Between prediction, education, and quality control: simulation models in critical care

Today, computer-aided strategies in social sciences are an indispensable component of teaching programs. In recent years, microsimulation modeling has gained attention in its ability to represent predicted physiological developments visually, thus providing the user with a full understanding of the impacts of a proposed scheme. There are several microsimulation models in human medicine, and they can be either dynamic or static. If the model is dynamic the course of variables changes over time; in contrast, in the static case time constancy is assumed. In critical care there have been several approaches to implement microsimulation models to predict outcome. This commentary describes current approaches for predicting disease progression by using dynamic microsimulation in pneumonia-related sepsis.