Oxidative stress and vascular inflammation in aging.
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[1] S. Niture,et al. Regulation of Nrf2-an update. , 2014, Free radical biology & medicine.
[2] Kaitlyn N. Lewis,et al. The naked mole-rat response to oxidative stress: just deal with it. , 2013, Antioxidants & redox signaling.
[3] X. Cheng,et al. Impaired cross-activation of β3 integrin and VEGFR-2 on endothelial progenitor cells with aging decreases angiogenesis in response to hypoxia. , 2013, International journal of cardiology.
[4] W. Lamers,et al. Endothelium‐dependent hyperpolarization‐related relaxations diminish with age in murine saphenous arteries of both sexes , 2013, British journal of pharmacology.
[5] I. Boldogh,et al. Redox-regulating sirtuins in aging, caloric restriction, and exercise. , 2013, Free radical biology & medicine.
[6] M. Klonizakis,et al. Mediterranean diet- and exercise-induced improvement in age-dependent vascular activity. , 2013, Clinical science.
[7] Dolores Corella,et al. Primary prevention of cardiovascular disease with a Mediterranean diet. , 2013, The New England journal of medicine.
[8] M. Delp,et al. Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles. , 2013, Journal of applied physiology.
[9] B. Morris. Seven sirtuins for seven deadly diseases of aging. , 2013, Free radical biology & medicine.
[10] W. Park. The effects of exogenous H2O2 on cell death, reactive oxygen species and glutathione levels in calf pulmonary artery and human umbilical vein endothelial cells. , 2013, International journal of molecular medicine.
[11] E. Lakatta,et al. Bringing prevention in geriatrics: Evidences from cardiovascular medicine supporting the new challenge , 2013, Experimental Gerontology.
[12] S. Kintzios,et al. Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells , 2012, Neurochemistry International.
[13] Vincent Gremeaux,et al. Exercise and longevity. , 2012, Maturitas.
[14] F. Satterstrom,et al. From Sirtuin Biology to Human Diseases: An Update* , 2012, The Journal of Biological Chemistry.
[15] S. Kume,et al. Sirtuins and renal diseases: relationship with aging and diabetic nephropathy , 2012, Clinical science.
[16] J. Krieger,et al. Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats. , 2012, Atherosclerosis.
[17] L. Rodríguez-Mañas,et al. Age-related differences in the effects of α and γ peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels , 2012, Experimental Gerontology.
[18] E. Lakatta,et al. Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. , 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.
[19] P. Tucci. Caloric restriction: is mammalian life extension linked to p53? , 2012, Aging.
[20] L. Kublik,et al. Distribution of the activity of the angiotensin-converting enzyme in the rat aorta and changes in the activity with aging and by the action of l-NAME , 2012, AGE.
[21] A. Rivard,et al. Protection against vascular aging in Nox2-deficient mice: Impact on endothelial progenitor cells and reparative neovascularization. , 2012, Atherosclerosis.
[22] A. Gashev,et al. Evidence of increased oxidative stress in aged mesenteric lymphatic vessels. , 2012, Lymphatic research and biology.
[23] S. Kritchevsky,et al. Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. , 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.
[24] L. Rodríguez-Mañas,et al. Mechanisms Involved in the Aging-Induced Vascular Dysfunction , 2012, Front. Physio..
[25] F. Villarroya,et al. SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging. , 2012, The Biochemical journal.
[26] Kaitlyn N. Lewis,et al. Stress Resistance in the Naked Mole-Rat: The Bare Essentials – A Mini-Review , 2012, Gerontology.
[27] Elke M Sokoya,et al. Regulation of Cerebral Vascular Function by Sirtuin 1 , 2012, Microcirculation.
[28] M. Oellerich,et al. FOXOs and Sirtuins in Vascular Growth, Maintenance, and Aging , 2012, Circulation research.
[29] D. Sosnowska,et al. Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging , 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.
[30] Bradley S. Fleenor,et al. Superoxide‐lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice , 2012, Aging cell.
[31] Ryan A. Harris,et al. Acute Reversal of Endothelial Dysfunction in the Elderly After Antioxidant Consumption , 2012, Hypertension.
[32] K. Griendling,et al. Increased Expression of Nox1 in Neointimal Smooth Muscle Cells Promotes Activation of Matrix Metalloproteinase-9 , 2012, Journal of Vascular Research.
[33] M. Runge,et al. Mitochondrial Oxidative Stress in Aortic Stiffening With Age: The Role of Smooth Muscle Cell Function , 2012, Arteriosclerosis, thrombosis, and vascular biology.
[34] C. Auger,et al. Grape-Derived Polyphenols Improve Aging-Related Endothelial Dysfunction in Rat Mesenteric Artery: Role of Oxidative Stress and the Angiotensin System , 2012, PloS one.
[35] Sally E. Stringer,et al. Endothelial Progenitor Cells Enter the Aging Arena , 2012, Front. Physio..
[36] Y. Chi,et al. Aging-Shifted Prostaglandin Profile in Endothelium as a Factor in Cardiovascular Disorders , 2012, Journal of aging research.
[37] T. Asano,et al. Blockade of the Nuclear Factor-&kgr;B Pathway in the Endothelium Prevents Insulin Resistance and Prolongs Life Spans , 2012, Circulation.
[38] J. Tao,et al. Physical exercise attenuates age‐associated reduction in endothelium‐reparative capacity of endothelial progenitor cells by increasing CXCR4/JAK‐2 signaling in healthy men , 2012, Aging cell.
[39] Yikyung Park,et al. Amount of time spent in sedentary behaviors and cause-specific mortality in US adults. , 2012, The American journal of clinical nutrition.
[40] N. Toda. Age-related changes in endothelial function and blood flow regulation. , 2012, Pharmacology & therapeutics.
[41] R. Tostes,et al. Differential Modulation of Nitric Oxide Synthases in Aging: Therapeutic Opportunities , 2012, Front. Physio..
