Automatic detection of graticule isocenter and scale from kV and MV images

Abstract Purpose To automate the detection of isocenter and scale of the mechanical graticule on kilo‐voltage (kV) or mega‐voltage (MV) films or electronic portal imaging device (EPID) images. Methods We developed a robust image processing approach to automatically detect isocenter and scale of mechanical graticule from digitized kV or MV films and EPID images. After a series of preprocessing steps applied to the digital images, a combination of Hough transform and Radon transform was performed to detect the graticule axes and isocenter. The magnification of the graticule was automatically detected by solving an optimization problem using golden section search and parabolic interpolation algorithm. Tick marks of the graticule were then determined by extending from isocenter along the graticule axes with multiples of the magnification value. This approach was validated using 23 kV films, 26 MV films, and 91 EPID images in different anatomical sites (head‐and‐neck, thorax, and pelvis). Accuracy was measured by comparing computer detected results with manually selected results. Results The proposed approach was robust for kV and MV films of varying image quality. The isocenter was detected within 1 mm for 98% of the images. The exceptions were three kV films where the graticule was not actually visible. Of all images with correct isocenter detection, 99% had a magnification detection error less than 1% and tick mark detection error less than 1 mm, with the exception of 1 kV film (magnification error: 3.17%; tick mark error: 1.29 mm) and 1 MV film (magnification error: 0.45%; tick mark error: 1.11 mm). Conclusion We developed an approach to robustly and automatically detect graticule isocenter and scale from two‐dimensionla (2D) kV and MV films. This is a first step toward automated treatment planning based on 2D x‐ray images.

[1]  Peter Balter,et al.  Model for Estimating Power and Downtime Effects on Teletherapy Units in Low-Resource Settings , 2017, Journal of global oncology.

[2]  Sridhar Yaddanapudi,et al.  Automated radiation therapy treatment plan workflow using a commercial application programming interface. , 2014, Practical radiation oncology.

[3]  L. Gaspar,et al.  Radiotherapeutic Management of Non–Small Cell Lung Cancer in the Minimal Resource Setting , 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[4]  Jinzhong Yang,et al.  Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System , 2018, Journal of visualized experiments : JoVE.

[5]  Roberto Brunelli,et al.  Template Matching Techniques in Computer Vision: Theory and Practice , 2009 .

[6]  Practical quantitative measurement of graticule misalignment relative to collimator axis of rotation , 2010, Journal of applied clinical medical physics.

[7]  R. J. Barish,et al.  Radiation Oncology Physics: A Handbook for Teachers and Students , 2006 .

[8]  Luc Van Gool,et al.  Efficient Non-Maximum Suppression , 2006, 18th International Conference on Pattern Recognition (ICPR'06).

[9]  M. Frommer,et al.  Role of radiotherapy in cancer control in low-income and middle-income countries. , 2006, The Lancet. Oncology.

[10]  J. P. Lewis Fast Normalized Cross-Correlation , 2010 .

[11]  Michael A. Malcolm,et al.  Computer methods for mathematical computations , 1977 .

[12]  Yolande Lievens,et al.  Cost evaluation to optimise radiation therapy implementation in different income settings: A time-driven activity-based analysis. , 2017, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[13]  James Yang,et al.  A robust Hough transform algorithm for determining the radiation centers of circular and rectangular fields with subpixel accuracy. , 2009, Physics in medicine and biology.

[14]  N. Datta,et al.  Radiation therapy infrastructure and human resources in low- and middle-income countries: present status and projections for 2020. , 2014, International journal of radiation oncology, biology, physics.

[15]  P. Munro,et al.  Clinical use of electronic portal imaging: report of AAPM Radiation Therapy Committee Task Group 58. , 2001, Medical physics.

[16]  Peter B. Greer,et al.  Isocenter verification for linac‐based stereotactic radiation therapy: review of principles and techniques , 2011, Journal of applied clinical medical physics.

[17]  Sarah Eichmann,et al.  The Radon Transform And Some Of Its Applications , 2016 .

[18]  A. Mundt,et al.  Radiation oncology in Africa: improving access to cancer care on the African continent. , 2014, International journal of radiation oncology, biology, physics.

[19]  Lei Dong,et al.  Advantages of simulating thoracic cancer patients in an upright position. , 2014, Practical radiation oncology.

[20]  N. Mutrikah,et al.  Conventional and conformal technique of external beam radiotherapy in locally advanced cervical cancer: Dose distribution, tumor response, and side effects , 2017 .

[21]  Roberto Brunelli,et al.  Advanced , 1980 .

[22]  Weiliang Du,et al.  A simple method to quantify the coincidence between portal image graticules and radiation field centers or radiation isocenter. , 2010, Medical physics.

[23]  Isaac I. Rosen,et al.  Evaluation of a commercial flatbed document scanner and radiographic film scanner for radiochromic EBT film dosimetry , 2010, Journal of applied clinical medical physics.

[24]  Fang-Fang Yin,et al.  Task Group 142 report: quality assurance of medical accelerators. , 2009, Medical physics.

[25]  D. Jaffray,et al.  Bringing global access to radiation therapy: time for a change in approach. , 2014, International journal of radiation oncology, biology, physics.

[26]  C. Badri,et al.  Multinational assessment of some operational costs of teletherapy. , 2004, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.