论文信息 - The Isolation of Two New Fungal Inhibitors of 35S-TBPS Binding to the Brain GABAA/benzodiazepine chloride Channel Receptor Complex

The Isolation of Two New Fungal Inhibitors of 35S-TBPS Binding to the Brain GABAA/benzodiazepine chloride Channel Receptor Complex

Abstract Bioassay-guided fractionation of the ethyl acetate extracts of the culture filtrate of the fungal culture HA 137–89 yielded the two salicylic acid derivatives 1 and 2, as inhibitors of the binding of 35S-TBPS to the GABAA/benzodiazepine chloride channel receptor complex in vitro. Their structures were determined by spectroscopic and chemical methods.

H. Anke | O. Sterner | M. Nielsen | M. Witt | R. Shan

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