[42] Patty J. Lee,et al. Aging Enhances the Basal Production of IL-6 and CCL2 in Vascular Smooth Muscle Cells , 2012, Arteriosclerosis, thrombosis, and vascular biology.
[43] Fanjie Meng,et al. STAT1 mediates cellular senescence induced by angiotensin II and H2O2 in human glomerular mesangial cells , 2011, Molecular and Cellular Biochemistry.
[44] D. Crocker,et al. Apnea stimulates the adaptive response to oxidative stress in elephant seal pups , 2011, Journal of Experimental Biology.
[45] G. Pierce,et al. Habitually exercising older men do not demonstrate age‐associated vascular endothelial oxidative stress , 2011, Aging cell.
[46] H. H. Marti,et al. Impaired hypoxic response in senescent mouse brain , 2011, International Journal of Developmental Neuroscience.
[47] S. Dikalov. Cross talk between mitochondria and NADPH oxidases. , 2011, Free radical biology & medicine.
[48] P. Jat,et al. Deciphering the role of Nuclear Factor-κB in cellular senescence , 2011, Aging.
[49] D. Seals,et al. SIRT‐1 and vascular endothelial dysfunction with ageing in mice and humans , 2011, The Journal of physiology.
[50] T. Byzova,et al. Oxidation as “The Stress of Life” , 2011, Aging.
[51] Douglas R Seals,et al. Aerobic exercise reverses arterial inflammation with aging in mice. , 2011, American journal of physiology. Heart and circulatory physiology.
[52] D. Bennett,et al. Vascular Contributions to Cognitive Impairment and Dementia: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association , 2011, Stroke.
[53] A. Rivard,et al. Accelerated Vascular Aging in CuZnSOD-Deficient Mice: Impact on EPC Function and Reparative Neovascularization , 2011, PloS one.
[54] M. F. Ladelfa,et al. Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production. , 2011, Antioxidants & redox signaling.
[55] R. de Cabo,et al. Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. , 2011, American journal of physiology. Heart and circulatory physiology.
[56] Peter M. Nilsson,et al. Microvascular brain damage with aging and hypertension: pathophysiological consideration and clinical implications , 2011, Journal of hypertension.
[57] E. Lakatta,et al. Age‐associated vascular oxidative stress, Nrf2 dysfunction and NF‐κB activation in the non‐human primate Macaca mulatta , 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.
[58] X. Hou,et al. Angiotensin II modulates interleukin-1β-induced inflammatory gene expression in vascular smooth muscle cells via interfering with ERK-NF-κB crosstalk. , 2011, Biochemical and biophysical research communications.
[59] Nektarios Tavernarakis,et al. Cellular stress response pathways and ageing: intricate molecular relationships , 2011, The EMBO journal.
[60] S. Leonard,et al. Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice. , 2011, Free radical biology & medicine.
[61] A. Wojtovich,et al. Redox regulation of the mitochondrial K(ATP) channel in cardioprotection. , 2011, Biochimica et biophysica acta.
[62] Min Zhang,et al. Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo , 2011, Free radical biology & medicine.
[63] S. Reddy,et al. Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter. , 2011, Free radical biology & medicine.
[64] M. Fuente,et al. Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice , 2011, Journal of Physiology and Biochemistry.
[65] M. Jackson,et al. Age‐related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species , 2011, The Journal of physiology.
[66] J. Montani,et al. Hyperactive S6K1 Mediates Oxidative Stress and Endothelial Dysfunction in Aging: Inhibition by Resveratrol , 2011, PloS one.
[67] G. Nickenig,et al. Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase , 2011, Basic Research in Cardiology.
[68] K. Shinmura. Cardiovascular protection afforded by caloric restriction: Essential role of nitric oxide synthase , 2011, Geriatrics & gerontology international.
[69] M. Kaeberlein,et al. HIF‐1 modulates longevity and healthspan in a temperature‐dependent manner , 2011, Aging cell.
[70] D. Schlessinger,et al. Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA Study. , 2011, Atherosclerosis.
[71] P. Pardo,et al. The physiological roles of Sirt1 in skeletal muscle , 2011, Aging.
[72] P. Pandolfi,et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. , 2011, Cancer cell.
[73] A. Shah,et al. The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4* , 2011, The Journal of Biological Chemistry.
[74] E. Lakatta,et al. A Local Proinflammatory Signalling Loop Facilitates Adverse Age-Associated Arterial Remodeling , 2011, PloS one.
[75] S. Dimmeler,et al. Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells. , 2011, European heart journal.
[76] C. Auger,et al. Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase. , 2011, Biochemical and biophysical research communications.
[77] Meredith J. Luttrell,et al. NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries. , 2011, Journal of applied physiology.
[78] A. Samuelson,et al. The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation , 2011, Current opinion in clinical nutrition and metabolic care.
[79] A. Csiszar. Anti‐inflammatory effects of resveratrol: possible role in prevention of age‐related cardiovascular disease , 2011, Annals of the New York Academy of Sciences.
[80] Seung-Jae V. Lee,et al. Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity , 2010, Current Biology.
[81] Danica Chen,et al. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. , 2010, Cell metabolism.
[82] M. Jackson,et al. The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase , 2010, Aging cell.
[83] Kaitlyn N. Lewis,et al. Nrf2, a guardian of healthspan and gatekeeper of species longevity. , 2010, Integrative and comparative biology.
[84] M. Stebel,et al. Caloric restriction improves endothelial dysfunction during vascular aging: Effects on nitric oxide synthase isoforms and oxidative stress in rat aorta , 2010, Experimental Gerontology.
[85] W. Wong,et al. Hypoxia-inducible factors and the response to hypoxic stress. , 2010, Molecular cell.
[86] Shih-Jen Chen,et al. Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation. , 2010, Journal of atherosclerosis and thrombosis.
[87] C. Giannarelli,et al. Endothelial dysfunction and vascular disease in later life. , 2010, Maturitas.
[88] Z. Ungvari,et al. Mitochondria and aging in the vascular system , 2010, Journal of Molecular Medicine.
