Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.
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Robert V Farese | S. Young | M. Linton | D. Sanan | D A Sanan | D L Newland | R V Farese | D. Johnson | D A Purcell-Huynh | D F Johnson | L M Flynn | V Pierotti | M F Linton | S G Young | V. Pierotti | D. Newland | D. Purcell-Huynh | L. Flynn
[1] R. Hammer,et al. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. , 1993, The Journal of clinical investigation.
[2] A. Lusis,et al. Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis. , 1990, Journal of lipid research.
[3] R. Hammer,et al. Atherogenesis in transgenic mice expressing human apolipoprotein(a) , 1992, Nature.
[4] R. Krauss,et al. Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI , 1991, Nature.
[5] J. Parks,et al. Childhood consumption of dietary polyunsaturated fat lowers risk for coronary artery atherosclerosis in African green monkeys. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.
[6] A. Lusis,et al. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[7] B. Taylor,et al. Genetic factors controlling structure and expression of apolipoproteins B and E in mice. , 1987, The Journal of biological chemistry.
[8] A. Lusis,et al. Genetic control of inflammatory gene induction and NF-kappa B-like transcription factor activation in response to an atherogenic diet in mice. , 1993, The Journal of clinical investigation.
[9] B. Paigen,et al. Atherosclerosis susceptibility differences among progenitors of recombinant inbred strains of mice. , 1990, Arteriosclerosis.
[10] E. Rubin,et al. Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. , 1994, The Journal of clinical investigation.
[11] B. Paigen,et al. Synthetic low and high fat diets for the study of atherosclerosis in the mouse. , 1990, Journal of lipid research.
[12] T. Innerarity,et al. Apolipoprotein B mRNA editing. Direct determination of the edited base and occurrence in non-apolipoprotein B-producing cell lines. , 1990, The Journal of biological chemistry.
[13] J. Colca,et al. Lipoprotein profile characterization of the KKA(y) mouse, a rodent model of type II diabetes, before and after treatment with the insulin-sensitizing agent pioglitazone. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.
[14] J. Parks,et al. Hepatic ACAT activity in African green monkeys is highly correlated to plasma LDL cholesteryl ester enrichment and coronary artery atherosclerosis. , 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.
[15] B. Paigen,et al. Atherosclerosis in the mouse , 1989 .
[16] B. Paigen,et al. Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H. , 1991, Journal of lipid research.
[17] Y. Marcel,et al. Use of bacterial expression cloning to localize the epitopes for a series of monoclonal antibodies against apolipoprotein B100. , 1990, The Journal of biological chemistry.
[18] D K Burns,et al. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. , 1994, The Journal of clinical investigation.
[19] Robert V Farese,et al. Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). , 1993, The Journal of clinical investigation.
[20] N. Maeda,et al. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. , 1992, Science.
[21] S. Young,et al. Parallel expression of the MB19 genetic polymorphism in apoprotein B-100 and apoprotein B-48. Evidence that both apoproteins are products of the same gene. , 1986, The Journal of biological chemistry.
[22] S. Young. Recent Progress in Understanding Apolipoprotein B , 1990, Circulation.
[23] N. Davidson. RNA editing of the apolipoprotein B gene A mechanism to regulate the atherogenic potential of intestinal lipoproteins? , 1994, Trends in cardiovascular medicine.
[24] N. Maeda,et al. Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[25] R. Ross,et al. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[26] R. Leboeuf,et al. Regulation by nutritional status of lipids and apolipoproteins A-I, A-II, and A-IV in inbred mice. , 1994, Journal of lipid research.
[27] R. Mahley,et al. Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA. , 1993, The Journal of biological chemistry.
[28] K. Marotti,et al. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein , 1993, Nature.
[29] E. Rubin,et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells , 1992, Cell.
[30] R. Mahley,et al. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.
[31] N. Maeda,et al. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[32] R. Krauss,et al. Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia. , 1990, Journal of lipid research.
[33] S. Grundy,et al. Comparison of effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. , 1985, Journal of lipid research.
[34] M. Brown,et al. A receptor-mediated pathway for cholesterol homeostasis. , 1986, Science.
[35] J. Scott,et al. Regional specificities of monoclonal anti-human apolipoprotein B antibodies. , 1988, Journal of lipid research.
[36] R. Williams,et al. Quantitative assessment of atherosclerotic lesions in mice. , 1987, Atherosclerosis.
[37] S. Grundy,et al. Influence of polyunsaturated fats on composition of plasma lipoproteins and apolipoproteins. , 1982, Journal of lipid research.