Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model

[1]  Wenlin Huang,et al.  The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells , 2017, Chinese journal of cancer.

[2]  P. Tsai,et al.  Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues , 2016, PloS one.

[3]  E. Nestler,et al.  Epigenetic Basis of Mental Illness , 2016, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[4]  Daniel R Weinberger,et al.  Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study. , 2016, JAMA psychiatry.

[5]  J. Smoller,et al.  Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways , 2016, Molecular Psychiatry.

[6]  M. Wong,et al.  Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition , 2015, Molecular Psychiatry.

[7]  J. Hettema,et al.  Genetics of anxiety disorders: Genetic epidemiological and molecular studies in humans , 2015, Psychiatry and clinical neurosciences.

[8]  Elisabeth B. Binder,et al.  Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions , 2015, Neuron.

[9]  N. Mullins,et al.  Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes , 2015, Psychiatric genetics.

[10]  D. Hernandez,et al.  DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels , 2015, Circulation. Cardiovascular genetics.

[11]  D. Agrawal,et al.  Methylation and microRNA-mediated epigenetic regulation of SOCS3 , 2015, Molecular Biology Reports.

[12]  Heidi Combs,et al.  Anxiety disorders in primary care. , 2014, The Medical clinics of North America.

[13]  C. Beard,et al.  Beyond generalized anxiety disorder: psychometric properties of the GAD-7 in a heterogeneous psychiatric sample. , 2014, Journal of anxiety disorders.

[14]  K. Hansen,et al.  Functional normalization of 450k methylation array data improves replication in large cancer studies , 2014, Genome Biology.

[15]  M. Irwin,et al.  From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. , 2014, Psychological bulletin.

[16]  M. L. Nielsen,et al.  Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase* , 2013, The Journal of Biological Chemistry.

[17]  M. Esler,et al.  Methylation of the SLC6a2 Gene Promoter in Major Depression and Panic Disorder , 2013, PloS one.

[18]  Brenda,et al.  Association of Subclinical Inflammation With Polyneuropathy in the Older Population , 2013, Diabetes Care.

[19]  C. Baldwin,et al.  The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity , 2013, Psychoneuroendocrinology.

[20]  Monique Ernst,et al.  Response to learned threat: An FMRI study in adolescent and adult anxiety. , 2013, The American journal of psychiatry.

[21]  Álvaro Camacho.  Is anxious-depression an inflammatory state? , 2013, Medical hypotheses.

[22]  F. von Delft,et al.  Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases , 2013, Journal of molecular biology.

[23]  Christian Gieger,et al.  Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation , 2013, PloS one.

[24]  Mathias V. Schmidt,et al.  Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss , 2013, Nature Neuroscience.

[25]  B. Bradley,et al.  Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions , 2012, Nature Neuroscience.

[26]  T. Petryshen,et al.  Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology , 2012, Biology of Mood & Anxiety Disorders.

[27]  F. McMahon,et al.  Replication and meta-analysis of TMEM132D gene variants in panic disorder , 2012, Translational Psychiatry.

[28]  Abdulrahman M El-Sayed,et al.  Epigenetic modifications associated with suicide and common mood and anxiety disorders: a systematic review of the literature , 2012, Biology of Mood & Anxiety Disorders.

[29]  William P. Accomando,et al.  DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.

[30]  N. Wray,et al.  Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes , 2012, European Journal of Human Genetics.

[31]  Evan T. Geller,et al.  Patterns and rates of exonic de novo mutations in autism spectrum disorders , 2012, Nature.

[32]  B. Bradley,et al.  Differential immune system DNA methylation and cytokine regulation in post‐traumatic stress disorder , 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[33]  S. Cichon,et al.  TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies , 2011, Molecular Psychiatry.

[34]  T. Maurice,et al.  Behavioural phenotyping of knockout mice for the sigma-1 (σ1) chaperone protein revealed gender-related anxiety, depressive-like and memory alterations , 2011, Journal of psychopharmacology.

[35]  Xiao Zhang,et al.  Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis , 2010, BMC Bioinformatics.

[36]  S. Galea,et al.  Epigenetic and immune function profiles associated with posttraumatic stress disorder , 2010, Proceedings of the National Academy of Sciences.

[37]  Brian W. Haas,et al.  Emotional memory function, personality structure and psychopathology: A neural system approach to the identification of vulnerability markers , 2007, Brain Research Reviews.

[38]  Patrick Monahan,et al.  Anxiety Disorders in Primary Care: Prevalence, Impairment, Comorbidity, and Detection , 2007, Annals of Internal Medicine.

[39]  B. Löwe,et al.  A brief measure for assessing generalized anxiety disorder: the GAD-7. , 2006, Archives of internal medicine.

[40]  R Holle,et al.  KORA - A Research Platform for Population Based Health Research , 2005, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

[41]  C. Gieger,et al.  KORA-gen - Resource for Population Genetics, Controls and a Broad Spectrum of Disease Phenotypes , 2005 .

[42]  J. Albina,et al.  Ankyrin Repeat and SOCS Box 3 (ASB3) Mediates Ubiquitination and Degradation of Tumor Necrosis Factor Receptor II , 2005, Molecular and Cellular Biology.

[43]  J. Johnston,et al.  SOCS: role in inflammation, allergy and homeostasis. , 2004, Trends in immunology.

[44]  C. Gale,et al.  Generalised anxiety disorder , 2004, Clinical evidence.

[45]  Christian C Witt,et al.  The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. , 2003, Journal of molecular biology.

[46]  D. Hilton,et al.  SOCS Proteins: Negative Regulators of Cytokine Signaling , 2001, Stem cells.

[47]  W. Alexander,et al.  Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction , 1999, Journal of leukocyte biology.

[48]  B. Bandelow,et al.  Assessing the efficacy of treatments for panic disorder and agoraphobia. II. The Panic and Agoraphobia Scale , 1995, International clinical psychopharmacology.

[49]  E. Rüther,et al.  Assessing the efficacy of treatments for panic disorder and agoraphobia. I. Methodological problems , 1995, International clinical psychopharmacology.

[50]  R. Kessler,et al.  The structure of the genetic and environmental risk factors for six major psychiatric disorders in women. Phobia, generalized anxiety disorder, panic disorder, bulimia, major depression, and alcoholism. , 1995, Archives of general psychiatry.

[51]  K. Ressler,et al.  Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond , 2017, Neuropsychopharmacology.

[52]  A. Hariri,et al.  A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety through Increased Threat-Related Amygdala Reactivity in Women but Not Men , 2017, Neuropsychopharmacology.

[53]  Jordan W Smoller,et al.  The Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety Disorders , 2016, Neuropsychopharmacology.

[54]  E. Binder,et al.  Gene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications , 2016, Neuropsychopharmacology.

[55]  F. Guimarães,et al.  Animal models of anxiety disorders and stress. , 2013, Revista brasileira de psiquiatria.

[56]  D. Pine,et al.  Incidence and risk patterns of anxiety and depressive disorders and categorization of generalized anxiety disorder. , 2010, Archives of general psychiatry.

[57]  M. Longaker,et al.  Original Research Article , 2004 .

[58]  Hans-Ulrich Wittchen,et al.  DIA-X-Interviews: Manual für Screening-Verfahren und Interview; Interviewheft , 1997 .

[59]  C. Coulson,et al.  Molecular Architecture , 1953, Nature.