Systemic milieu and age-related deterioration

[1]  K. Friedland,et al.  Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer’s Disease , 2018, Aging and disease.

[2]  B. Fu,et al.  Youthful systemic milieu alleviates renal ischemia-reperfusion injury in elderly mice. , 2018, Kidney international.

[3]  C. Paúl,et al.  Cardiovascular Risk Factors Are Correlated with Low Cognitive Function among Older Adults Across Europe Based on The SHARE Database , 2018, Aging and disease.

[4]  S. Villeda,et al.  The systemic environment: at the interface of aging and adult neurogenesis , 2017, Cell and Tissue Research.

[5]  K. Jin,et al.  Aging Systemic Milieu Impairs Outcome after Ischemic Stroke in Rats , 2017, Aging and disease.

[6]  Izumi V. Hinkson,et al.  Human umbilical cord plasma proteins revitalize hippocampal function in aged mice , 2017, Nature.

[7]  I. Conboy,et al.  A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood , 2016, Nature Communications.

[8]  A. R. Folgueras,et al.  GDF11 administration does not extend lifespan in a mouse model of premature aging , 2016, Oncotarget.

[9]  A. Butt,et al.  Decreased Regenerative Capacity of Oligodendrocyte Progenitor Cells (NG2-Glia) in the Ageing Brain: A Vicious Cycle of Synaptic Dysfunction, Myelin Loss and Neuronal Disruption? , 2016, Current Alzheimer research.

[10]  A. Billin,et al.  Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells , 2016, Aging cell.

[11]  S. Houser,et al.  GDF11 does not rescue aging-related pathological hypertrophy. , 2015, Circulation research.

[12]  I. Conboy,et al.  Systemic Problems: A perspective on stem cell aging and rejuvenation , 2015, Aging.

[13]  I. Clay,et al.  GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration. , 2015, Cell metabolism.

[14]  M. Rudnicki,et al.  GDF11 and the Mythical Fountain of Youth. , 2015, Cell metabolism.

[15]  Derrick J. Rossi,et al.  Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease. , 2015, Cell stem cell.

[16]  Magda Tsolaki,et al.  Plasma proteins predict conversion to dementia from prodromal disease , 2014, Alzheimer's & Dementia.

[17]  Brianne A. Kent,et al.  Adult hippocampal neurogenesis and its role in cognition. , 2014, Wiley interdisciplinary reviews. Cognitive science.

[18]  S. Gabriel,et al.  Alzheimery's disease pathology is associated with early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci , 2014, Nature neuroscience.

[19]  Richard T. Lee,et al.  Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors , 2014, Science.

[20]  Richard T. Lee,et al.  Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle , 2014, Science.

[21]  Danielle A. Simmons,et al.  Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice , 2014, Nature Medicine.

[22]  T. Wyss-Coray,et al.  A revival of parabiosis in biomedical research. , 2014, Swiss medical weekly.

[23]  R. P. Kraig,et al.  Youth and environmental enrichment generate serum exosomes containing miR‐219 that promote CNS myelination , 2014, Glia.

[24]  C. Harada,et al.  Normal cognitive aging. , 2013, Clinics in geriatric medicine.

[25]  I. Weissman,et al.  Parabiosis in mice: a detailed protocol. , 2013, Journal of visualized experiments : JoVE.

[26]  Yun‐Sil Lee,et al.  Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2 , 2013, Proceedings of the National Academy of Sciences.

[27]  A. Mcpherron.  Through thick and thin: a circulating growth factor inhibits age-related cardiac hypertrophy. , 2013, Circulation research.

[28]  T. Rando,et al.  Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity , 2013, Aging cell.

[29]  A. Pasipoularides.  Historical Perspective: Harvey's epoch-making discovery of the Circulation, its historical antecedents, and some initial consequences on medical practice. , 2013, Journal of applied physiology.

[30]  Richard T. Lee,et al.  Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy , 2013, Cell.

[31]  T. Wyss-Coray,et al.  The circulatory systemic environment as a modulator of neurogenesis and brain aging. , 2013, Autoimmunity reviews.

[32]  P. Learoyd,et al.  The history of blood transfusion prior to the 20th century – Part 1 , 2012, Transfusion medicine.

[33]  T. Rando,et al.  Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches , 2012, Cell cycle.

[34]  Manel Esteller,et al.  Hot topics in epigenetic mechanisms of aging: 2011 , 2012, Aging cell.

[35]  R. Franklin,et al.  Rejuvenation of regeneration in the aging central nervous system. , 2012, Cell stem cell.

