]  D. Kolson,et al.  Neuropathogenesis of HIV-associated neurocognitive disorders: roles for immune activation, HIV blipping and viral tropism , 2014, Current opinion in HIV and AIDS.

[17]  K. Überla,et al.  Cytoplasmic HIV-RNA in monocytes determines microglial activation and neuronal cell death in HIV-associated neurodegeneration , 2014, Experimental Neurology.

[18]  K. Anastos,et al.  CCR2 on CD14+CD16+ monocytes is a biomarker of HIV-associated neurocognitive disorders , 2014, Neurology: Neuroimmunology & Neuroinflammation.

[19]  Richard D Moore,et al.  Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors , 2014, Theranostics.

[20]  Thomas Lengauer,et al.  Comprehensive Analysis of DNA Methylation Data with RnBeads , 2014, Nature Methods.

[21]  M. Katze,et al.  A proteomic glimpse into the initial global epigenetic changes during HIV infection , 2014, Proteomics.

[22]  Nongluk Plongthongkum,et al.  Advances in the profiling of DNA modifications: cytosine methylation and beyond , 2014, Nature Reviews Genetics.

[23]  M. Kaul,et al.  CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-Using HIV-1 Glycoprotein 120 , 2014, The Journal of Immunology.

[24]  J. Ananworanich,et al.  HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy , 2014, AIDS.

[25]  D. Porteous,et al.  Edinburgh Research Explorer Expression of DISC1-Interactome Members Correlates with Cognitive Phenotypes Related to Schizophrenia , 2022 .

[26]  V. Prasad,et al.  Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND) , 2014, AIDS Research and Therapy.

[27]  S. Horvath,et al.  Genetic, Transcriptomic, and Epigenetic Studies of HIV-Associated Neurocognitive Disorder , 2014, Journal of acquired immune deficiency syndromes.

[28]  William P. Accomando,et al.  Quantitative reconstruction of leukocyte subsets using DNA methylation , 2014, Genome Biology.

[29]  R. Irizarry,et al.  Accounting for cellular heterogeneity is critical in epigenome-wide association studies , 2014, Genome Biology.

[30]  S. Horvath,et al.  Transcriptome analysis of HIV-infected peripheral blood monocytes: Gene transcripts and networks associated with neurocognitive functioning , 2013, Journal of Neuroimmunology.

[31]  G. Garden.  Epigenetics and the Modulation of Neuroinflammation , 2013, Neurotherapeutics.

[32]  Kairong Cui,et al.  Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition , 2013, Cell Research.

[33]  R. Ellis,et al.  Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection , 2013, AIDS.

[34]  Edward Y. Chen,et al.  Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.

[35]  P. Singhal,et al.  VDR hypermethylation and HIV‐induced T cell loss , 2013, Journal of leukocyte biology.

[36]  Martin J. Aryee,et al.  A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression , 2013, Epigenetics.

[37]  J. Kere,et al.  Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility , 2012, PloS one.

[38]  A. Oshlack,et al.  SWAN: Subset-quantile Within Array Normalization for Illumina Infinium HumanMethylation450 BeadChips , 2012, Genome Biology.

[39]  K. Williams,et al.  Monocyte Mobilization, Activation Markers, and Unique Macrophage Populations in the Brain: Observations from SIV Infected Monkeys Are Informative with Regard to Pathogenic Mechanisms of HIV Infection in Humans , 2012, Journal of Neuroimmune Pharmacology.

[40]  Peter A. Jones.  Functions of DNA methylation: islands, start sites, gene bodies and beyond , 2012, Nature Reviews Genetics.

[41]  Devin C. Koestler,et al.  DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.

[42]  K. Williams,et al.  Monocyte Mobilization, Activation Markers, and Unique Macrophage Populations in the Brain: Observations from SIV Infected Monkeys Are Informative with Regard to Pathogenic Mechanisms of HIV Infection in Humans , 2011, Journal of Neuroimmune Pharmacology.

[43]  C. Sotiriou,et al.  Evaluation of the Infinium Methylation 450K technology. , 2011, Epigenomics.

[44]  Peter Winter,et al.  SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset. , 2011, Blood.

[45]  I. Grant,et al.  Dopamine receptor D3 genetic polymorphism (rs6280TC) is associated with rates of cognitive impairment in methamphetamine-dependent men with HIV: preliminary findings , 2011, Journal of NeuroVirology.

