Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence.
暂无分享,去创建一个
Izumi Horikawa | Antti Kokko | Päivi Laiho | L. Aaltonen | C. Harris | P. Laiho | I. Horikawa | Qin Yang | A. Kokko | Lauri A Aaltonen | Ran Zhang | Curtis C Harris | Qin Yang | Y. Afshar | Kaori Fujita | Ran Zhang | Yalda Afshar | K. Fujita | Antti Kokko
[1] C. Harris,et al. POT1 and TRF2 Cooperate To Maintain Telomeric Integrity , 2005, Molecular and Cellular Biology.
[2] R. DePinho,et al. Connecting chromosomes, crisis, and cancer. , 2002, Science.
[3] T. Cech,et al. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[4] T. Cech,et al. Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection , 2004, Nature Structural &Molecular Biology.
[5] T. Veldman,et al. Loss of hPot1 Function Leads to Telomere Instability and a cut-like Phenotype , 2004, Current Biology.
[6] J. Shay,et al. POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end , 2005, The EMBO journal.
[7] Jun Qin,et al. PTOP interacts with POT1 and regulates its localization to telomeres , 2004, Nature Cell Biology.
[8] T. Lange,et al. Recent Expansion of the Telomeric Complex in Rodents: Two Distinct POT1 Proteins Protect Mouse Telomeres , 2006, Cell.
[9] L. Aaltonen,et al. Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. , 1998, The New England journal of medicine.
[10] Robert A. Weinberg,et al. Comparative Biology of Mouse versus Human Cells: Modelling Human Cancer in Mice O P I N I O N , 2022 .
[11] W. Hahn,et al. Erosion of the telomeric single-strand overhang at replicative senescence , 2003, Nature Genetics.
[12] T. Lange,et al. Shelterin: the protein complex that shapes and safeguards human telomeres , 2005 .
[13] K. Kinzler,et al. Genetic instability in colorectal cancers , 1997, Nature.
[14] J. Deng,et al. Pot1 Deficiency Initiates DNA Damage Checkpoint Activation and Aberrant Homologous Recombination at Telomeres , 2006, Cell.
[15] T. Cech,et al. POT1 Stimulates RecQ Helicases WRN and BLM to Unwind Telomeric DNA Substrates* , 2005, Journal of Biological Chemistry.
[16] J. Griffith,et al. Mammalian Telomeres End in a Large Duplex Loop , 1999, Cell.
[17] A. Smogorzewska,et al. Different telomere damage signaling pathways in human and mouse cells , 2002, The EMBO journal.
[18] K. Shin‐ya,et al. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells , 2006, Oncogene.
[19] J. Barrett,et al. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks , 2004, Nature Cell Biology.
[20] T. Cech,et al. The POT1–TPP1 telomere complex is a telomerase processivity factor , 2007, Nature.
[21] B. Chait,et al. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. , 2004, Genes & development.
[22] A. Multani,et al. POT1b protects telomeres from end‐to‐end chromosomal fusions and aberrant homologous recombination , 2006, The EMBO journal.
[23] P. Baumann,et al. Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans , 2001, Science.
[24] L. Aaltonen,et al. Population-based molecular detection of hereditary nonpolyposis colorectal cancer. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] Dan Liu,et al. TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase , 2007, Nature.
[26] Izumi Horikawa,et al. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. , 2005, Molecular biology of the cell.
[27] Bas van Steensel,et al. TRF2 Protects Human Telomeres from End-to-End Fusions , 1998, Cell.
[28] B. van Steensel,et al. Control of Human Telomere Length by TRF1 and TRF2 , 2000, Molecular and Cellular Biology.
[29] J. Mergny,et al. Human replication protein A unfolds telomeric G-quadruplexes , 2006, Nucleic acids research.
[30] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[31] R. Bernards,et al. A System for Stable Expression of Short Interfering RNAs in Mammalian Cells , 2002, Science.
[32] P. Baumann,et al. Human POT1 Facilitates Telomere Elongation by Telomerase , 2003, Current Biology.
[33] D. Feldser,et al. Telomere dysfunction and the initiation of genome instability , 2003, Nature Reviews Cancer.
[34] T. Lange,et al. Identification of Human Rap1 Implications for Telomere Evolution , 2000, Cell.
[35] T. Lange,et al. Significant Role for p16INK4a in p53-Independent Telomere-Directed Senescence , 2004, Current Biology.
[36] P. Baumann,et al. Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative Splicing , 2002, Molecular and Cellular Biology.
[37] E. Appella,et al. Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression. , 2002, Molecular biology of the cell.
[38] M. Oshimura,et al. Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis. , 1997, Cancer genetics and cytogenetics.
[39] E. Blackburn,et al. Telomeres and telomerase: their mechanisms of action and the effects of altering their functions , 2005, FEBS letters.
[40] Sajeev P. Cherian,et al. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. , 1994, Cancer research.
[41] T. Lange,et al. POT1 as a terminal transducer of TRF1 telomere length control , 2003, Nature.
[42] T. Kunkel,et al. Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. , 1997, Cancer research.
[43] S. Dupuis,et al. Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase , 1998, Nature Genetics.
[44] J. Barrett,et al. Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells. , 2004, Blood.
[45] E. Rogakou,et al. Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo , 1999, The Journal of cell biology.
[46] C. Price,et al. Vertebrate POT1 Restricts G-Overhang Length and Prevents Activation of a Telomeric DNA Damage Checkpoint but Is Dispensable for Overhang Protection , 2006, Molecular and Cellular Biology.
[47] M. Meyn,et al. Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage , 2005, Nature Genetics.
[48] T. Cech,et al. Switching Human Telomerase On and Off with hPOT1 Protein in Vitro* , 2005, Journal of Biological Chemistry.