Comparison of Bioactivity Between GSM 900 MHz and DCS 1800 MHz Mobile Telephony Radiation

An increasing number of studies find that pulsed Radio Frequency (RF), electromagnetic radiation of both systems of digital mobile telephony, established and commonly used in Europe during the last years, GSM 900 MHz (Global System for Mobile telecommunications) and DCS 1800 MHz (Digital Cellular System), exert intense biological action on different organisms and cells (Hardell et al., 19; Hyland, 23; Kundi, 26; Panagopoulos et al., 4445). The two types of cellular telephony radiation use different carrier frequencies and give different frequency spectra, but they usually also differ in intensity, as GSM 900 MHz antennas operate at about double the power output than the corresponding DCS 1800 MHz ones. In our present experiments, we used a model biological system, the reproductive capacity of Drosophila melanogaster, to compare the biological activity between the two systems of cellular mobile telephony radiation. Both types of radiation were found to decrease significantly and non thermally the insect's reproductive capacity, but GSM 900 MHz seems to be even more bioactive than DCS 1800 MHz. The difference seems to be dependent mostly on field intensity and less on carrier frequency.

[1]  P. Raskmark,et al.  Changes in cell proliferation due to environmental non-ionizing radiation 1. ELF electromagnetic fields , 1995 .

[2]  M. Kundi,et al.  Mobile phone use and cancer , 2004, Occupational and Environmental Medicine.

[3]  E Cardis,et al.  Mobile phone use and risk of acoustic neuroma: results of the Interphone case–control study in five North European countries , 2005, British Journal of Cancer.

[4]  Martin Blank,et al.  Effects of mobile phone radiation on reproduction and development in Drosophila melanogaster , 2003, Journal of cellular biochemistry.

[5]  Dr. Yngve Hamnerius,et al.  Microwave Exposure from Mobile Phones and Base Stations in Sweden , 2001 .

[6]  J. Schimmelpfeng,et al.  The action of 50 Hz magnetic and electric fields upon cell proliferation and cyclic AMP content of cultured mammalian cells , 1993 .

[7]  W. R. Adey,et al.  Sensitivity of calcium binding in cerebral tissue to weak environmental electric fields oscillating at low frequency. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[8]  A. Ahlbom.  Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz) , 1998 .

[9]  W. R. Adey,et al.  EFFECTS OF MODULATED VHF FIELDS ON THE CENTRAL NERVOUS SYSTEM * , 1975, Annals of the New York Academy of Sciences.

[10]  A. Liboff,et al.  Time-varying magnetic fields: effect on DNA synthesis. , 1984, Science.

[11]  M Kundi,et al.  Subjective symptoms, sleeping problems, and cognitive performance in subjects living near mobile phone base stations , 2006, Occupational and Environmental Medicine.

[12]  D. Bilder,et al.  Mass transit: Epithelial morphogenesis in the Drosophila egg chamber , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[13]  M. T. Marron,et al.  Effects of electromagnetic fields on molecules and cells. , 1995, International review of cytology.

[14]  G. Rodan,et al.  DNA synthesis in cartilage cells is stimulated by oscillating electric fields. , 1978, Science.

[15]  Joachim Tisal.  GSM Cellular Radio Telephony , 1997 .

[16]  H. Lai,et al.  Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells. , 1995, Bioelectromagnetics.

[17]  R. Goodman,et al.  Exposure of salivary gland cells to low-frequency electromagnetic fields alters polypeptide synthesis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[18]  R. Aitken,et al.  Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline. , 2005, International journal of andrology.

[19]  D Krause,et al.  Role of modulation on the effect of microwaves on ornithine decarboxylase activity in L929 cells. , 1997, Bioelectromagnetics.

[20]  P Raskmark,et al.  The effects of radiofrequency fields on cell proliferation are non-thermal. , 1999, Bioelectrochemistry and bioenergetics.

[21]  W. R. Adey,et al.  Low frequency amplitude modulated microwave fields change calcium efflux rates from synaptosomes. , 1982, Bioelectromagnetics.

[22]  P. Raskmark,et al.  Changes in cell proliferation due to environmental non-ionizing radiation: 2. Microwave radiation , 1998 .

