Inhibition of sonic hedgehog signaling via MAPK activation controls chemotherapy-induced alopecia.
暂无分享,去创建一个
Guojiang Xie | R. Paus | Zhicao Yue | Xiulan Ao | Yanding Zhang | J. Wierzbicka | X. Teng | GuiXuan Zhou | Zhipeng Yan | I. Haslam | Zhen Huang | N. Farjo | B. Farjo | E. Smart | Yongjian Zhou | D. Rutkowski | XiuLan Ao
[1] W. Banlunara,et al. Increasing the percutaneous absorption and follicular penetration of retinal by topical application of proretinal nanoparticles , 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[2] M. Lacouture,et al. Hair disorders in cancer survivors. , 2019, Journal of the American Academy of Dermatology.
[3] M. Lacouture,et al. Hair disorders in patients with cancer. , 2019, Journal of the American Academy of Dermatology.
[4] Sung-Jan Lin,et al. How chemotherapy and radiotherapy damage the tissue: Comparative biology lessons from feather and hair models , 2018, Experimental dermatology.
[5] X. Lim,et al. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles , 2018, PLoS biology.
[6] M. Lacouture,et al. Scalp hypothermia as a preventative measure for chemotherapy‐induced alopecia: a review of controlled clinical trials , 2018, Journal of the European Academy of Dermatology and Venereology : JEADV.
[7] Sung-Jan Lin,et al. Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy. , 2017, Cancer research.
[8] F. F. Sahle,et al. Synthesis and Validation of Functional Nanogels as pH-Sensors in the Hair Follicle. , 2017, Macromolecular bioscience.
[9] C. Antoniou,et al. From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dots , 2017, The British journal of dermatology.
[10] W. Huber,et al. The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances , 2016, Developmental cell.
[11] X. Li,et al. Disturbed MEK/ERK signaling increases osteoclast activity via the Hedgehog-Gli pathway in postmenopausal osteoporosis. , 2016, Progress in biophysics and molecular biology.
[12] Y. Hsu,et al. Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog , 2016, Genes & development.
[13] O. Kwon,et al. Development of a Model for Chemotherapy-Induced Alopecia: Profiling of Histological Changes in Human Hair Follicles after Chemotherapy. , 2016, The Journal of investigative dermatology.
[14] M. Lacouture,et al. Alopecia in patients treated with molecularly targeted anticancer therapies. , 2015, Annals of oncology : official journal of the European Society for Medical Oncology.
[15] R. Paus,et al. Human hair follicle organ culture: theory, application and perspectives , 2015, Experimental dermatology.
[16] N. Farber,et al. Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis , 2015, Neurobiology of Disease.
[17] L. Vahdat,et al. Efficacy of Scalp Cooling in Preventing Chemotherapy-Induced Alopecia in Breast Cancer Patients Receiving Adjuvant Docetaxel and Cyclophosphamide Chemotherapy. , 2015, Clinical breast cancer.
[18] Guojiang Xie,et al. Testing chemotherapeutic agents in the feather follicle identifies a selective blockade of cell proliferation and a key role for sonic hedgehog signaling in chemotherapy-induced tissue damage. , 2015, The Journal of investigative dermatology.
[19] L. Lettice,et al. Mapping the Shh long-range regulatory domain , 2014, Development.
[20] A. Joyner,et al. Roles for Hedgehog signaling in adult organ homeostasis and repair , 2014, Development.
[21] H. Roe. Scalp cooling: management option for chemotherapy-induced alopecia. , 2014, British journal of nursing.
[22] J. Spiegel,et al. Complex changes in the apoptotic and cell differentiation programs during initiation of the hair follicle response to chemotherapy , 2014, The Journal of investigative dermatology.
[23] S. Lee,et al. Cyclopamine: from cyclops lambs to cancer treatment. , 2014, Journal of agricultural and food chemistry.
[24] Xiaohu Zhang,et al. Cyclopamine, a naturally occurring alkaloid, and its analogues may find wide applications in cancer therapy. , 2013, Current topics in medicinal chemistry.
