The synergy of diammonium glycyrrhizinate remarkably reduces the toxicity of oxymatrine in ICR mice.

[1]  F. Gonzalez,et al.  Glycyrrhizin and glycyrrhetinic acid inhibits alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption. , 2017, Toxicology.

[2]  Guangji Wang,et al.  Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis , 2016, Drug Metabolism and Disposition.

[3]  Runyue Huang,et al.  Can active components of licorice, glycyrrhizin and glycyrrhetinic acid, lick rheumatoid arthritis? , 2015, Oncotarget.

[4]  P. Chanvorachote,et al.  Glycyrrhizic acid attenuates stem cell-like phenotypes of human dermal papilla cells. , 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[5]  Jian-Qiang Yu,et al.  Oxymatrine attenuated hypoxic-ischemic brain damage in neonatal rats via improving antioxidant enzyme activities and inhibiting cell death , 2015, Neurochemistry International.

[6]  A. Viera,et al.  Potassium Disorders: Hypokalemia and Hyperkalemia. , 2015, American family physician.

[7]  S. Kao,et al.  Glycyrrhizin, silymarin, and ursodeoxycholic acid regulate a common hepatoprotective pathway in HepG2 cells. , 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[8]  Shuai Ji,et al.  Separation and characterization of phenolic compounds and triterpenoid saponins in licorice (Glycyrrhiza uralensis) using mobile phase-dependent reversed-phase×reversed-phase comprehensive two-dimensional liquid chromatography coupled with mass spectrometry. , 2015, Journal of chromatography. A.

[9]  Guo‐Hua Huang,et al.  Anti-tumor activities of active ingredients in Compound Kushen Injection , 2015, Acta Pharmacologica Sinica.

[10]  Linna Liu,et al.  Investigating herb-herb interactions: the potential attenuated toxicity mechanism of the combined use of Glycyrrhizae radix et rhizoma (Gancao) and Sophorae flavescentis radix (Kushen). , 2015, Journal of ethnopharmacology.

[11]  G. Tan,et al.  Glycyrrhizin Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in BALB/c Mice and Inhibits TNF-a-Induced ICAM-1 Expression via NF-κB/MAPK in HaCaT Cells , 2015, Cellular Physiology and Biochemistry.

[12]  Xiaoquan Liu,et al.  A Semi-Physiologically Based Pharmacokinetic Pharmacodynamic Model for Glycyrrhizin-Induced Pseudoaldosteronism and Prediction of the Dose Limit Causing Hypokalemia in a Virtual Elderly Population , 2014, PloS one.

[13]  Ling Gao,et al.  The Protective Effect of Glycyrrhizic Acid on Renal Tubular Epithelial Cell Injury Induced by High Glucose , 2014, International journal of molecular sciences.

[14]  Naisheng Zhang,et al.  Oxymatrine Lightened the Inflammatory Response of LPS-Induced Mastitis in Mice Through Affecting NF-κB and MAPKs Signaling Pathways , 2014, Inflammation.

[15]  Bo Zhang,et al.  Oxymatrine prevents hypoxia- and monocrotaline-induced pulmonary hypertension in rats. , 2014, Free radical biology & medicine.

[16]  Xiaoya Li,et al.  Anti-tumor activities of matrine and oxymatrine: literature review , 2014, Tumor Biology.

[17]  Yan Zhang,et al.  Similar to Spironolactone, Oxymatrine Is Protective in Aldosterone-Induced Cardiomyocyte Injury via Inhibition of Calpain and Apoptosis-Inducing Factor Signaling , 2014, PloS one.

[18]  Y. Cao,et al.  Comparison of the Exposure of Glycyrrhizin and its Metabolites and the Pseudoaldosteronism after Intravenous Administration of Alpha- and Beta-glycyrrhizin in Rat , 2013, Drug Research.

[19]  Yingguang Sun,et al.  A comparative study on the pharmacokinetics of a traditional Chinese herbal preparation with the single herb extracts in rats by LC-MS/MS method. , 2013, Journal of pharmaceutical and biomedical analysis.

