TNF-α suppresses sweat gland differentiation of MSCs by reducing FTO-mediated m6A-demethylation of Nanog mRNA

[1]  Xiaobing Fu.  Regenerative medicine in China: new advances and hopes , 2018, Science China Life Sciences.

[2]  R. Hajjar,et al.  FTO-Dependent N6-Methyladenosine Regulates Cardiac Function During Remodeling and Repair , 2018, Circulation.

[3]  James E. Bradner,et al.  R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling , 2018, Cell.

[4]  Jaewon Park,et al.  Dynamic m6A modification regulates local translation of mRNA in axons , 2017, Nucleic acids research.

[5]  F. Liu,et al.  m6A modulates haematopoietic stem and progenitor cell specification , 2017, Nature.

[6]  Shuo Chen,et al.  Tumor necrosis factor α accelerates Hep-2 cells proliferation by suppressing TRPP2 expression , 2017, Science China Life Sciences.

[7]  Zhike Lu,et al.  m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells , 2017, Cell reports.

[8]  Jie Jin,et al.  FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. , 2017, Cancer cell.

[9]  Chuanzhao Zhang,et al.  Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA , 2016, Proceedings of the National Academy of Sciences.

[10]  B. Yao,et al.  3D bioprinted extracellular matrix mimics facilitate directed differentiation of epithelial progenitors for sweat gland regeneration. , 2016, Acta biomaterialia.

[11]  Xi Chen,et al.  Three-dimensional bioprinting of embryonic stem cells directs highly uniform embryoid body formation , 2015, Biofabrication.

[12]  D. Schlessinger,et al.  Eccrine sweat gland development and sweat secretion , 2015, Experimental dermatology.

[13]  Xiaobing Fu,et al.  Three-dimensional co-culture of BM-MSCs and eccrine sweat gland cells in Matrigel promotes transdifferentiation of BM-MSCs , 2015, Journal of Molecular Histology.

[14]  Chuan He,et al.  N 6 -methyladenosine Modulates Messenger RNA Translation Efficiency , 2015, Cell.

[15]  S. Tavazoie,et al.  N6-methyladenosine marks primary microRNAs for processing , 2015, Nature.

[16]  X. Zhang,et al.  Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice. , 2015, Experimental cell research.

[17]  Erez Y. Levanon,et al.  m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation , 2015, Science.

[18]  Yi Xing,et al.  m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. , 2014, Cell stem cell.

[19]  Cheng Luo,et al.  Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5 , 2014, Nucleic acids research.

[20]  G. Shaw,et al.  TNFα and IL-1β influence the differentiation and migration of murine MSCs independently of the NF-κB pathway , 2014, Stem Cell Research & Therapy.

[21]  Samie R. Jaffrey,et al.  The dynamic epitranscriptome: N6-methyladenosine and gene expression control , 2014, Nature Reviews Molecular Cell Biology.

[22]  Gideon Rechavi,et al.  Gene expression regulation mediated through reversible m6A RNA methylation , 2014, Nature Reviews Genetics.

[23]  J. Karp,et al.  Mesenchymal stem cells: immune evasive, not immune privileged , 2014, Nature Biotechnology.

[24]  C. Yun,et al.  A novel protein, Pho92, has a conserved YTH domain and regulates phosphate metabolism by decreasing the mRNA stability of PHO4 in Saccharomyces cerevisiae. , 2014, The Biochemical journal.

[25]  Samir Adhikari,et al.  Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase , 2014, Cell Research.

[26]  Miao Yu,et al.  A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation , 2013, Nature chemical biology.

[27]  Arne Klungland,et al.  ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. , 2013, Molecular cell.

[28]  S. Hung,et al.  Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells. , 2012, Molecular cell.

[29]  H. Pasolli,et al.  Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair , 2012, Cell.

[30]  M. Kupiec,et al.  Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq , 2012, Nature.

[31]  Chengqi Yi,et al.  N6-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO , 2011, Nature chemical biology.

[32]  L. Evers,et al.  The biology of burn injury , 2010, Experimental dermatology.

[33]  R. Tuan,et al.  Interleukin‐6 maintains bone marrow‐derived mesenchymal stem cell stemness by an ERK1/2‐dependent mechanism , 2009, Journal of cellular biochemistry.

[34]  Ranjna C Dutta,et al.  Cell-interactive 3D-scaffold; advances and applications. , 2009, Biotechnology advances.

[35]  Hiroyuki Miyoshi,et al.  The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair , 2009, Science.

[36]  J. Hamilton,et al.  Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation. , 2009, Osteoarthritis and cartilage.

[37]  Xiaobing Fu,et al.  Regeneration of functional sweat gland‐like structures by transplanted differentiated bone marrow mesenchymal stem cells , 2009, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[38]  W. Liu,et al.  BMC Cell Biology BioMed Central , 2007 .

[39]  A. Caplan.  Adult mesenchymal stem cells for tissue engineering versus regenerative medicine , 2007, Journal of cellular physiology.

[40]  T. Krieg,et al.  Inflammation in wound repair: molecular and cellular mechanisms. , 2007, The Journal of investigative dermatology.

[41]  D. Church,et al.  Burn Wound Infections , 2006, Clinical Microbiology Reviews.

[42]  Hidezo Mori,et al.  Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction , 2006, Nature Medicine.

[43]  D. Kaplan,et al.  Porosity of 3D biomaterial scaffolds and osteogenesis. , 2005, Biomaterials.

[44]  R. Tuan,et al.  Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy , 2004, Journal of cellular and molecular medicine.

[45]  William P Cheshire,et al.  Disorders of sweating. , 2003, Seminars in neurology.

[46]  R. Weinstein,et al.  The epidemiology of burn wound infections: then and now. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[47]  W. Janssen,et al.  Adult Bone Marrow Stromal Cells Differentiate into Neural Cells in Vitro , 2000, Experimental Neurology.

[48]  Gene Kopen,et al.  Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: Variations in yield, growth, and differentiation , 1999, Journal of cellular biochemistry.

[49]  B. Moss,et al.  Methylated nucleotides block 5′ terminus of HeLa cell messenger RNA , 1975, Cell.

[50]  Miao Yu,et al.  A METTL 3-METTL 14 complex mediates mammalian nuclear RNA N 6-adenosine methylation , 2016 .

[51]  Yasuyuki Fujita,et al.  Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type , 2008 .

[52]  J. Hurwitz,et al.  Messenger RNA. , 1962, Scientific American.