Berberine inhibits the proliferation and migration of breast cancer ZR-75-30 cells by targeting Ephrin-B2.

[1]  Lijuan Fu,et al.  Berberine enhances the anti‑tumor activity of tamoxifen in drug‑sensitive MCF‑7 and drug‑resistant MCF‑7/TAM cells. , 2016, Molecular medicine reports.

[2]  Chunyan Wang,et al.  The Therapeutic Effect of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-Analysis , 2016, Evidence-based complementary and alternative medicine : eCAM.

[3]  Jin Xiang,et al.  Tumor suppressor berberine binds VASP to inhibit cell migration in basal-like breast cancer , 2016, Oncotarget.

[4]  C. Porcher,et al.  EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta , 2016, Scientific Reports.

[5]  Meixiang Xiang,et al.  EphrinB2/EphB4 pathway in postnatal angiogenesis: a potential therapeutic target for ischemic cardiovascular disease , 2016, Angiogenesis.

[6]  M. Yuen,et al.  Berberine and Coptidis Rhizoma as potential anticancer agents: Recent updates and future perspectives. , 2015, Journal of ethnopharmacology.

[7]  H. Gali-Muhtasib,et al.  Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis , 2015, Apoptosis.

[8]  J. Clements,et al.  Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: implications for xenograft models of human prostate cancer. , 2015, Experimental cell research.

[9]  P. Ismail,et al.  Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. , 2014, European journal of pharmacology.

[10]  A. Scovassi,et al.  Berberine, an Epiphany Against Cancer , 2014, Molecules.

[11]  Dong-fang Wu,et al.  Berberine hydrochloride impact on physiological processes and modulation of twist levels in nasopharyngeal carcinoma CNE-1 cells. , 2014, Asian Pacific journal of cancer prevention : APJCP.

[12]  D. Megías,et al.  Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth. , 2012, Blood.

[13]  M. Henkemeyer,et al.  Ephrin-B reverse signaling controls septation events at the embryonic midline through separate tyrosine phosphorylation-independent signaling avenues. , 2011, Developmental biology.

[14]  A. Acker-Palmer,et al.  Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration , 2011, Nature.

[15]  J. Frisén,et al.  Ephrins and Eph receptors in stem cells and cancer. , 2010, Current opinion in cell biology.

[16]  A. Eichmann,et al.  VEGF and ephrin-B2: a bloody duo , 2010, Nature Medicine.

[17]  Langchong He,et al.  Investigation of calcium antagonist–L-type calcium channel interactions by a vascular smooth muscle cell membrane chromatography method , 2010, Analytical and bioanalytical chemistry.

[18]  A. Barberis,et al.  Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis , 2010, Nature.

[19]  Till Acker,et al.  Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis , 2010, Nature.

[20]  N. Seeram,et al.  Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. , 2010, Cancer research.

[21]  D. Wilkinson,et al.  Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly. , 2004, Developmental cell.

[22]  G. Yancopoulos,et al.  EphB ligand, ephrinB2, suppresses the VEGF‐ and angiopoietin‐1‐induced Ras/mitogen‐activated protein kinase pathway in venous endothelial cells , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.