Hepatic arterial infusion of chemotherapy: the role of diagnostic and interventional radiology.

Hepatic arterial infusion of chemotherapy (HAIC) delivers higher local drug concentration to unresectable liver tumors with fewer significant systemic side-effects. It has been shown to produce better response rates than systemic chemotherapy and remains an important treatment option in patients with advanced, inoperable primary or metastatic hepatic tumors. Traditionally, catheters for HAIC were inserted surgically under general anesthesia. The advancement and expansion of interventional radiology have made it possible for catheter-port systems to be inserted percutaneously under local anesthesia with no significant increase in morbidity. A comprehensive review of the literature, techniques and complications of percutaneous placement of catheter-port systems for HAIC is presented in this article.

[1]  B. Dörken,et al.  Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: A phase II-study and historical comparison with the surgical approach , 2007, BMC Cancer.

[2]  H. Honda,et al.  Percutaneous femoral catheter placement for long-term chemotherapy infusions: preliminary technical results. , 2005, AJR. American journal of roentgenology.

[3]  K. Shirabe,et al.  New method of catheter-port system implantation in hepatic arterial infusion chemotherapy. , 2003, American journal of surgery.

[4]  T. Nishimura,et al.  Embolization of the right gastric artery before hepatic arterial infusion chemotherapy to prevent gastric mucosal lesions: approach through the hepatic artery versus the left gastric artery. , 2002, AJR. American journal of roentgenology.

[5]  T. Nishimura,et al.  Using n-butyl cyanoacrylate and the fixed-catheter-tip technique in percutaneous implantation of a port-catheter system in patients undergoing repeated hepatic arterial chemotherapy. , 2002, AJR. American journal of roentgenology.

[6]  T. Nishimura,et al.  Brain infarction after percutaneous implantation of port-catheter system via the left subclavian artery. , 2002, The British journal of radiology.

[7]  M. Salvioni,et al.  Percutaneous vs. surgical placement of hepatic artery indwelling catheters for regional chemotherapy. , 2002, Hepato-gastroenterology.

[8]  M. Reiser,et al.  Interventional radiological procedures in impaired function of surgically implanted catheter-port systems , 2001, CardioVascular and Interventional Radiology.

[9]  G. Gandini,et al.  Percutaneous implantation of a catheter with subcutaneous reservoir for intraarterial regional chemotherapy: Technique and preliminary results , 2000, CardioVascular and Interventional Radiology.

[10]  K. Sakai,et al.  Hepatic arterial infusion chemotherapy using percutaneous catheter placement with an implantable port: assessment of factors affecting patency of the hepatic artery. , 1999, Clinical radiology.

[11]  M. Tempero,et al.  Complications and technical limitations of hepatic arterial infusion catheter placement for chemotherapy. , 1998, Journal of vascular and interventional radiology : JVIR.

[12]  F. Wacker,et al.  Minimally invasive catheter implantation for regional chemotherapy of the liver: A new percutaneous transsubclavian approach , 1997, CardioVascular and Interventional Radiology.

[13]  E. Strecker,et al.  Percutaneously implantable catheter-port system: preliminary technical results. , 1997, Radiology.

[14]  D. Kerr,et al.  Is intra-arterial chemotherapy worthwhile in the treatment of patients with unresectable hepatic colorectal cancer metastases? , 1996, European journal of cancer.

[15]  M. Hori,et al.  Percutaneous implantation of hepatic artery infusion reservoir by sonographically guided left subclavian artery puncture. , 1996, AJR. American journal of roentgenology.

[16]  K. Abrams,et al.  Quality of life and survival with continuous hepatic-artery floxuridine infusion for colorectal liver metastases , 1994, The Lancet.

[17]  B. Levin,et al.  Gastric mucosal injury after hepatic arterial infusion chemotherapy with floxuridine. A clinical and pathologic study , 1994, Cancer.

[18]  K. Matsushita,et al.  [Complications and their management in intraarterial infusion chemotherapy]. , 1992, Gan to kagaku ryoho. Cancer & chemotherapy.

[19]  I. Huk,et al.  Patency Rate of Implantable Devices During Long-Term Intraaterial Chemotherapy , 1990, Angiology.

[20]  D. Kerr,et al.  A comparison of regional and systemic chemotherapy for hepatic metastases. , 1990, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[21]  M. Dürig,et al.  [Implantable catheter system for ambulatory parenteral antibiotic chemotherapy. A prospective study]. , 1989, Helvetica chirurgica acta.

[22]  A. Korn,et al.  Improved methods for venous access: the Port-A-Cath, a totally implanted catheter system. , 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  S. Wallace,et al.  Hepatic arterial redistribution for intraarterial infusion of hepatic neoplasms. , 1980, Radiology.

[24]  G. Wirtanen.  Percutaneous transbrachial artery infusion catheter techniques. , 1973, The American journal of roentgenology, radium therapy, and nuclear medicine.

[25]  G. Mitchell.  Blood Supply and Anatomy of the Upper Abdominal Organs , 1956 .

[26]  C. Breedis,et al.  The blood supply of neoplasms in the liver. , 1954, The American journal of pathology.

[27]  廣田 達哉.  Catheter redundancy in the aortic arch increases the risk of stroke in left subclavian arterial port-catheter systems , 2007 .

[28]  An-LongZhu,et al.  Liver regional continuous chemotherapy： Use of femoral or subclavian artery for percutaneous implantation of catheter-port systems , 2004 .