Nucleostemin exerts anti-apoptotic function via p53 signaling pathway in cardiomyocytes

[1]  N. Hariharan,et al.  Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging. , 2015, Journal of the American College of Cardiology.

[2]  Z. Serdar,et al.  Effective inhibition of cardiomyocyte apoptosis through the combination of trimetazidine and N-acetylcysteine in a rat model of myocardial ischemia and reperfusion injury. , 2014, Atherosclerosis.

[3]  H. Nakayama,et al.  Overexpression of nucleostemin contributes to an advanced malignant phenotype and a poor prognosis in oral squamous cell carcinoma , 2014, British Journal of Cancer.

[4]  V. Budhram-Mahadeo,et al.  Co-expression of POU4F2/Brn-3b with p53 may be important for controlling expression of pro-apoptotic genes in cardiomyocytes following ischaemic/hypoxic insults , 2014, Cell Death and Disease.

[5]  L. Pitto,et al.  Triiodothyronine prevents cardiac ischemia/reperfusion mitochondrial impairment and cell loss by regulating miR30a/p53 axis. , 2014, Endocrinology.

[6]  W. Guan,et al.  In vitro study of nucleostemin as a potential therapeutic target in human breast carcinoma SKBR-3 cells. , 2014, Asian Pacific journal of cancer prevention : APJCP.

[7]  Jichun Liu,et al.  Notch signaling activation contributes to cardioprotection provided by ischemic preconditioning and postconditioning , 2013, Journal of Translational Medicine.

[8]  Yajing Wang,et al.  C1q/Tumor Necrosis Factor–Related Protein-9, a Novel Adipocyte-Derived Cytokine, Attenuates Adverse Remodeling in the Ischemic Mouse Heart via Protein Kinase A Activation , 2013, Circulation.

[9]  Hongwei Wang,et al.  Ginsenoside RK3 Prevents Hypoxia-Reoxygenation Induced Apoptosis in H9c2 Cardiomyocytes via AKT and MAPK Pathway , 2013, Evidence-based complementary and alternative medicine : eCAM.

[10]  G. Peng,et al.  Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells , 2013, Proceedings of the National Academy of Sciences.

[11]  T. Minamino.  Cardioprotection from ischemia/reperfusion injury: basic and translational research. , 2012, Circulation journal : official journal of the Japanese Circulation Society.

[12]  T. Minamino.  Cardioprotection From Ischemia/Reperfusion Injury , 2012 .

[13]  Y. Okazaki,et al.  Differential Requirement for Nucleostemin in Embryonic Stem Cell and Neural Stem Cell Viability , 2009, Stem cells.

[14]  Mark A Sussman,et al.  Myocardial Induction of Nucleostemin in Response to Postnatal Growth and Pathological Challenge , 2008, Circulation research.

[15]  S. Dimmeler,et al.  A nucleolar weapon in our fight for regenerating adult hearts: nucleostemin and cardiac stem cells. , 2008, Circulation research.

[16]  Mark A Sussman,et al.  Activation of Notch-Mediated Protective Signaling in the Myocardium , 2008, Circulation research.

[17]  Yuer Zhang,et al.  Expression of nucleostemin in prostate cancer and its effect on the proliferation of PC-3 cells. , 2008, Chinese medical journal.

[18]  Jeffrey Robbins,et al.  Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury , 2007, Nature Medicine.

[19]  W. Wurst,et al.  Evolutionarily Conserved Role of Nucleostemin: Controlling Proliferation of Stem/Progenitor Cells during Early Vertebrate Development , 2006, Molecular and Cellular Biology.

[20]  P. Ekman,et al.  Nucleostemin mRNA is expressed in both normal and malignant renal tissues , 2006, British Journal of Cancer.

[21]  R. Bolli,et al.  Myocardial Protection at a Crossroads: The Need for Translation Into Clinical Therapy , 2004, Circulation research.

[22]  R. McKay,et al.  A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. , 2002, Genes & development.

[23]  G. Biondi-Zoccai,et al.  Pathophysiologic role of myocardial apoptosis in post‐infarction left ventricular remodeling , 2002, Journal of cellular physiology.

[24]  T. Koyama,et al.  Upregulation of P53 protein in rat heart subjected to a transient occlusion of the coronary artery followed by reperfusion. , 2000, The Japanese journal of physiology.

[25]  N. Maulik,et al.  Ischemic preconditioning reduces apoptosis by upregulating anti-death gene Bcl-2. , 1999, Circulation.

[26]  E. Lakatta,et al.  p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes. , 1997, The Journal of clinical investigation.

[27]  P. Anversa,et al.  Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. , 1996, Journal of molecular and cellular cardiology.

[28]  E. Braunwald,et al.  Myocardial reperfusion: a double-edged sword? , 1985, The Journal of clinical investigation.

[29]  A. Ibrahim,et al.  Acute myocardial infarction. , 2014, Critical care clinics.

[30]  Xiuhua Liu,et al.  MicroRNA-15b enhances hypoxia/reoxygenation-induced apoptosis of cardiomyocytes via a mitochondrial apoptotic pathway , 2013, Apoptosis.

[31]  L. Becker.  Myocardial Reperfusion Injury , 2004, Journal of Thrombosis and Thrombolysis.

[32]  John Calvin Reed,et al.  Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. , 1996, Laboratory investigation; a journal of technical methods and pathology.