Use of a Temperature Gradient Measuring Device in Monitoring of Diabetic and Critically Ill Patients

A device realizing the simultaneous measure of the central body temperature (Tc), the superficial one (Ts) and their difference (Dt), was proposed for permanent energetic balance evaluation in humans. A program was elaborated to command the intravenous delivery of insulin by a pump depending on the value and trends of Dt. The use of this device for monitoring of decompensated diabetic patients allowed their easier stabilization. In critically ill patients (post transplantation, myocardium infarction) it had a diagnostic and prognostic value, and was helpful for optimization of conventional and insulin therapy.

[1]  P. Cryer Hypoglycemia: The Limiting Factor in the Management of IDDM , 1994, Diabetes.

[2]  Daisuke Kokuryo,et al.  Near-real-time feedback control system for liver thermal ablations based on self-referenced temperature imaging. , 2006, European journal of radiology.

[3]  M. Matsuda,et al.  Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin , 2005, Science.

[4]  Gary W. Dorshimer,et al.  Core temperature and percentage of dehydration in professional football linemen and backs during preseason practices. , 2006, Journal of athletic training.

[5]  M. Matsuda,et al.  Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. , 2005, Science.

[6]  R. Ogawa,et al.  Patients with Diabetic Neuropathy Are at Risk of a Greater Intraoperative Reduction in Core Temperature , 2000, Anesthesiology.

[7]  Cryer Pe Banting Lecture. Hypoglycemia: the limiting factor in the management of IDDM. , 1994 .

[8]  P. Amarenco,et al.  [Hyperglycemia: a predictor of poor prognosis in acute stroke]. , 2001, Diabetes & metabolism.

[9]  P Stauffer,et al.  Non-invasive temperature profile estimation in a lossy medium based on multi-band radiometric signals sensed by a microwave dual-purpose body-contacting antenna , 2002, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[10]  F. Visser,et al.  Insulin: a wonder drug in the critically ill? , 2002, Critical care.

[11]  H. Yoshimatsu,et al.  Impaired response of UCP family to cold exposure in diabetic (db/db) mice. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

[12]  G. Delhomme,et al.  Wearable Medical Devices Using Textile and Flexible Technologies for Ambulatory Monitoring , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[13]  M Schetz,et al.  Intensive insulin therapy in critically ill patients. , 2001, The New England journal of medicine.

[14]  Y. Aso,et al.  Thermographic measurement of skin temperature recovery time of extremities in patients with type 2 diabetes mellitus. , 2000, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[15]  L. Fleisher,et al.  Core Hypothermia and Skin‐surface Temperature Gradients: Epidural Versus General Anesthesia and the Effects of Age , 1994, Anesthesiology.

[16]  B. Bocquet,et al.  Microwave radiometry for non-invasive thermometry , 1987 .

[17]  A. Sadaniantz Glucose-insulin-potassium use in acute myocardial infarction. , 1999, Circulation.

[18]  V. A. Simonov,et al.  Electronic quartz device for control of the energetic balance in man and animals (appliance in diabetes mellitus) , 1992, Annual International Conference of the IEEE Engineering in Medicine and Biology Society.