Clinical studies of gas exchange during ventilatory support--a method using the Siemens-Elema CO2 analyzer.

We describe a new portable infra-red analyses for use with the Siemens-Elema Servo ventilator. The sensor head constitutes a Y-piece connecting the patient to the ventilator tubing, and gives instant carbon dioxide determination. It is based upon simple principles that can be realized with modern techniques, offering for instance freedom from interference by anaesthetic gases, and eliminating the need for calibration. A non-zero inspired carbon dioxide concentration interferes with the measurements. Integration of the carbon dioxide signal with the flow signal from the Servo ventilator yields data about carbon dioxide excretion, and additional calculation yields VD/VT if PaCO2 is known. The accuracy of determination of end-tidal carbon dioxide and carbon dioxide elimination was found to be adequate for research purposes, and that of VD/VT for clinical purposes. The device is considered to be of value in the operating theatre and intensive care unit, for monitoring, as a guide to ventilatory needs, and for the investigation of the magnitude and causes of increased deadspace.

[1]  P. F. Scholander Analyzer for accurate estimation of respiratory gases in one-half cubic centimeter samples. , 1947, The Journal of biological chemistry.

[2]  B Jonson,et al.  Monitoring of ventilation and lung mechanics during automatic ventilation. A new device. , 1975, Bulletin de physio-pathologie respiratoire.

[3]  C. Bohr Ueber die Lungenathmung1 , 1891 .

[4]  B. Jonson,et al.  Cardiorespiratory and metabolic effects of profound hypothermia , 1978, Critical care medicine.

[5]  O. Norlander,et al.  VENTILATION NOMOGRAM FOR THE NEWBORN AND SMALL CHILDREN TO BE USED WITH THE ENGSTROM RESPIRATOR , 1962 .

[6]  C. Engstrom HERZOG P: Ventilation nomogram for practical use with the Engstrom respirator. , 1959, Acta chirurgica Scandinavica. Supplementum.

[7]  D V BATES,et al.  The respiratory dead space measured by single breath analysis of oxygen, carbon dioxide, nitrogen or helium. , 1954, The Journal of clinical investigation.

[8]  B Jonson,et al.  A Servo‐Controlled Ventilator Measuring Expired Minute Volume, Airway Flow and Pressure , 1972, Acta anaesthesiologica Scandinavica. Supplementum.

[9]  E. Radford,et al.  Ventilation standards for use in artificial respiration. , 1955, Journal of applied physiology.

[10]  B. Jonson,et al.  Criteria for Early Extubation After Intracardiac Surgery in Adults , 1977, Anesthesia and analgesia.

[11]  VENTILATION NOMOGRAM FOR THE NEWBORN AND SMALL CHILDREN TO BE USED WITH THE ENGSTROM RESPIRATOR , 1962 .

[12]  Engstrom Cg HERZOG P: Ventilation nomogram for practical use with the Engstrom respirator. , 1959 .

[13]  L. Okmian ARTIFICIAL VENTILATION BY RESPIRATOR FOR NEWBORN INFANTS DURING ANAESTHESIA A Method Using a New Formula and a New Nomogram , 1963, Acta anaesthesiologica Scandinavica.