Staged Endovascular and Surgical Management of a Mycotic Pseudoaneurysm After Pancreas Transplant.

Mycotic pseudoaneurysms are a rare, life-threatening complication after pancreas transplant. There have been limited reports of endovascular treatment of mycotic pseudoaneurysms in pancreas transplant recipients. Herein, we report on a case of a mycotic pseudoaneurysm from Pseudomonas aeruginosa after pancreas transplant. A 53-year-old male recipient underwent an uneventful simultaneous pancreas and kidney transplant. He was readmitted 48 days posttransplant with fevers and rigors. Pan-cultures were performed and broad-spectrum antibiotics were initiated. Imaging studies demonstrated a large mycotic pseudoaneurysm arising from the right common iliac artery adjacent to the arterial Y-graft anastomosis of the transplant pancreas. Endovascular stent placement was used to exclude the pseudoaneurysm prior to transplant pancreatectomy. During pancreatectomy, the lateral wall of the common iliac artery was found to be necrotic with significant exposure of the endovascular stent. After ligation and excision of the common iliac artery, a femorofemoral bypass was performed to revascularize the lower extremity. This case report highlights the advantage of a staged endovascular and surgical management strategy for complex mycotic pseudoaneurysms after pancreas transplant.

[1]  A. Webster,et al.  Endovascular Management of Mycotic Pseudoaneurysm After Pancreas Transplantation: Case Report and Literature Review. , 2020, Transplantation Proceedings.

[2]  R. Kandaswamy,et al.  Significant arterial complications after pancreas transplantation—A single‐center experience and review of literature , 2017, Clinical transplantation.

[3]  J. Nicastro,et al.  Arterio-Enteric Fistula in Failed Enteric-Drained Pancreas Transplants: An Impending Danger , 2013, International Journal of Angiology.

[4]  K. Brayman,et al.  Endovascular Management of Vascular Complications in Pancreatic Transplants , 2012, Vascular and Endovascular Surgery.

[5]  Matthew S. Johnson,et al.  Vascular catastrophes following pancreas transplantation: an evolution in strategy at a single center , 2012, Clinical transplantation.

[6]  G. Jaffers,et al.  Endovascular Repair of a Pancreatic Allograft Mycotic Aneurysm: Two-year Follow-up , 2011, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

[7]  W. Cwikiel,et al.  Endovascular Management of Acute Enteric Bleeding from Pancreas Transplant , 2007, CardioVascular and Interventional Radiology.

[8]  K. Mekeel,et al.  Successful endovascular treatment of a leaking pseudoaneurysm without graft loss after simultaneous pancreas and kidney transplantation. , 2006, Transplantation.

[9]  L. Benozzi,et al.  Embolization of a ruptured pseudoaneurysm with massive hemorrhage following pancreas transplantation: a case report. , 2005, Transplantation proceedings.

[10]  P. Higgins,et al.  Massive lower gastrointestinal bleeding after rejection of pancreatic transplants , 2005, Nature Clinical Practice Gastroenterology &Hepatology.

[11]  H. Jeon,et al.  Atypical Etiology of Massive Gastrointestinal Bleeding: Arterio-Enteric Fistula following Enteric Drained Pancreas Transplant , 2004, The American surgeon.

[12]  J. Tuttle-Newhall,et al.  Massive gastrointestinal hemorrhage due to rupture of a donor pancreatic artery pseudoaneurysm in a pancreas transplant patient , 2004, Clinical transplantation.

[13]  L. Stein,et al.  Pseudoaneurysm of the superior mesenteric artery after pancreas transplantation treated by endovascular stenting. , 2001, Transplantation.