[Isolation and identification of the ligustilide compounds from the root of Angelica sinensis].

OBJECTIVE To find out substance basis of pharmacological activities of Angelica sinensis. METHOD Chromatographic methods were used to isolate the chemical components, and spectroscopic methods were used to identify their structures. RESULT Five compounds were isolated from the ethanol extract of the roots of Angelica sinensis. Their structures were identified as: (Z)-ligustilide, (Z)-6,7-epoxyligustilide, (Z)-6,7-cis-dihydroxyligustilide, (E)-6,7-cis-dihydroxy-ligustilide and 11-angeloylsenkyunolide F. CONCLUSION 11-angeloylsenkyunolide F was obtained from Angelica sinensis for the first time.