[89] K. Okumura,et al. Exercise Training Stimulates Ischemia-Induced Neovascularization via Phosphatidylinositol 3-Kinase/Akt-Dependent Hypoxia-Induced Factor-1&agr; Reactivation in Mice of Advanced Age , 2010, Circulation.
[90] T. Murphy,et al. PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B. , 2010, American journal of physiology. Lung cellular and molecular physiology.
[91] G. Remuzzi,et al. Angiotensin II revisited: new roles in inflammation, immunology and aging , 2010, EMBO molecular medicine.
[92] R. de Cabo,et al. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2 , 2010, American journal of physiology. Heart and circulatory physiology.
[93] A. Petry,et al. The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1 , 2010, Molecular biology of the cell.
[94] D. Seals,et al. Short‐term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress , 2010, Aging cell.
[95] H. Weiss,et al. Hypoxia‐inducible factor‐1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity , 2010, Experimental physiology.
[96] S. Hekimi,et al. Lifelong protection from global cerebral ischemia and reperfusion in long-lived Mclk1 +/ − mutants , 2010, Experimental Neurology.
[97] M. Hassan,et al. Exercise training attenuates ageing‐induced BKCa channel downregulation in rat coronary arteries , 2010, Experimental physiology.
[98] E. Gottlieb,et al. p53 regulation of metabolic pathways. , 2010, Cold Spring Harbor perspectives in biology.
[99] D. Harrison,et al. Therapeutic targeting of mitochondrial superoxide in hypertension , 2010, Circulation research.
[100] K. Griendling,et al. NADPH Oxidases: Functions and Pathologies in the Vasculature , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[101] G. Pierce,et al. Vascular Endothelial Function Is Related to White Blood Cell Count and Myeloperoxidase Among Healthy Middle-Aged and Older Adults , 2010, Hypertension.
[102] D. Bailey,et al. Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men. , 2010, American journal of physiology. Heart and circulatory physiology.
[103] Z. Ungvari,et al. Oxidative Stress and Endothelial Dysfunction in Pulmonary Arteries of Aged Rats , 2010, American journal of physiology. Heart and circulatory physiology.
[104] Orian S. Shirihai,et al. The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α , 2010, Cell.
[105] M. Driscoll,et al. Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1 , 2010, PloS one.
[106] M. Joyner,et al. Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells. , 2009, Microvascular research.
[107] G. Pierce,et al. Habitual exercise and vascular ageing , 2009, The Journal of physiology.
[108] Nupura S. Bhise,et al. Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia , 2009, Proceedings of the National Academy of Sciences.
[109] H. Bohlen,et al. Abnormal nitric oxide production in aged rat mesenteric arteries is mediated by NAD(P)H oxidase-derived peroxide. , 2009, American journal of physiology. Heart and circulatory physiology.
[110] Qun Gao,et al. Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase. , 2009, American journal of physiology. Heart and circulatory physiology.
[111] A. Shoukas,et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. , 2009, Journal of applied physiology.
[112] Yang-ming Yang,et al. eNOS uncoupling and endothelial dysfunction in aged vessels. , 2009, American journal of physiology. Heart and circulatory physiology.
[113] D. S. St. Clair,et al. Regulation of superoxide dismutase genes: implications in disease. , 2009, Free radical biology & medicine.
[114] K. Pearson,et al. Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1 , 2009, Mechanisms of Ageing and Development.
[115] Dean P. Jones,et al. Attenuation of Angiotensin II–Induced Vascular Dysfunction and Hypertension by Overexpression of Thioredoxin 2 , 2009, Hypertension.
[116] Stéphane Laurent,et al. Large and small artery cross-talk and recent morbidity-mortality trials in hypertension. , 2009, Hypertension.
[117] Z. Zhai,et al. The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans , 2009, PloS one.
[118] J. LaManna,et al. Increased prolyl 4-hydroxylase expression and differential regulation of hypoxia-inducible factors in the aged rat brain. , 2009, American journal of physiology. Regulatory, integrative and comparative physiology.
[119] D. Seals,et al. Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. , 2009, American journal of physiology. Heart and circulatory physiology.
[120] D. Seals,et al. Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down‐regulation of NADPH oxidase , 2009, The Journal of physiology.
[121] D. Heistad,et al. Protective effect of extracellular superoxide dismutase on endothelial function during aging. , 2009, American journal of physiology. Heart and circulatory physiology.
[122] L. Rodríguez-Mañas,et al. Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation , 2009, Aging cell.
[123] M. Joyner,et al. Aging Is Associated With Reduced Prostacyclin-Mediated Dilation in the Human Forearm , 2009, Hypertension.
[124] P. Pelicci,et al. P66Shc signals to age , 2009, Aging.
[125] Y. Sasaguri,et al. Nitric Oxide Synthases and Cardiovascular Diseases , 2009 .
[126] P. Kapahi,et al. HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans , 2009, PLoS genetics.
[127] Toshiko Tanaka,et al. COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan , 2009, Circulation. Cardiovascular genetics.
[128] Dan Yang,et al. Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy , 2009, Cell cycle.
[129] S. Beske,et al. Nuclear Factor-&kgr;B Activation Contributes to Vascular Endothelial Dysfunction via Oxidative Stress in Overweight/Obese Middle-Aged and Older Humans , 2009, Circulation.
[130] G. Remuzzi,et al. Disruption of the Ang II type 1 receptor promotes longevity in mice. , 2009, The Journal of clinical investigation.
[131] S. Schildknecht,et al. Signalling processes in endothelial ageing in relation to chronic oxidative stress and their potential therapeutic implications in humans , 2009, Experimental physiology.
[132] M. Wolin. Reactive oxygen species and the control of vascular function. , 2009, American journal of physiology. Heart and circulatory physiology.
[133] S. Anton,et al. Molecular inflammation: Underpinnings of aging and age-related diseases , 2009, Ageing Research Reviews.
[134] Howard Y. Chang,et al. SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span , 2009, Cell.
