Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site.
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P. Fossa | G. Leoncini | L. Mosti | D. Piras | G. Grossi | G. Roma | M. G. Signorello | M. Di Braccio | D. Bruzzese | M. Signorello