Chromone and chromanone derivatives as strand transfer inhibitors of HIV-1 integrase

[1]  Myriam Witvrouw,et al.  Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors. , 2005, Journal of medicinal chemistry.

[2]  S. Y. Kim,et al.  Macrocyclic diacylglycerol-bis-lactones as conformationally constrained analogues of diacylglycerol-lactones. Interactions with protein kinase C. , 2004, Journal of medicinal chemistry.

[3]  Yun Tang,et al.  Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors. , 2002, Journal of medicinal chemistry.

[4]  Amy S. Espeseth,et al.  Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[5]  Y. Pommier,et al.  Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase. , 2001, Bioorganic & medicinal chemistry.

[6]  K. Mori,et al.  Synthesis and Absolute Configuration of (−)-Neuchromenin, a Neurotrophic Metabolite ofEupenicillium javanicum var.meloforme, and Its Enantiomer , 2001 .

[7]  H. M. Langford,et al.  4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells. , 2000, Journal of medicinal chemistry.

[8]  J A Grobler,et al.  Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. , 2000, Science.

[9]  A. Engelman,et al.  Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication , 1995, Journal of virology.

[10]  William P. May,et al.  Benzenepropanoic acids containing chromanone or naphthalenone moieties are potent and orally active leukotriene B4 antagonists , 1994 .

[11]  J. Chermann,et al.  Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). , 1983, Science.

[12]  T. B. Lee,et al.  Antagonists of slow reacting substance of anaphylaxis. Synthesis of a series of chromone-2-carboxylic acids. , 1977, Journal of medicinal chemistry.

[13]  Shin Cha-Gyun,et al.  Synthesis and Hiv-1 Integrase Inhibitory Activities of 4-Hydroxy-5-azacoumarin 3-Carboxamides , 2007 .

[14]  Y. Pommier,et al.  Inhibitors of human immunodeficiency virus integrase. , 1999, Advances in virus research.

[15]  P. Brown,et al.  Integration of retroviral DNA. , 1990, Current topics in microbiology and immunology.

[16]  B. Föhlisch.  Notiz über eine neue Chromon‐Synthese , 1971 .

[17]  B. B. Millward.  5. A new chromone synthesis , 1960 .