[135] A. LeBlanc,et al. Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles. , 2008, American journal of physiology. Heart and circulatory physiology.
[136] F. Sellke,et al. Decreased vascular repair and neovascularization with ageing: mechanisms and clinical relevance with an emphasis on hypoxia-inducible factor-1. , 2008, Current molecular medicine.
[137] D. Harrison,et al. Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease. , 2008, Journal of the American College of Cardiology.
[138] Y. Ho,et al. Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells. , 2008, Free radical biology & medicine.
[139] P. Vanhoutte,et al. Endothelium‐dependent contractions: when a good guy turns bad! , 2008, The Journal of physiology.
[140] T. Kawamoto,et al. Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. , 2008, Cardiovascular research.
[141] D. Christianson,et al. Arginase and vascular aging. , 2008, Journal of applied physiology.
[142] T. Lüscher,et al. The role of p66Shc deletion in age-associated arterial dysfunction and disease states. , 2008, Journal of applied physiology.
[143] D. Harrison,et al. Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. , 2008, Free radical biology & medicine.
[144] L. Raij,et al. The angiotensin II type 2 receptor: What is its clinical significance? , 2008, Current hypertension reports.
[145] E. Lakatta,et al. Inflammation and endothelial dysfunction during aging: role of NF-kappaB. , 2008, Journal of applied physiology.
[146] Leonid Peshkin,et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. , 2008, Cell metabolism.
[147] Paul J Thornalley,et al. Activation of NF-E2–Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease , 2008, Diabetes.
[148] W. Welch. Angiotensin II-dependent superoxide: effects on hypertension and vascular dysfunction. , 2008, Hypertension.
[149] S. Mohr,et al. Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators , 2008, Diabetes.
[150] E. Schiffrin,et al. Role of the renin-angiotensin system in vascular inflammation. , 2008, Trends in pharmacological sciences.
[151] K. Sunagawa,et al. SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[152] A. Scuteri,et al. Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome. , 2008, Nutrition, metabolism, and cardiovascular diseases : NMCD.
[153] J. Curb,et al. Antioxidants in cardiovascular health and disease: key lessons from epidemiologic studies. , 2008, The American journal of cardiology.
[154] Jing Zhang,et al. Increased Aortic Calpain-1 Activity Mediates Age-Associated Angiotensin II Signaling of Vascular Smooth Muscle Cells , 2008, PloS one.
[155] W. Mayhan,et al. Losartan improves impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type 1 diabetic rats , 2008, Brain Research.
[156] N. Ishii,et al. Hyperoxia exposure induced hormesis decreases mitochondrial superoxide radical levels via Ins/IGF-1 signaling pathway in a long-lived age-1 mutant of Caenorhabditis elegans. , 2008, Journal of radiation research.
[157] Z. Ungvari,et al. Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. , 2008, American journal of physiology. Heart and circulatory physiology.
[158] J. Qu,et al. NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK. , 2008, Biochimica et biophysica acta.
[159] T. Suuronen,et al. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging , 2008, Ageing Research Reviews.
[160] T. Lüscher,et al. Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein. , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[161] Jennifer M. A. Tullet,et al. Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans , 2008, Cell.
[162] R. de Cabo,et al. Mechanisms Underlying Caloric Restriction and Lifespan Regulation: Implications for Vascular Aging , 2008, Circulation research.
[163] C. Thompson,et al. Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney Dysfunction , 2008, Journal of Vascular Research.
[164] Chih‐Chung Lin,et al. Lipoteichoic Acid Induces HO-1 Expression via the TLR2/MyD88/c-Src/NADPH Oxidase Pathway and Nrf2 in Human Tracheal Smooth Muscle Cells1 , 2008, The Journal of Immunology.
[165] J. Sowers,et al. Role of mitochondrial dysfunction in insulin resistance. , 2008, Circulation research.
[166] Joy W. Chang,et al. Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction , 2008, Proceedings of the National Academy of Sciences.
[167] S. Ghosh,et al. Shared Principles in NF-κB Signaling , 2008, Cell.
[168] F. Dowell,et al. Differential effects of glucose on agonist‐induced relaxations in human mesenteric and subcutaneous arteries , 2008, British journal of pharmacology.
[169] P. Vanhoutte,et al. Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats , 2008, Acta Pharmacologica Sinica.
[170] Guoyao Wu,et al. Ageing diminishes endothelium‐dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles , 2008, The Journal of physiology.
[171] S. Rohrbach,et al. Caloric restriction counteracts age-dependent changes in prolyl-4-hydroxylase domain (PHD) 3 expression , 2008, Biogerontology.
[172] Eran Segal,et al. Motif module map reveals enforcement of aging by continual NF-κB activity , 2007 .
[173] A. Giaccia,et al. Age Decreases Endothelial Progenitor Cell Recruitment Through Decreases in Hypoxia-Inducible Factor 1α Stabilization During Ischemia , 2007, Circulation.
[174] G. Semenza,et al. Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia , 2007, Circulation research.
[175] C. Franceschi. Inflammaging as a major characteristic of old people: can it be prevented or cured? , 2007, Nutrition reviews.
[176] S. Austad,et al. Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity , 2007, Aging cell.
[177] Maylis Tartas,et al. Endothelium‐derived hyperpolarizing factor as an in vivo back‐up mechanism in the cutaneous microcirculation in old mice , 2007, The Journal of physiology.
[178] D. Grobbee,et al. C-reactive protein and aortic stiffness and wave reflection in middle-aged and elderly men from the community , 2007, Journal of Human Hypertension.
[179] P. Schroeder,et al. Nuclear Redox-Signaling Is Essential for Apoptosis Inhibition in Endothelial Cells—Important Role for Nuclear Thioredoxin-1 , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[180] D. Seals,et al. High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men. , 2007, Journal of applied physiology.
[181] D. Harrison,et al. Abstract 1229: Molecular Mechanisms of Angiotensin II-Mediated Mitochondrial Dysfunction: Linking Mitochondrial Oxidative Damage and Vascular Endothelial Dysfunction , 2007 .