[23]  L. Margaritis,et al.  Stage-specific apoptotic patterns during Drosophila oogenesis. , 2000, European journal of cell biology.

[24]  Andreas Karabarbounis,et al.  Effect of GSM 900-MHz Mobile Phone Radiation on the Reproductive Capacity of Drosophila melanogaster , 2004 .

[25]  A. Spradling,et al.  Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. , 2001, Developmental biology.

[26]  Niels Kuster,et al.  Gene expression changes in human cells after exposure to mobile phone microwaves , 2006, Proteomics.

[27]  H. Lai,et al.  Single- and double-strand DNA breaks in rat brain cells after acute exposure to radiofrequency electromagnetic radiation. , 1996, International journal of radiation biology.

[28]  W. R. Adey,et al.  Ionic factors in release of 45Ca2+ from chicken cerebral tissue by electromagnetic fields. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Dimitris J. Panagopoulos,et al.  A mechanism for action of oscillating electric fields on cells. , 2000, Biochemical and biophysical research communications.

[30]  L. S. Kinney,et al.  Multiple power-density windows and their possible origin. , 1989, Bioelectromagnetics.

[31]  S. Dutta,et al.  Microwave radiation-induced calcium ion efflux from human neuroblastoma cells in culture. , 1984, Bioelectromagnetics.

[32]  J. Herbertz.  Comment on the ICNIRP guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz) , 1998, Health physics.

[33]  I. Magras,et al.  RF radiation-induced changes in the prenatal development of mice. , 1997, Bioelectromagnetics.

[34]  R. Goodman,et al.  Pulsing electromagnetic fields induce cellular transcription. , 1983, Science.

[35]  H. Lai,et al.  Acute exposure to a 60 Hz magnetic field increases DNA strand breaks in rat brain cells. , 1997, Bioelectromagnetics.

[36]  G. Hyland.  Physics and biology of mobile telephony , 2000, The Lancet.

[37]  J. Elder,et al.  Induction of calcium-ion efflux from brain tissue by radiofrequency radiation: effect of sample number and modulation frequency on the power-density window. , 1980, Bioelectromagnetics.

[38]  Dimitris J. Panagopoulos,et al.  Cell death induced by GSM 900-MHz and DCS 1800-MHz mobile telephony radiation. , 2007, Mutation research.

[39]  R. King.  Ovarian Development in Drosophila Melanogaster , 1970 .

[40]  M. Clark.  Networks and telecommunications , 1991 .

[41]  Lars Malmgren,et al.  Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. , 2003, Environmental health perspectives.

[42]  M. Barteri,et al.  Structural and kinetic effects of mobile phone microwaves on acetylcholinesterase activity. , 2005, Biophysical chemistry.

[43]  E. A. Navarro,et al.  The Microwave Syndrome: A Preliminary Study in Spain , 2003 .

[44]  Franz Adlkofer,et al.  Non-thermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro. , 2005, Mutation research.

[45]  Kjell Hansson Mild,et al.  Pooled analysis of two case–control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997–2003 , 2006, International archives of occupational and environmental health.

[46]  Dimitris J. Panagopoulos,et al.  Mechanism for action of electromagnetic fields on cells. , 2002, Biochemical and biophysical research communications.

[47]  Narendra Singh,et al.  Magnetic-field-induced DNA strand breaks in brain cells of the rat. , 2004, Environmental health perspectives.

[48]  Dariusz Leszczynski,et al.  Mobile phone radiation causes changes in gene and protein expression in human endothelial cell lines and the response seems to be genome‐ and proteome‐dependent , 2006, Proteomics.

[49]  W R Adey,et al.  Frequency dependence of increased cell proliferation, in vitro, in exposures to a low‐amplitude, low‐frequency electric field: Evidence for dependence on increased mitogen activity released into culture medium , 1989, Journal of cellular physiology.

[50]  Etsuko Abe,et al.  Electric fields stimulate DNA synthesis of mouse osteoblast‐like cells (MC3T3‐E1) by a mechanism involving calcium ions , 1989, Journal of cellular physiology.

[51]  Reilly Jp.  Comments concerning "Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz)". , 1999 .