Diagnostic lobectomy is not routinely required to exclude malignancy in thyroid nodules greater than four centimetres

Background:  Surgical excision has been recommended as a diagnostic test for thyroid nodules ≥4 cm, due to the supposedly higher rate of cancer in larger nodules and the higher reported false‐negative rates of fine‐needle aspiration cytology (FNAC) testing (>10%). The aims of this study are to determine the prevalence of thyroid cancer in nodules ≥4 cm, to examine if a relationship between increasing nodule size and malignancy rate was present and to study the accuracy of preoperative FNAC diagnosis.

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