[182] A. J. Lambert,et al. Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms , 2007, Aging cell.
[183] A. Shoukas,et al. Inducible NO Synthase–Dependent S-Nitrosylation and Activation of Arginase1 Contribute to Age-Related Endothelial Dysfunction , 2007, Circulation research.
[184] Cuk-Seong Kim,et al. SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase , 2007, Proceedings of the National Academy of Sciences.
[185] J. Roselló-Catafau,et al. Loss of adaptation to oxidative stress as a mechanism for aortic damage in aging rats , 2007, Journal of Physiology and Biochemistry.
[186] F. Faraci,et al. Effect of Aging, MnSOD Deficiency, and Genetic Background on Endothelial Function: Evidence for MnSOD Haploinsufficiency , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[187] F. Inserra,et al. From Mitochondria to Disease: Role of the Renin-Angiotensin System , 2007, American Journal of Nephrology.
[188] Csaba Szabó,et al. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics , 2007, Nature Reviews Drug Discovery.
[189] M. Björkholm,et al. The Opposing Effect of Hypoxia-Inducible Factor-2α on Expression of Telomerase Reverse Transcriptase , 2007, Molecular Cancer Research.
[190] R. Virmani,et al. Proinflammatory Profile Within the Grossly Normal Aged Human Aortic Wall , 2007, Hypertension.
[191] Z. Ungvari,et al. Increased mitochondrial H2O2 production promotes endothelial NF-κB activation in aged rat arteries , 2007 .
[192] Paul T. Schumacker,et al. Mitochondrial Reactive Oxygen Species Trigger Hypoxia-Inducible Factor-Dependent Extension of the Replicative Life Span during Hypoxia , 2007, Molecular and Cellular Biology.
[193] G. Pierce,et al. Direct Evidence of Endothelial Oxidative Stress With Aging in Humans: Relation to Impaired Endothelium-Dependent Dilation and Upregulation of Nuclear Factor-&kgr;B , 2007, Circulation research.
[194] Qun Gao,et al. Aging enhances pressure-induced arterial superoxide formation. , 2007, American journal of physiology. Heart and circulatory physiology.
[195] L. Guarente,et al. Two neurons mediate diet-restriction-induced longevity in C. elegans , 2007, Nature.
[196] S. Cregan,et al. Extension of Human Cell Lifespan by Nicotinamide Phosphoribosyltransferase* , 2007, Journal of Biological Chemistry.
[197] Karl-Heinz Krause,et al. Aging: A revisited theory based on free radicals generated by NOX family NADPH oxidases , 2007, Experimental Gerontology.
[198] L. Hayflick. Biological Aging Is No Longer an Unsolved Problem , 2007, Annals of the New York Academy of Sciences.
[199] G. Yen,et al. Differential expressions of antioxidant status in aging rats: the role of transcriptional factor Nrf2 and MAPK signaling pathway , 2007, Biogerontology.
[200] Christian Gluud,et al. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. , 2007, JAMA.
[201] S. Baek,et al. Phosphatidic acid as a regulator of matrix metalloproteinase‐9 expression via the TNF‐α signaling pathway , 2007, FEBS letters.
[202] P. Poole‐Wilson,et al. Age-Dependent Impairment of Endothelial Progenitor Cells Is Corrected by Growth Hormone Mediated Increase of Insulin-Like Growth Factor-1 , 2007, Circulation research.
[203] M. Joyner,et al. Ageing reduces nitric‐oxide‐ and prostaglandin‐mediated vasodilatation in exercising humans , 2007, The Journal of physiology.
[204] T. Kodama,et al. Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species. , 2007, Free radical biology & medicine.
[205] J. Sastre,et al. Age-related increase in xanthine oxidase activity in human plasma and rat tissues , 2007, Free radical research.
[206] L. Rodríguez-Mañas,et al. Pro‐inflammatory effects of early non‐enzymatic glycated proteins in human mesothelial cells vary with cell donor's age , 2006, British journal of pharmacology.
[207] Z. Ungvari,et al. Comparison of endothelial function, O2.‐ and H2O2 production and vascular oxidative stress resistance between the longest‐living rodent, the naked mole‐rat and mice , 2006, American journal of physiology. Heart and circulatory physiology.
[208] F. Faraci,et al. Heterozygous CuZn Superoxide Dismutase Deficiency Produces a Vascular Phenotype With Aging , 2006, Hypertension.
[209] Lacy A. Holowatz,et al. Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin. , 2006, American journal of physiology. Heart and circulatory physiology.
[210] A. Shoukas,et al. Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness. , 2006, Journal of applied physiology.
[211] L. Ignarro,et al. Endothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetes , 2006, Proceedings of the National Academy of Sciences.
[212] F. McArdle,et al. Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age , 2006, Mechanisms of Ageing and Development.
[213] R. Brook,et al. Angiotensin Receptor Blockade Improves Vascular Compliance in Healthy Normotensive Elderly Individuals: Results From a Randomized Double‐Blind Placebo‐Controlled Trial , 2006, Journal of clinical hypertension.
[214] J. Feely,et al. Collagen type-I degradation is related to arterial stiffness in hypertensive and normotensive subjects , 2006, Journal of Human Hypertension.
[215] Stephen Scott,et al. Vascular smooth muscle cell senescence in atherosclerosis. , 2006, Cardiovascular research.
[216] S. Ghosh,et al. NF-κB and the immune response , 2006, Oncogene.
[217] S. Neubauer,et al. 5-Methyltetrahydrofolate Rapidly Improves Endothelial Function and Decreases Superoxide Production in Human Vessels: Effects on Vascular Tetrahydrobiopterin Availability and Endothelial Nitric Oxide Synthase Coupling , 2006, Circulation.
[218] Z. Yousefipour,et al. Oxidative Stress-Associated Vascular Aging Is Xanthine Oxidase-Dependent but not NAD(P)H Oxidase-Dependent , 2006, Journal of cardiovascular pharmacology.
