Surface Enrichment and Depletion of the Active Ingredient in Spray Dried Amorphous Solid Dispersions

[1]  M. Woo,et al.  The influence of the chemical surface composition on the drying process of milk droplets , 2016 .

[2]  S. Palzer,et al.  Predicting the surface composition of a spray-dried particle by modelling component reorganization in a drying droplet , 2016 .

[3]  M. Woo,et al.  The impact of atomization on the surface composition of spray-dried milk droplets. , 2016, Colloids and surfaces. B, Biointerfaces.

[4]  D. Contini,et al.  XPS surface chemical characterization of atmospheric particles of different sizes , 2015 .

[5]  S. Palzer,et al.  Influence of Feed Composition and Drying Parameters on the Surface Composition of a Spray-Dried Multicomponent Particle , 2015 .

[6]  J. Petit,et al.  Impact of Spray-Drying Process Parameters on Dairy Powder Surface Composition and Properties , 2015 .

[7]  Daryl R. Williams Particle Engineering in Pharmaceutical Solids Processing: Surface Energy 
Considerations , 2015, Current pharmaceutical design.

[8]  B. Bergenståhl,et al.  Surface Composition and Morphology of Particles Dried Individually and by Spray Drying , 2015 .

[9]  Amrit Paudel,et al.  Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations. , 2013, International journal of pharmaceutics.

[10]  J. Rantanen,et al.  Critical Solvent Properties Affecting the Particle Formation Process and Characteristics of Celecoxib-Loaded PLGA Microparticles via Spray-Drying , 2012, Pharmaceutical Research.

[11]  H. Sidhu,et al.  Theoretical probing of the phenomenon of the formation of the outermost surface layer of a multi-component particle, and the surface chemical composition after the rapid removal of water in spray drying , 2011 .

[12]  B. Cuq,et al.  X-ray photoelectron spectroscopy for wheat powders: measurement of surface chemical composition. , 2011, Journal of agricultural and food chemistry.

[13]  Lian Yu,et al.  Solubilities of crystalline drugs in polymers: an improved analytical method and comparison of solubilities of indomethacin and nifedipine in PVP, PVP/VA, and PVAc. , 2010, Journal of pharmaceutical sciences.

[14]  Timo Laaksonen,et al.  Electrospraying, spray drying and related techniques for production and formulation of drug nanoparticles , 2010, Expert opinion on drug delivery.

[15]  K. Cal,et al.  Spray drying technique: II. Current applications in pharmaceutical technology. , 2010, Journal of pharmaceutical sciences.

[16]  Xiao Dong Chen,et al.  Surface composition of industrial spray-dried milk powders. 3. Changes in the surface composition during long-term storage. , 2009 .

[17]  E. Kim,et al.  Surface composition of industrial spray-dried milk powders. 1. Development of surface composition during manufacture. , 2009 .

[18]  M. Descamps,et al.  Solid State Amorphization of Pharmaceuticals , 2009 .

[19]  T. Langrish,et al.  A Distributed Parameter Model for Particles in the Spray Drying Process , 2009 .

[20]  Lian Yu,et al.  Solubility of Small-Molecule Crystals in Polymers: d-Mannitol in PVP, Indomethacin in PVP/VA, and Nifedipine in PVP/VA , 2009, Pharmaceutical Research.

[21]  D. T. Friesen,et al.  Hydroxypropyl methylcellulose acetate succinate-based spray-dried dispersions: an overview. , 2008, Molecular pharmaceutics.

[22]  Reinhard Vehring,et al.  Pharmaceutical Particle Engineering via Spray Drying , 2007, Pharmaceutical Research.

[23]  Reinhard Vehring,et al.  Particle formation in spray drying , 2007 .

[24]  M. Ré Formulating Drug Delivery Systems by Spray Drying , 2006 .

[25]  J. Scher,et al.  Surface composition of dairy powders observed by X-ray photoelectron spectroscopy and effects on their rehydration properties. , 2006, Colloids and surfaces. B, Biointerfaces.

[26]  Arun S. Mujumdar,et al.  Spray Dryers: Modeling and Simulation , 2006 .

[27]  E. Kim,et al.  Effect of surface composition on the flowability of industrial spray-dried dairy powders. , 2005, Colloids and surfaces. B, Biointerfaces.

[28]  A. Paradkar,et al.  Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique. , 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[29]  Geoffrey Lee,et al.  Surface Composition of Spray-Dried Particles of Bovine Serum Albumin/Trehalose/Surfactant , 2000, Pharmaceutical Research.

[30]  George Zografi,et al.  Physical Properties of Solid Molecular Dispersions of Indomethacin with Poly(vinylpyrrolidone) and Poly(vinylpyrrolidone-co-vinyl-acetate) in Relation to Indomethacin Crystallization , 1999, Pharmaceutical Research.

[31]  X. Dong Chen,et al.  On the Mechanisms of Surface Formation and the Surface Compositions of Industrial Milk Powders , 2003 .

[32]  P. M. Kelly,et al.  Influence of processing variables on the physicochemical properties of spray dried fat-based milk powders , 2002 .

[33]  L Yu,et al.  Amorphous pharmaceutical solids: preparation, characterization and stabilization. , 2001, Advanced drug delivery reviews.

[34]  J. Koberstein,et al.  Molecular weight dependence and end-group effects on the surface tension of poly(dimethylsiloxane) , 1993 .

[35]  Lapp,et al.  Direct measurements of polymer depletion layers by neutron reflectivity. , 1991, Physical review letters.

[36]  C. King,et al.  Changes in particle morphology during drying of drops of carbohydrate solutions and food liquids. 2. Effects of drying rate , 1990 .

[37]  M. Davies,et al.  An analysis of the surface chemical structure of polymethacrylate (Eudragit) film coating polymers by XPS , 1989 .

[38]  D. Ausserré,et al.  Concentration dependence of the interfacial depletion layer thickness for polymer solutions in contact with nonadsorbing walls , 1986 .

[39]  C. J. King,et al.  FACTORS GOVERNING SURFACE MORPHOLOGY OF SPRAY-DRIED AMORPHOUS SUBSTANCES , 1985 .

[40]  C. Taupin,et al.  Study of the surface tension of polymer solutions: theory and experiments. Good solvent conditions , 1983 .

[41]  P. G. de Gennes,et al.  Polymer solutions near an interface. Adsorption and depletion layers , 1981 .

[42]  M. Naudts,et al.  Influence of process variables on some whole milk powder characteristics. , 1976 .

[43]  G. Gaines,et al.  The molecular weight dependence of polymer surface tension , 1969 .

[44]  W. Gauvin,et al.  Evaporation rates in spray drying , 1960 .

[45]  W. R. Marshall,et al.  Evaporation from drops containing dissolved solids , 1960 .