Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary Hypertension
暂无分享,去创建一个
J. Sembrat | E. Cifuentes-Pagano | P. Pagano | E. DeVallance | D. D. de Jesus | I. Ghouleh | E. DeVallance | Christopher M. Dustin | Eugenia Cifuentes-Pagano
[1] E. Jacinto,et al. Targeting mTOR and Metabolism in Cancer: Lessons and Innovations , 2019, Cells.
[2] R. Bryner,et al. Exercise training prevents the perivascular adipose tissue-induced aortic dysfunction with metabolic syndrome , 2019, Redox biology.
[3] M. Humbert,et al. Neutralization of CXCL12 attenuates established pulmonary hypertension in rats. , 2019, Cardiovascular research.
[4] Daniel N. Meijles,et al. Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice. , 2019, American journal of physiology. Lung cellular and molecular physiology.
[5] C. Camacho,et al. NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow , 2019, Redox biology.
[6] M. Gladwin,et al. Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration , 2019, Redox biology.
[7] M. Boerries,et al. CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury , 2018, Nature Communications.
[8] P. Carmeliet,et al. Endothelial Cell Metabolism in Health and Disease. , 2017, Trends in cell biology.
[9] A. Jemal,et al. Cancer statistics, 2018 , 2018, CA: a cancer journal for clinicians.
[10] S. Chan,et al. Metabolic dysfunction in pulmonary hypertension: from basic science to clinical practice , 2017, European Respiratory Review.
[11] Daniel N. Meijles,et al. Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation. , 2017, Clinical science.
[12] F. Chen,et al. Reactive Oxygen and Nitrogen Species in the Development of Pulmonary Hypertension , 2017, Antioxidants.
[13] S. Provencher,et al. The cancer theory of pulmonary arterial hypertension , 2017, Pulmonary circulation.
[14] J. Wharton,et al. Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2&agr; , 2016, Circulation.
[15] Mary E. Ziegler,et al. mTORC2 mediates CXCL12-induced angiogenesis , 2016, Angiogenesis.
[16] D. Saul,et al. CXCL12 promotes glycolytic reprogramming in acute myeloid leukemia cells via the CXCR4/mTOR axis , 2016, Leukemia.
[17] Wei Zhang,et al. CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks , 2016, Oncogene.
[18] Y. Miyagi,et al. Diverse Mechanisms of Sp1-Dependent Transcriptional Regulation Potentially Involved in the Adaptive Response of Cancer Cells to Oxygen-Deficient Conditions , 2015, Cancers.
[19] R. Benza,et al. Five-Year outcomes of patients enrolled in the REVEAL Registry. , 2015, Chest.
[20] B. Kang,et al. Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension. , 2015, Free radical biology & medicine.
[21] S. Scala. Molecular Pathways: Targeting the CXCR4–CXCL12 Axis—Untapped Potential in the Tumor Microenvironment , 2015, Clinical Cancer Research.
[22] A. Morton,et al. Elevated Plasma CXCL12α Is Associated with a Poorer Prognosis in Pulmonary Arterial Hypertension , 2015, PloS one.
[23] M. Mihailović,et al. Identification of transcription factors involved in the transcriptional regulation of the CXCL12 gene in rat pancreatic insulinoma Rin-5F cell line. , 2015, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[24] Guojun Wu,et al. Elevated expression of glutaminase confers glucose utilization via glutaminolysis in prostate cancer. , 2015, Biochemical and biophysical research communications.
[25] T. Bancroft,et al. The economic burden of pulmonary arterial hypertension (PAH) in the US on payers and patients , 2014, BMC Health Services Research.
[26] J. Blenis,et al. The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the eIF4B-Dependent Control of c-Myc Translation , 2014, Current Biology.
[27] T. Finkel,et al. Cellular mechanisms and physiological consequences of redox-dependent signalling , 2014, Nature Reviews Molecular Cell Biology.
[28] E. Michelakis,et al. The metabolic basis of pulmonary arterial hypertension. , 2014, Cell metabolism.
[29] M. Gladwin,et al. Selective Recapitulation of Conserved and Nonconserved Regions of Putative NOXA1 Protein Activation Domain Confers Isoform-specific Inhibition of Nox1 Oxidase and Attenuation of Endothelial Cell Migration* , 2013, The Journal of Biological Chemistry.
[30] Yuichiro J Suzuki,et al. Reactive oxygen species and antioxidants in pulmonary hypertension. , 2013, Antioxidants & redox signaling.
[31] Gregory Stephanopoulos,et al. The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4 , 2013, Cell.
[32] J. Joseph,et al. Real-time monitoring of reactive oxygen and nitrogen species in a multiwell plate using the diagnostic marker products of specific probes. , 2013, Methods in enzymology.
[33] J. Joseph,et al. Boronate probes as diagnostic tools for real time monitoring of peroxynitrite and hydroperoxides. , 2012, Chemical research in toxicology.
[34] R. Benza,et al. An evaluation of long-term survival from time of diagnosis in pulmonary arterial hypertension from the REVEAL Registry. , 2012, Chest.
[35] Jian Ding,et al. Inhibition of Chemokine (CXC Motif) Ligand 12/Chemokine (CXC Motif) Receptor 4 Axis (CXCL12/CXCR4)-mediated Cell Migration by Targeting Mammalian Target of Rapamycin (mTOR) Pathway in Human Gastric Carcinoma Cells* , 2012, The Journal of Biological Chemistry.
[36] J. Belperio,et al. A role for the CXCL12 receptor, CXCR7, in the pathogenesis of human pulmonary vascular disease , 2011, European Respiratory Journal.
[37] H. Coller,et al. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. , 2010, Genes & development.
[38] N. Voelkel,et al. Reversible or irreversible remodeling in pulmonary arterial hypertension. , 2010, American journal of respiratory cell and molecular biology.
[39] C. Dang,et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. , 2010, Cancer cell.
[40] F. Lanner,et al. Sp1 mediate hypoxia induced ephrinB2 expression via a hypoxia-inducible factor independent mechanism. , 2010, Biochemical and Biophysical Research Communications - BBRC.
[41] N. Voelkel,et al. Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation , 2009, Respiratory research.
[42] Gerard Manning,et al. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. , 2009, Cancer research.
[43] K. Krause,et al. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. , 2007, Physiological reviews.
[44] M. D'Addario,et al. Role of p38 in stress activation of Sp1. , 2006, Gene.
[45] F. Arenzana‐Seisdedos,et al. Functional characterization of SDF-1 proximal promoter. , 2005, Journal of molecular biology.
[46] R. Budhiraja,et al. Endothelial Dysfunction in Pulmonary Hypertension , 2004, Circulation.
[47] J. Loscalzo,et al. Glucose-6-phosphate Dehydrogenase Modulates Vascular Endothelial Growth Factor-mediated Angiogenesis* , 2003, Journal of Biological Chemistry.
[48] R. Neve,et al. Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons , 2003, The Journal of Neuroscience.
[49] M. D'Addario,et al. Interaction of p38 and Sp1 in a Mechanical Force-induced, β1 Integrin-mediated Transcriptional Circuit That Regulates the Actin-binding Protein Filamin-A* , 2002, The Journal of Biological Chemistry.
[50] J. Pouysségur,et al. Identification of Two Sp1 Phosphorylation Sites for p42/p44 Mitogen-activated Protein Kinases , 2002, The Journal of Biological Chemistry.
[51] Christine C. Hudson,et al. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. , 2000, Cancer research.