CLINICAL EXPERIENCES WITH 1,1,1 TRICHLOROETHANE: a preliminary report of 50 Anesthetic Administrations

Recently, Krantz and co-workersl did a laboratory investigation of the anesthetic properties of another noninflammable halogenated hydrocarbon, 1,1,1 trichloroethane. They used dogs and rhesus monkeys and found that inhalation anesthesia could be produced rapidly, respirations were deep, salivary and bronchial secretions were minimal, and “relaxation of the abdominal area and extremities was good.” Recovery from anesthesia was rapid and tranquil, and “analgesia appeared to extend well into the recovery period.”l During 1958 we initiated a clinical trial of the compound and as of April, 1959, have administered i t to over 50 patients undergoing operative procedures at the John Gaston Hospital. This report summarizes our observations in 50 of these administrations.