Fluorescent Double Labeling Studies of Thalamostriatal and Corticostriatal Neurons

For many years, one of most intriguing questions in neuroanatomy concerned the hodological relationships between the striatum (caudate nucleus and putamen), the thalamus, and the cerebral cortex. While degeneration methods had readily demonstrated that most thalamic nuclei project to the cortex, other thalamic nuclei, particularly those with connections to the striatum, appeared to lack cortical connections.

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