Doubly heavy systems: decays and OPE

We discuss questions related to the application of OPE for the long-lived systems with two heavy flavors. The values of quark masses entering such calulations are constrained by use of currently available data on the lifetimes of $B_d$ and $B_c$-mesons. The lifetimes of doubly charmed baryons at these values of parameters are evaluated. The necessary comments on the difference in the results obtained previously are made.