[20]  Xiao Yan Huang,et al.  Effect of oxymatrine, the active component from Radix Sophorae flavescentis (Kushen), on ventricular remodeling in spontaneously hypertensive rats. , 2013, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[21]  Xiao-Yi Zeng,et al.  Screening for the efficacy on lipid accumulation in 3T3-L1 cells is an effective tool for the identification of new anti-diabetic compounds. , 2012, Biochemical pharmacology.

[22]  Hui Zhao,et al.  Diammonium Glycyrrhizinate Upregulates PGC-1α and Protects against Aβ1–42-Induced Neurotoxicity , 2012, PloS one.

[23]  P. He,et al.  Antifibrotic effects of glycyrrhizin and matrine in vitro and in vivo , 2012 .

[24]  Jinyan Xie,et al.  Effects of oxymatrine on sympathoexcitatory reflex induced by myocardial ischemic signaling mediated by P2X3 receptors in rat SCG and DRG , 2011, Brain Research Bulletin.

[25]  Xiong Cai,et al.  Effect of oxymatrine on the replication cycle of hepatitis B virus in vitro. , 2010, World journal of gastroenterology.

[26]  X. Ren,et al.  Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus , 2009, Antiviral Research.

[27]  P. He,et al.  Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine. , 2009, Chemico-biological interactions.

[28]  Z. Lou,et al.  Determination of oxymatrine and its metabolite matrine in rat blood and dermal microdialysates by high throughput liquid chromatography/tandem mass spectrometry. , 2009, Journal of pharmaceutical and biomedical analysis.

[29]  Zhi-xiang Shen,et al.  Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia , 2008, Proceedings of the National Academy of Sciences.

[30]  A. Ma,et al.  Sensitive quantitative determination of oxymatrine and matrine in rat plasma by capillary electrophoresis with stacking induced by moving reaction boundary. , 2007, Analytica chimica acta.

[31]  B. Potter,et al.  Inhibition of human and rat 11β-hydroxysteroid dehydrogenase type 1 by 18β-glycyrrhetinic acid derivatives , 2007, The Journal of Steroid Biochemistry and Molecular Biology.

[32]  Xueying Sun,et al.  Anti-apoptosis Effects of Oxymatrine Protect the Liver from Warm Ischemia Reperfusion Injury in Rats , 2005, World Journal of Surgery.

[33]  Jun Ye,et al.  Capsule oxymatrine in treatment of hepatic fibrosis due to chronic viral hepatitis: a randomized, double blind, placebo-controlled, multicenter clinical study. , 2004, World journal of gastroenterology.

[34]  Toshitsugu Sato,et al.  Glycyrrhizin and related compounds down-regulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line , 2004, International Immunopharmacology.

[35]  T. Suda,et al.  A case of pseudoaldosteronism, accompanied with hypocalcemia and exaggerated ACTH response. , 2004, Endocrine journal.

[36]  H. Sakagami,et al.  Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra. , 2003, Fitoterapia.

[37]  M. Saeedi,et al.  Comparison of antioxidant activity of extract from roots of licorice (Glycyrrhiza glabra L.) to commercial antioxidants in 2% hydroquinone cream. , 2003, Journal of cosmetic science.

[38]  Xiwen He,et al.  Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction , 2003, Analytical and bioanalytical chemistry.

[39]  W. Hop,et al.  ‘Pseudo‐aldosteronism’ induced by intravenous glycyrrhizin treatment of chronic hepatitis C patients , 2001, Journal of gastroenterology and hepatology.

[40]  D. Nixon,et al.  Licorice and Cancer , 2001, Nutrition and cancer.

[41]  K. Kobashi,et al.  Bioavailability Study of Glycyrrhetic Acid after Oral Administration of Glycyrrhizin in Rats; Relevance to the Intestinal Bacterial Hydrolysis , 1996, The Journal of pharmacy and pharmacology.

[42]  T. Saruta,et al.  Renin-dependency of glycyrrhizin-induced pseudoaldosteronism. , 1991, Endocrinologia japonica.

[43]  D. Mebs.  Progress in the characterization of venoms and standardization of antivenoms: 44 pp. Geneva: WHO Offset Publication No. 58 (1981) , 1981 .

[44]  F. E. Revers.  Clinical and pharmacological investigations on extract of licorice. , 2009, Acta medica Scandinavica. Supplementum.