Parental presence during induction enhances the effect of oral midazolam on emergence behavior of children undergoing general anesthesia

Background:  Pre‐anesthetic anxiety and emergence agitation are major challenges for anesthesiologists in pediatric anesthesia. Thus, sedative premedication and parental presence during induction of anesthesia (PPIA) are used to treat pre‐anesthetic anxiety in children. The aim of the present study was to test if a combination of mother presence and midazolam premedication is effective for improving emergence condition in children undergoing general anesthesia.

[1]  Y. Arai,et al.  Comparison of a combination of midazolam and diazepam and midazolam alone as oral premedication on preanesthetic and emergence condition in children , 2005, Acta anaesthesiologica Scandinavica.

[2]  S. Kaya,et al.  Oral ketamine premedication can prevent emergence agitation in children after desflurane anaesthesia * , 2004, Paediatric anaesthesia.

[3]  L. Eidelman,et al.  Premedication with midazolam in young children: a comparison of four routes of administration , 2002, Paediatric anaesthesia.

[4]  B. Trabold,et al.  A comparison of two different doses of ketamine with midazolam and midazolam alone as oral preanaesthetic medication on recovery after sevoflurane anaesthesia in children , 2002, Paediatric anaesthesia.

[5]  R. Hannallah,et al.  Propofol or midazolam do not reduce the incidence of emergence agitation associated with desflurane anaesthesia in children undergoing adenotonsillectomy , 2002, Paediatric anaesthesia.

[6]  G. Hirshberg,et al.  Emergence behaviour in children: defining the incidence of excitement and agitation following anaesthesia , 2002, Paediatric anaesthesia.

[7]  J. Cravero,et al.  Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery: a comparison with halothane , 2000, Paediatric anaesthesia.

[8]  L. Mayes,et al.  Parental Presence and a Sedative Premedicant for Children Undergoing Surgery: A Hierarchical Study , 2000, Anesthesiology.

[9]  K. Taeger,et al.  Oral preanaesthetic medication for children: double-blind randomized study of a combination of midazolam and ketamine vs midazolam or ketamine alone. , 2000, British journal of anaesthesia.

[10]  A. Chuang,et al.  Sublingual midazolam premedication in children: a dose response study , 1998, Paediatric anaesthesia.

[11]  H. Burgstaller,et al.  Oral premedication with midazolam in paediatric anaesthesia. Effects on sedation and gastric contents , 1997, Paediatric anaesthesia.

[12]  L. Mayes,et al.  Premedication in the United States: A Status Report , 1997, Anesthesia and analgesia.

[13]  Z. Kain,et al.  Parental presence during induction of anaesthesia: practice differences between the United States and Great Britain , 1996, Paediatric anaesthesia.

[14]  C. Johnston,et al.  Preoperative parental anxiety predicts behavioural and emotional responses to induction of anaesthesia in children , 1990, Canadian journal of anaesthesia = Journal canadien d'anesthesie.