Deep learning and handcrafted feature based approaches for automatic detection of angiectasia

Angiectasia, formerly called angiodysplasia, is one of the most frequent vascular lesions and often the cause of gastrointestinal bleedings. Medical specialists assessing videos or images of examinations reach a detection performance of 16% for the detection of bleeding to 69% for the detection of angiectasia [1]. This shows that automatic detection to support medical experts can be useful. In this paper, we present several machine learning-based approaches for angiectasia detection in wireless video capsule endoscopy frames. In summary, the most promising results for pixel-wise localization and frame-wise detection are obtained by the proposed deep learning method using generative adversarial networks (GANs). Using this approach, we achieve a sensitivity of 88% and specificity of 99.9% for pixel-wise localization, and a sensitivity of 98% and a specificity of 100% for frame-wise detection. Thus, the results demonstrate the capability of using deep learning for automatic angiectasia detection in real clinical settings.

[1]  Michael Riegler,et al.  KVASIR: A Multi-Class Image Dataset for Computer Aided Gastrointestinal Disease Detection , 2017, MMSys.

[2]  Yoshua Bengio,et al.  Generative Adversarial Nets , 2014, NIPS.

[3]  Max Q.-H. Meng,et al.  Computer-Aided Detection of Bleeding Regions for Capsule Endoscopy Images , 2009, IEEE Transactions on Biomedical Engineering.

[4]  Michael Riegler,et al.  CNN and GAN Based Satellite and Social Media Data Fusion for Disaster Detection , 2017, MediaEval.

[5]  Sergey Ioffe,et al.  Rethinking the Inception Architecture for Computer Vision , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[6]  Michael Riegler,et al.  LIRE: open source visual information retrieval , 2016, MMSys.

[7]  Wei Zhang,et al.  Computer-Aided Bleeding Detection in WCE Video , 2014, IEEE Journal of Biomedical and Health Informatics.

[8]  Sang Jun Park,et al.  Retinal Vessel Segmentation in Fundoscopic Images with Generative Adversarial Networks , 2017, ArXiv.

[9]  Jian Sun,et al.  Deep Residual Learning for Image Recognition , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[10]  Khan A. Wahid,et al.  Performance assessment of a bleeding detection algorithm for endoscopic video based on classifier fusion method and exhaustive feature selection , 2018, Biomed. Signal Process. Control..

[11]  K. Geboes,et al.  Vascular lesions of the gastrointestinal tract. , 2002, Acta gastro-enterologica Belgica.

[12]  Neus Guasch,et al.  A comprehensive evaluation of the gastrointestinal tract in iron-deficiency anemia with predefined hemoglobin below 9mg/dL: A prospective cohort study. , 2017, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[13]  Andrew Zisserman,et al.  Very Deep Convolutional Networks for Large-Scale Image Recognition , 2014, ICLR.

[14]  J. Reitsma,et al.  Acute upper GI bleeding: did anything change? , 2003, American Journal of Gastroenterology.

[15]  Geoffrey E. Hinton,et al.  ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.

[16]  Max Q.-H. Meng,et al.  A study on automated segmentation of blood regions in Wireless Capsule Endoscopy images using fully convolutional networks , 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017).

[17]  Max Q.-H. Meng,et al.  Bleeding Frame and Region Detection in the Wireless Capsule Endoscopy Video , 2016, IEEE Journal of Biomedical and Health Informatics.

[18]  Shahed K. Mohammed,et al.  A Saliency-based Unsupervised Method for Angiectasia Detection in Endoscopic Video Frames , 2018 .

[19]  Michael Riegler,et al.  Efficient disease detection in gastrointestinal videos – global features versus neural networks , 2017, Multimedia Tools and Applications.

[20]  Anupam Singh,et al.  Continuing challenges in the diagnosis and management of obscure gastrointestinal bleeding. , 2014, World journal of gastrointestinal pathophysiology.

[21]  Ian H. Witten,et al.  The WEKA data mining software: an update , 2009, SKDD.