[25] P. Watson,et al. Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia , 2013, PloS one.
[26] H. H. Ryu,et al. Pretreatment of epidermal growth factor promotes primary hair recovery via the dystrophic anagen pathway after chemotherapy‐induced alopecia , 2013, Experimental dermatology.
[27] Ralf Paus,et al. Pathobiology of chemotherapy-induced hair loss. , 2013, The Lancet. Oncology.
[28] Benjamin D. Yu,et al. Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. , 2013, Developmental biology.
[29] H. Zhen,et al. Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop. , 2012, Genes & development.
[30] A. Joyner,et al. Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells. , 2011, Cell stem cell.
[31] V. Rotter,et al. p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss , 2010, FEBS letters.
[32] J. Blenis,et al. ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events. , 2010, Molecular cell.
[33] R. Paus,et al. Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture , 2010, Experimental dermatology.
[34] C. Tabin,et al. Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. , 2009, Developmental cell.
[35] D. Tobin,et al. Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy. , 2007, The American journal of pathology.
[36] T. Schlake,et al. Localization of Shh expression by Wnt and Eda affects axial polarity and shape of hairs. , 2007, Developmental biology.
[37] B. Ducommun,et al. Identification of an unexpected link between the Shh pathway and a G2/M regulator, the phosphatase CDC25B. , 2006, Developmental biology.
[38] B. Morgan,et al. Distinct stem cell populations regenerate the follicle and interfollicular epidermis. , 2005, Developmental cell.
[39] C. Hui,et al. Shh controls epithelial proliferation via independent pathways that converge on N-Myc. , 2005, Developmental cell.
[40] J. Blenis,et al. Spatially Separate Docking Sites on ERK2 Regulate Distinct Signaling Events In Vivo , 2005, Current Biology.
[41] R. Paus,et al. A guide to assessing damage response pathways of the hair follicle: lessons from cyclophosphamide-induced alopecia in mice. , 2005, The Journal of investigative dermatology.
[42] B. Gilchrest,et al. Fas Signaling Is Involved in the Control of Hair Follicle Response to Chemotherapy , 2004, Cancer Research.
[43] Robert J. Wechsler-Reya,et al. Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[44] C. Hui,et al. Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. , 2003, Genes & development.
[45] Michael D. Cole,et al. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors , 2003, Development.
[46] R. Crystal,et al. Effect of adenovirus-mediated expression of Sonic hedgehog gene on hair regrowth in mice with chemotherapy-induced alopecia. , 2001, Journal of the National Cancer Institute.
[47] B. Gilchrest,et al. p53 is essential for chemotherapy-induced hair loss. , 2000, Cancer research.
[48] Y. Barrandon,et al. Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration , 2000 .
[49] R. Paus,et al. Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia. , 2000, The American journal of pathology.
[50] M V Chernov,et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. , 1999, Science.
[51] D. Tobin,et al. Do hair bulb melanocytes undergo apoptosis during hair follicle regression (catagen)? , 1998, The Journal of investigative dermatology.
[52] R. Paus,et al. Reduction of intrafollicular apoptosis in chemotherapy-induced alopecia by topical calcitriol-analogs. , 1998, The Journal of investigative dermatology.
[53] R. Paus,et al. Sonic hedgehog signaling is essential for hair development , 1998, Current Biology.
[54] Carina,et al. Analysis of apoptosis during hair follicle regression (catagen) , 1997, The American journal of pathology.
[55] S. Eichmüller,et al. Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone. , 1994, The American journal of pathology.
[56] A. Collett,et al. A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention. , 2018, The oncologist.
[57] V. Garelli,et al. ON Chemotherapy-induced alopecia management : Clinical experience and practical advice , 2017 .
[58] B. Gilchrest,et al. p53 Involvement in the control of murine hair follicle regression. , 2001, The American journal of pathology.
[59] W Gaffield,et al. Essential role for Sonic hedgehog during hair follicle morphogenesis. , 1999, Developmental biology.