[46]  Chao Chen,et al.  Down-regulation of HIV-1 infection by inhibition of the MAPK signaling pathway , 2011, Virologica Sinica.

[47]  Daniel Metzger,et al.  The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells , 2011, Nature communications.

[48]  P. Reiss,et al.  HIV-1 infection and cognitive impairment in the cART era: a review. , 2011, AIDS.

[49]  Cory Y. McLean,et al.  GREAT improves functional interpretation of cis-regulatory regions , 2010, Nature Biotechnology.

[50]  M. Kaul,et al.  Open Access Review Molecular Mechanisms of Neuroinvasion by Monocytes-macrophages in Hiv-1 Infection , 2022 .

[51]  M. Allende,et al.  Cystein‐serine‐rich nuclear protein 1, Axud1/Csrnp1, is essential for cephalic neural progenitor proliferation and survival in zebrafish , 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

[52]  E. Rosenberg,et al.  Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection , 2009, Neurology.

[53]  Michele Tinti,et al.  VirusMINT: a viral protein interaction database , 2008, Nucleic Acids Res..

[54]  Tingxi Liu,et al.  Nr4a2 is essential for the differentiation of dopaminergic neurons during zebrafish embryogenesis , 2008, Molecular and Cellular Neuroscience.

[55]  Margaret R. Karagas,et al.  Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions , 2008, BMC Bioinformatics.

[56]  N. Reich,et al.  The early expressed HIV-1 genes regulate DNMT1 expression , 2008, Epigenetics.

[57]  T. Nagasawa,et al.  Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. , 2006, Immunity.

[58]  M. Valenzuela,et al.  Trophic factors in cerebrospinal fluid and spinal cord of patients with tropical spastic paraparesis, HIV, and Creutzfeldt-Jakob disease. , 2006, AIDS research and human retroviruses.

[59]  Tyrone D. Cannon,et al.  Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. , 2005, Archives of general psychiatry.

[60]  O. Selnes,et al.  Higher frequency of dementia in older HIV-1 individuals , 2004, Neurology.

[61]  B. Ward,et al.  Functionally active HLA-G polymorphisms are associated with the risk of heterosexual HIV-1 infection in African women , 2004, AIDS.

[62]  K. Williams,et al.  Monocyte/macrophage traffic in HIV and SIV encephalitis , 2003, Journal of leukocyte biology.

[63]  J. Dausset,et al.  Monocytes and T lymphocytes in HIV-1-positive patients express HLA-G molecule , 2002, AIDS.

[64]  C. H. Chen,et al.  Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients. , 2001, American journal of medical genetics.

[65]  Andreas Hufnagel,et al.  Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART) , 2000, Journal of neurology, neurosurgery, and psychiatry.

[66]  J. McArthur,et al.  Analysis of human immunodeficiency virus type 1 gp160 sequences from a patient with HIV dementia: evidence for monocyte trafficking into brain. , 2000, Journal of neurovirology.

[67]  M. Weinand,et al.  Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. , 1999, The American journal of pathology.

[68]  D. Gabuzda,et al.  ERK MAP Kinase Links Cytokine Signals to Activation of Latent HIV-1 Infection by Stimulating a Cooperative Interaction of AP-1 and NF-κB* , 1999, The Journal of Biological Chemistry.

[69]  J. Becker,et al.  Plasma viral load and CD4 lymphocytes predict HIV-associated dementia and sensory neuropathy , 1999, Neurology.

[70]  J. Berman,et al.  Characterization of monocyte maturation/differentiation that facilitates their transmigration across the blood-brain barrier and infection by HIV: implications for NeuroAIDS. , 2011, Cellular immunology.

[71]  S. Croul,et al.  CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection , 2011, Journal of NeuroVirology.

[72]  Tingxi Liu,et al.  Nr 4 a 2 is essential for the differentiation of dopaminergic neurons during zebra fi sh embryogenesis , 2008 .

[73]  Hong Jiang,et al.  Mutations in NR4A2 associated with familial Parkinson disease , 2003, Nature Genetics.

[74]  J. McArthur,et al.  evidence for monocyte trafficking into brain , 2000 .

[75]  Robert C. Wolpert,et al.  A Review of the , 1985 .