Restoration of plakoglobin expression in bladder carcinoma cell lines suppresses cell migration and tumorigenic potential

[1]  D. Canes,et al.  Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo , 2005, International journal of cancer.

[2]  V. Kosma,et al.  The expression and prognostic value of alpha-, beta- and gamma-catenins in renal cell carcinoma. , 2004, Anticancer research.

[3]  P. Hu,et al.  Keratinocyte adherens junctions initiate nuclear signaling by translocation of plakoglobin from the membrane to the nucleus. , 2003, The Journal of investigative dermatology.

[4]  W. Schulz,et al.  E-cadherin involved in inactivation of WNT/β-catenin signalling in urothelial carcinoma and normal urothelial cells , 2003, British Journal of Cancer.

[5]  Y. Miller,et al.  γ-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth , 2002, Oncogene.

[6]  E. Fearon,et al.  Cadherin and catenin alterations in human cancer , 2002, Genes, chromosomes & cancer.

[7]  D. Nass,et al.  Reduced expression of plakoglobin correlates with adverse outcome in patients with neuroblastoma. , 2001, The American journal of pathology.

[8]  Kathleen R. Cho,et al.  γ-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of β-catenin , 2000, Genes & Development.

[9]  K. Endo,et al.  Immunoreactive E-cadherin, alpha-catenin, beta-catenin, and gamma-catenin proteins in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, and patients' survival. , 2000, Human pathology.

[10]  J. Schalken,et al.  Complex cadherin expression in human prostate cancer cells , 2000, International journal of cancer.

[11]  A. Børresen-Dale,et al.  Re‐expression of E‐cadherin, α‐catenin and β‐catenin, but not of γ‐catenin, in metastatic tissue from breast cancer patients , 2000 .

[12]  N. Konishi,et al.  E-cadherin and α-, β- and γ-catenin expression in prostate cancers: correlation with tumour invasion , 1999, British Journal of Cancer.

[13]  H. Schwarz,et al.  Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice. , 1999, Development.

[14]  K. Syrigos,et al.  Altered gamma-catenin expression correlates with poor survival in patients with bladder cancer. , 1998, The Journal of urology.

[15]  B. Geiger,et al.  Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer. , 1998, Current opinion in cell biology.

[16]  A. Sparks,et al.  Identification of c-MYC as a target of the APC pathway. , 1998, Science.

[17]  D. Garrod,et al.  Desmosomal adhesion inhibits invasive behavior. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. Izbicki,et al.  Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[19]  C. Marcozzi,et al.  Coexpression of both types of desmosomal cadherin and plakoglobin confers strong intercellular adhesion. , 1998, Journal of cell science.

[20]  Mark Peifer,et al.  β-Catenin as Oncogene--The Smoking Gun , 1997, Science.

[21]  J. Schalken,et al.  Prognostic value of cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120cas) in bladder tumors. , 1996, Cancer research.

[22]  B. Geiger,et al.  Suppression of tumorigenicity by plakoglobin: an augmenting effect of N- cadherin , 1996, The Journal of cell biology.

[23]  H. Lynch,et al.  The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[24]  E. Gelmann,et al.  Alterations in β-Catenin Phosphorylation and Plakoglobin Expression in Human Breast Cancer Cells , 1994 .

[25]  S. Povey,et al.  Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines. , 1986, Cancer research.

[26]  A. Berdal,et al.  Altered plakoglobin expression at mRNA and protein levels correlates with clinical outcome in patients with oropharynx squamous carcinomas. , 2004, Human pathology.

[27]  T. Wheeler,et al.  E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder. , 2001, Urology.

[28]  E. Fearon,et al.  gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. , 2000, Genes & development.

[29]  M. Pasdar,et al.  Plakoglobin induces desmosome formation and epidermoid phenotype in N-cadherin-expressing squamous carcinoma cells deficient in plakoglobin and E-cadherin. , 1998, Cell motility and the cytoskeleton.

[30]  M. Peifer Beta-catenin as oncogene: the smoking gun. , 1997, Science.

[31]  J. Bosson,et al.  Expression of E-cadherin and alpha-,beta- and gamma-catenins in human bladder carcinomas: are they good prognostic factors? , 1997, Invasion & metastasis.

[32]  R. Weinstein,et al.  Correlation between numbers of desmosomes and the aggressiveness of transitional cell carcinoma in human urinary bladder , 1981, Cancer.