Früherkennung und integrierte Versorgung von Jugendlichen und jungen Erwachsenen mit schweren psychotischen Erkrankungen

Zusammenfassung Prospektive 1-Jahres-Follow-up-Untersuchung in der kombinierte multidimensionale Früherkennung und alters- und fachübergreifende integrierte Versorgung (Interventionsbedingung, n = 120) mit einer Standardbehandlung (historische Kontrollgruppe, n = 105) bei Jugendlichen und jungen Erwachsenen in der frühen Phase einer psychotischen Störung verglichen wird. Daten bei Aufnahme in die Studie weisen auf eine hohe Komplexität und Schwere der Erkrankung hin. Primäres Zielkriterium ist die Rate einer 6-monatigen kombiniert symptomatischen und funktionalen Remission zum Studienendpunkt.

[1]  J. Miettunen,et al.  Duration of untreated psychosis as predictor of long-term outcome in schizophrenia: systematic review and meta-analysis , 2014, British Journal of Psychiatry.

[2]  M. Lambert,et al.  [The Hamburg-model of integrated care for patients with psychosis: Part 2. Results of the clinical course over 2- and 4-years of treatment]. , 2014, Psychiatrische Praxis.

[3]  M. Lambert,et al.  [The Hamburg-model of integrated care for patients with psychosis: Part 1. Rationale, treatment concept and results of the pre-study]. , 2014, Psychiatrische Praxis.

[4]  Niall Turner,et al.  First-episode psychosis and disengagement from treatment: a systematic review. , 2014, Psychiatric services.

[5]  M. Menear,et al.  Implementing a Continuum of Evidence-Based Psychosocial Interventions for People with Severe Mental Illness: Part 2—Review of Critical Implementation Issues , 2014, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[6]  M. Menear,et al.  Implementing a Continuum of Evidence-Based Psychosocial Interventions for People with Severe Mental Illness: Part 1—Review of Major Initiatives and Implementation Strategies , 2014, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[7]  D. Streiner,et al.  Risk of symptom recurrence with medication discontinuation in first-episode psychosis: A systematic review , 2014, Schizophrenia Research.

[8]  U. Malm,et al.  Resource Group Assertive Community Treatment (RACT) as a Tool of Empowerment for Clients with Severe Mental Illness: A Meta-Analysis , 2012, Clinical practice and epidemiology in mental health : CP & EMH.

[9]  B. Löwe,et al.  Rationale and content of psychenet: the Hamburg Network for Mental Health , 2012, European Archives of Psychiatry and Clinical Neuroscience.

[10]  R. Emsley,et al.  Treatment response after relapse in a placebo-controlled maintenance trial in schizophrenia , 2012, Schizophrenia Research.

[11]  J. Tiihonen,et al.  A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia. , 2011, The American journal of psychiatry.

[12]  S. Pilling,et al.  Initiatives to shorten duration of untreated psychosis: systematic review , 2011, British Journal of Psychiatry.

[13]  G. Krarup,et al.  Predictors of recovery from psychosis Analyses of clinical and social factors associated with recovery among patients with first-episode psychosis after 5years , 2011, Schizophrenia Research.

[14]  L. Siegel,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2008 .

[15]  Peter B. Jones,et al.  Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review. , 2005, Archives of general psychiatry.

[16]  Jeffrey A. Lieberman,et al.  International clinical practice guidelines for early psychosis , 2005, British Journal of Psychiatry.

[17]  D. Weinberger,et al.  Remission in schizophrenia: proposed criteria and rationale for consensus. , 2005, The American journal of psychiatry.

[18]  M. Ruggeri,et al.  Definition and prevalence of severe and persistent mental illness , 2000, British Journal of Psychiatry.

[19]  M. Marshall,et al.  Assertive community treatment for people with severe mental disorders. , 2000, The Cochrane database of systematic reviews.

[20]  R Giel,et al.  Natural course of schizophrenic disorders: a 15-year followup of a Dutch incidence cohort. , 1998, Schizophrenia bulletin.