[219] D. Harrison,et al. Early determinants of H2O2-induced endothelial dysfunction. , 2006, Free radical biology & medicine.
[220] D. Shih,et al. Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice. , 2006, Life sciences.
[221] D. Hajjar,et al. Oxidative alterations of cyclooxygenase during atherogenesis. , 2006, Prostaglandins & other lipid mediators.
[222] W. L. Kenney,et al. l‐Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin , 2006, The Journal of physiology.
[223] L. Rochette,et al. NADPH oxidases are in part responsible for increased cardiovascular superoxide production during aging. , 2006, Free radical biology & medicine.
[224] K. Chayama,et al. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production. , 2006, Atherosclerosis.
[225] H. Chung,et al. The molecular inflammatory process in aging. , 2006, Antioxidants & redox signaling.
[226] K. Moreau,et al. Modulatory influences on ageing of the vasculature in healthy humans , 2006, Experimental Gerontology.
[227] H. Chung,et al. Adaptive mechanisms to oxidative stress during aging , 2006, Mechanisms of Ageing and Development.
[228] U. Förstermann,et al. Endothelial Nitric Oxide Synthase in Vascular Disease: From Marvel to Menace , 2006, Circulation.
[229] J. Falck,et al. ROS‐sensitive cytochrome P450 activity maintains endothelial dilatation in ageing but is transitory in dyslipidaemic mice , 2006, British journal of pharmacology.
[230] L. Ghiadoni,et al. Endothelium, aging, and hypertension , 2006, Current hypertension reports.
[231] S. Davidge,et al. Age-associated impairment in vasorelaxation to fluid shear stress in the female vasculature is improved by TNF-alpha antagonism. , 2006, American journal of physiology. Heart and circulatory physiology.
[232] D. Seals,et al. Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium‐dependent dilatation with ageing , 2006, The Journal of physiology.
[233] Z. Yang,et al. Circulating endothelial progenitor cell deficiency contributes to impaired arterial elasticity in persons of advancing age , 2006, Journal of Human Hypertension.
[234] G. Caimi,et al. Impaired plasma nitric oxide availability and extracellular superoxide dismutase activity in healthy humans with advancing age. , 2006, Life sciences.
[235] Bertrand Friguet,et al. The ubiquitin–proteasome system at the crossroads of stress-response and ageing pathways: A handle for skin care? , 2006, Ageing Research Reviews.
[236] A. Shoukas,et al. Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats , 2006, Hypertension.
[237] L. Rodríguez-Mañas,et al. Changes in the human peritoneal mesothelial cells during aging. , 2006, Kidney international.
[238] T. Yamamori,et al. P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction. , 2005, Journal of molecular and cellular cardiology.
[239] Ramaroson Andriantsitohaina,et al. Improvement of age‐related endothelial dysfunction by simvastatin: effect on NO and COX pathways , 2005, British journal of pharmacology.
[240] L. Truong,et al. Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging. , 2005, Kidney international.
[241] Emilio Clementi,et al. Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS , 2005, Science.
[242] E. Schwedhelm,et al. Determination of a reference value for NG, NG‐dimethyl‐L‐arginine in 500 subjects , 2005, European journal of clinical investigation.
[243] J. Giraldo,et al. Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries. , 2005, Autonomic & autacoid pharmacology.
[244] Edward G Lakatta,et al. Arterial aging: is it an immutable cardiovascular risk factor? , 2005, Hypertension.
[245] L. Rodríguez-Mañas,et al. Amadori adducts activate nuclear factor‐κB‐related proinflammatory genes in cultured human peritoneal mesothelial cells , 2005, British journal of pharmacology.
[246] C. Franceschi,et al. p66 shc is highly expressed in fibroblasts from centenarians , 2005, Mechanisms of Ageing and Development.
[247] P. Pelicci,et al. Genetic Deletion of the p66Shc Adaptor Protein Protects From Angiotensin II–Induced Myocardial Damage , 2005, Hypertension.
[248] A. Kong,et al. Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells , 2005, Oncogene.
[249] M. Kelm,et al. Impaired progenitor cell activity in age-related endothelial dysfunction. , 2005, Journal of the American College of Cardiology.
[250] S. Bode-Böger,et al. Asymmetric dimethylarginine (ADMA) accelerates cell senescence , 2005, Vascular medicine.
[251] E. Lakatta,et al. Aging hearts and vessels: masters of adaptation and survival. , 2005, Cardiovascular research.
[252] L. Ghiadoni,et al. Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men. , 2005, American journal of hypertension.
[253] J. Babraj,et al. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[254] E. Vila,et al. Cytokines and vascular reactivity in resistance arteries. , 2005, American journal of physiology. Heart and circulatory physiology.
[255] B. Kalyanaraman,et al. Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP? , 2005, Free radical biology & medicine.
[256] S. Taddei,et al. Endothelium‐dependent contractions in hypertension , 2005, British journal of pharmacology.
[257] Leslie A. Smith,et al. Mechanisms of aging-induced impairment of endothelium-dependent relaxation: role of tetrahydrobiopterin. , 2004, American journal of physiology. Heart and circulatory physiology.
[258] Z. Ungvari,et al. Vascular Inflammation in Aging , 2004, Herz.
[259] S. Reddy,et al. NADPH Oxidase and ERK Signaling Regulates Hyperoxia-induced Nrf2-ARE Transcriptional Response in Pulmonary Epithelial Cells* , 2004, Journal of Biological Chemistry.
[260] H. Chung,et al. Vascular aging: molecular modulation of the prostanoid cascade by calorie restriction. , 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.
[261] A. Hofman,et al. C-reactive protein and arterial stiffness in older adults: the Rotterdam Study. , 2004, Atherosclerosis.
[262] M. Iida,et al. Changes in endothelium‐derived hyperpolarizing factor in hypertension and ageing: response to chronic treatment with renin–angiotensin system inhibitors , 2004, Clinical and experimental pharmacology & physiology.
[263] F. Faraci,et al. Vascular protection: superoxide dismutase isoforms in the vessel wall. , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[264] M. Mayo,et al. Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase , 2004, The EMBO journal.
[265] T. Oury,et al. Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats. , 2004, American journal of physiology. Heart and circulatory physiology.
[266] D. Seals,et al. Effect of acute and chronic ascorbic acid on flow‐mediated dilatation with sedentary and physically active human ageing , 2004, The Journal of physiology.
[267] A. Kong,et al. Modulatory Properties of Various Natural Chemopreventive Agents on the Activation of NF-κB Signaling Pathway , 2004, Pharmaceutical Research.
[268] K. Griendling,et al. Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[269] Steven P. Gygi,et al. Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase , 2004, Science.
[270] Z. Ungvari,et al. Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. , 2004, Physiological genomics.
[271] H. Chung,et al. Alteration of soluble adhesion molecules during aging and their modulation by calorie restriction , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[272] D. Kaye,et al. An age-related decline in endothelial function is not associated with alterations in l-arginine transport in humans , 2004, Journal of hypertension.
[273] I. Fridovich. Mitochondria: are they the seat of senescence? , 2004, Aging cell.
[274] S. Ibayashi,et al. Nox4 as the Major Catalytic Component of an Endothelial NAD(P)H Oxidase , 2004, Circulation.
[275] R. Touyz. Activated oxygen metabolites: do they really play a role in angiotensin II-regulated vascular tone? , 2003, Journal of hypertension.
[276] E. Breeze,et al. Antioxidant vitamins and mortality in older persons: findings from the nutrition add-on study to the Medical Research Council Trial of Assessment and Management of Older People in the Community. , 2003, The American journal of clinical nutrition.
[277] A. Shoukas,et al. Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels , 2003, Circulation.
[278] M. Reed,et al. Aging and angiogenesis. , 2003, Frontiers in bioscience : a journal and virtual library.
[279] E. Topol,et al. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials , 2003, The Lancet.
[280] E. Lakatta,et al. Aging Increases Aortic MMP‐2 Activity and Angiotensin II in Nonhuman Primates , 2003, Hypertension.
[281] Z. Ungvari,et al. Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteries , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[282] M. Levrero,et al. Endothelial activation by angiotensin II through NFκB and p38 pathways: Involvement of NFκB‐inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin , 2003, Journal of cellular physiology.
[283] P. Cuevas,et al. Calcium dobesilate potentiates endothelium‐derived hyperpolarizing factor‐mediated relaxation of human penile resistance arteries , 2003, British journal of pharmacology.
[284] R. Touyz. Reactive oxygen species in vascular biology: role in arterial hypertension , 2003, Expert review of cardiovascular therapy.
[285] G. Brabant,et al. Oral L-arginine improves endothelial function in healthy individuals older than 70 years , 2003, Vascular medicine.
[286] Steven M Holland,et al. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. , 2003, The Journal of clinical investigation.
[287] T. Lüscher,et al. Deletion of p66shc Gene Protects Against Age-Related Endothelial Dysfunction , 2003, Circulation.
[288] Gabor Kaley,et al. Increased Superoxide Production in Coronary Arteries in Hyperhomocysteinemia: Role of Tumor Necrosis Factor-&agr;, NAD(P)H Oxidase, and Inducible Nitric Oxide Synthase , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[289] Daniel Levy,et al. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. , 2003, Circulation.
[290] J. Remacle,et al. Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts. , 2002, Free radical biology & medicine.
[291] E. Dere,et al. Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open‐field habituation and alterations in forebrain neurotransmitter levels , 2002, Genes, brain, and behavior.
[292] P. Taylor,et al. Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects. , 2002, Cardiovascular research.
[293] A. Takeshita,et al. Inhibition of Renin-Angiotensin System Ameliorates Endothelial Dysfunction Associated With Aging in Rats , 2002, Arteriosclerosis, thrombosis, and vascular biology.
[294] Z. Ungvari,et al. Aging-Induced Phenotypic Changes and Oxidative Stress Impair Coronary Arteriolar Function , 2002, Circulation research.
[295] E. Schiffrin,et al. Expression of a Functionally Active gp91phox-Containing Neutrophil-Type NAD(P)H Oxidase in Smooth Muscle Cells From Human Resistance Arteries: Regulation by Angiotensin II , 2002, Circulation research.
[296] Anne McArdle,et al. Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity , 2002, Muscle & nerve.
[297] K. Channon,et al. Mechanisms of Increased Vascular Superoxide Production in Human Diabetes Mellitus: Role of NAD(P)H Oxidase and Endothelial Nitric Oxide Synthase , 2002, Circulation.
[298] E. Lakatta,et al. Altered Regulation of Matrix Metalloproteinase-2 in Aortic Remodeling During Aging , 2002, Hypertension.
[299] C. Giardina,et al. Growing old with nuclear factor–κB , 2002, Cell stress & chaperones.
[300] M. Iida,et al. Angiotensin II receptor antagonist improves age-related endothelial dysfunction , 2002, Journal of hypertension.
[301] S. Rajagopalan,et al. Effect of losartan in aging-related endothelial impairment. , 2002, The American journal of cardiology.
[302] K. Webster,et al. Oxidation of zinc finger transcription factors: physiological consequences. , 2001, Antioxidants & redox signaling.
[303] D. Stuehr,et al. Oxygen Reduction by Nitric-oxide Synthases* , 2001, The Journal of Biological Chemistry.
[304] D. Harrison,et al. Endothelial Regulation of Vasomotion in ApoE-Deficient Mice: Implications for Interactions Between Peroxynitrite and Tetrahydrobiopterin , 2001, Circulation.
[305] A. Dominiczak,et al. Superoxide Excess in Hypertension and Aging: A Common Cause of Endothelial Dysfunction , 2001, Hypertension.
[306] T. Lüscher,et al. Enhanced Peroxynitrite Formation Is Associated with Vascular Aging , 2000, The Journal of experimental medicine.
[307] D. Harrison,et al. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. , 2000, Circulation research.
[308] A. Habib,et al. Cyclo‐oxygenase‐1 and −2 contribution to endothelial dysfunction in ageing , 2000, British journal of pharmacology.
[309] B. Robinson,et al. Mitochondria, oxygen free radicals, disease and ageing. , 2000, Trends in biochemical sciences.
[310] G. Semenza,et al. Age-dependent Defect in Vascular Endothelial Growth Factor Expression Is Associated with Reduced Hypoxia-inducible Factor 1 Activity* , 2000, The Journal of Biological Chemistry.
[311] John P. Cooke. Does ADMA cause endothelial dysfunction? , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[312] J. Loscalzo. What we know and don't know about L-arginine and NO. , 2000, Circulation.
[313] A. Majumdar,et al. Induction of transcriptional activity of AP-1 and NF-kappaB in the gastric mucosa during aging. , 2000, American journal of physiology. Gastrointestinal and liver physiology.
[314] A. Levy,et al. The function of hypoxia‐inducible factor 1 (HIF‐1) is impaired in senescent mice , 1999, FEBS letters.
[315] G. Gabbiani,et al. Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation. , 1999, Arteriosclerosis, thrombosis, and vascular biology.
[316] Pier Paolo Pandolfi,et al. The p66shc adaptor protein controls oxidative stress response and life span in mammals , 1999, Nature.
[317] S. Milstien,et al. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. , 1999, Biochemical and biophysical research communications.
[318] P. Tsao,et al. Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. , 1999, Circulation.
[319] A. Hofman,et al. Dietary antioxidants and risk of myocardial infarction in the elderly: the Rotterdam Study. , 1999, The American journal of clinical nutrition.
[320] C. Caramelo,et al. Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats. , 1998, Circulation research.
[321] M. Carrier,et al. Interaction between superoxide anion and nitric oxide in the regulation of vascular endothelial function , 1998, British journal of pharmacology.
[322] G. Hansson,et al. Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells. , 1998, Circulation research.
[323] A. Takeshita,et al. Importance of endothelium-derived hyperpolarizing factor in human arteries. , 1997, The Journal of clinical investigation.
[324] S. Nadaud,et al. Circulating and cellular markers of endothelial dysfunction with aging in rats. , 1997, American journal of physiology. Heart and circulatory physiology.
[325] A. Salminen,et al. Age-related changes in the regulation of transcription factor NF-κB in rat brain , 1997, Neuroscience Letters.
[326] L. Ghiadoni,et al. Hypertension causes premature aging of endothelial function in humans. , 1997, Hypertension.
[327] T. Oury,et al. Extracellular superoxide dismutase: a regulator of nitric oxide bioavailability. , 1996, Laboratory investigation; a journal of technical methods and pathology.
[328] V. O’Donnell,et al. Expression of phagocyte NADPH oxidase components in human endothelial cells. , 1996, The American journal of physiology.
[329] A. Salminen,et al. Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B. , 1996, The Biochemical journal.
[330] T. Harris,et al. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly. , 1996, The American journal of clinical nutrition.
[331] J. Umans,et al. Effect of pregnancy on mechanisms of relaxation in human omental microvessels. , 1996, Hypertension.
[332] F. Kelly,et al. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) , 1996, The Lancet.
[333] G A Colditz,et al. A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. , 1995, Annals of epidemiology.
[334] A. A. Taylor,et al. Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries. , 1993, The Journal of clinical investigation.
[335] B Chance,et al. Hydroperoxide metabolism in mammalian organs. , 1979, Physiological reviews.
[336] H. Selye. The Stress of Life , 1958 .
[337] D. Harman. Aging: a theory based on free radical and radiation chemistry. , 1956, Journal of gerontology.
[338] J. Carvalho-de-Souza,et al. BK Channels in Cardiovascular Diseases and Aging. , 2013, Aging and disease.
[339] F. Inserra,et al. Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria? , 2011, Cardiovascular research.
[340] J. Erusalimsky. Vascular endothelial senescence: from mechanisms to pathophysiology. , 2009, Journal of applied physiology.
[341] P. Calder,et al. Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations. , 2008, Atherosclerosis.
[342] E. Schiffrin. Oxidative stress, nitric oxide synthase, and superoxide dismutase: a matter of imbalance underlies endothelial dysfunction in the human coronary circulation. , 2008, Hypertension.
[343] C. Baufreton,et al. Alteration in flow (shear stress)-induced remodelling in rat resistance arteries with aging: improvement by a treatment with hydralazine. , 2008, Cardiovascular research.
[344] L. Liaudet,et al. Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.
[345] D. Leibfritz,et al. Free radicals and antioxidants in normal physiological functions and human disease. , 2007, The international journal of biochemistry & cell biology.
[346] D. Seals,et al. Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression. , 2007, Journal of applied physiology.
[347] I. West,et al. The direct physiological effects of mitoK(ATP) opening on heart mitochondria. , 2006, American journal of physiology. Heart and circulatory physiology.
[348] S. Rohrbach,et al. Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart , 2005, Biogerontology.
[349] S. Bandinelli,et al. CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC only. TRIALS The , 2004 .
[350] R. Andriantsitohaina,et al. Age-Related Endothelial Dysfunction , 2003 .
[351] S. Tanguy,et al. Aging exacerbates hydrogen peroxide-induced alteration of vascular reactivity in rats. , 2000, Antioxidants & redox signaling.
[352] S. Bode-Böger,et al. Asymmetric Dimethylarginine, Derangements of the Endothelial Nitric Oxide Synthase Pathway, and Cardiovascular Diseases , 2000, Seminars in thrombosis and hemostasis.
[353] E. Lakatta,et al. Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats. , 1999, Hypertension.
[354] Published online in Wiley InterScience (www.interscience.wiley.com) DOI: 10.1002/path.2101 Review Article , 2022 .