[36]  J. Kaye,et al.  The aging systemic milieu negatively regulates neurogenesis and cognitive function , 2011, Nature.

[37]  Richard F. Thompson,et al.  Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease , 2010, Proceedings of the National Academy of Sciences.

[38]  A. Hannan,et al.  The neurobiology of brain and cognitive reserve: Mental and physical activity as modulators of brain disorders , 2009, Progress in Neurobiology.

[39]  K. Nave,et al.  The role of CNS glia in preserving axon function , 2009, Current Opinion in Neurobiology.

[40]  G. Kempermann,et al.  Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies , 2009, PloS one.

[41]  A. Brower,et al.  Extensive remyelination of the CNS leads to functional recovery , 2009, Proceedings of the National Academy of Sciences.

[42]  G. Kempermann.  The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for? , 2008, Trends in Neurosciences.

[43]  C. Keller,et al.  Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis , 2007, Science.

[44]  Manel Esteller,et al.  Epigenetics and aging: the targets and the marks. , 2007, Trends in genetics : TIG.

[45]  Lin Xie,et al.  Evidence for stroke-induced neurogenesis in the human brain , 2006, Proceedings of the National Academy of Sciences.

[46]  G. Aurigemma.  Diastolic heart failure--a common and lethal condition by any name. , 2006, The New England journal of medicine.

[47]  I. Weissman,et al.  Rejuvenation of aged progenitor cells by exposure to a young systemic environment , 2005, Nature.

[48]  Gayle M. Smythe,et al.  Notch-Mediated Restoration of Regenerative Potential to Aged Muscle , 2003, Science.

[49]  O. Lindvall,et al.  Neuronal replacement from endogenous precursors in the adult brain after stroke , 2002, Nature Medicine.

[50]  Chao Zhao,et al.  The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation , 2002, The Journal of Neuroscience.

[51]  T. Baskett.  James Blundell: the first transfusion of human blood. , 2002, Resuscitation.

[52]  S. Bennett,et al.  Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis , 2001, Neuroscience.

[53]  K. Ashe.  Learning and memory in transgenic mice modeling Alzheimer's disease. , 2001, Learning & memory.

[54]  M. Matzuk,et al.  Studying TGF-β superfamily signaling by knockouts and knockins , 2001, Molecular and Cellular Endocrinology.

[55]  M. Moskowitz,et al.  FGF-2 regulation of neurogenesis in adult hippocampus after brain injury , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[56]  David A. Greenberg,et al.  Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[57]  V. Rosen,et al.  Gdf11 is a negative regulator of chondrogenesis and myogenesis in the developing chick limb. , 2001, Developmental biology.

[58]  Daniel A. Lim,et al.  Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain , 1999, Cell.

[59]  D. van der Kooy,et al.  Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics , 1999, The Journal of Neuroscience.

[60]  Jonas Frisén,et al.  Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System , 1999, Cell.

[61]  M. Ramirez-Lassepas,et al.  Stroke and the aging of the brain and the arteries. , 1998, Geriatrics.

[62]  M. Larson,et al.  Assessment of cardiovascular risk factors in the elderly: the Framingham Heart Study. , 1995, Statistics in medicine.

[63]  W. Blakemore,et al.  Failure of remyelination in areas of demyelination produced in the spinal cord of old rats , 1993, Neuropathology and applied neurobiology.

[64]  T. Bliss,et al.  A synaptic model of memory: long-term potentiation in the hippocampus , 1993, Nature.

[65]  P. Lantos,et al.  Distribution and fine structural analysis of undifferentiated cells in the primate subependymal layer. , 1991, Journal of anatomy.

[66]  B. Myhre.  The first recorded blood transfusions: 1656 to 1668 , 1990, Transfusion.

[67]  J. Faulkner,et al.  Muscle transplantation between young and old rats: age of host determines recovery. , 1989, The American journal of physiology.

[68]  L. Jerabek,et al.  TOLERANCE AND THE H‐Y ANTIGEN: REQUIREMENT FOR MALE T CELLS, BUT NOT B CELLS, TO INDUCE TOLERANCE IN NEONATAL FEMALE MICE , 1984, Transplantation.

[69]  R. Elashoff,et al.  Mortality in syngeneic rat parabionts of different chronological age. , 1972, Transactions of the New York Academy of Sciences.

[70]  C. P. Leblond,et al.  NATURE OF DIVIDING NUCLEI IN SKELETAL MUSCLE OF GROWING RATS , 1970, The Journal of cell biology.

[71]  J. Altman,et al.  Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats , 1965, The Journal of comparative neurology.

[72]  J. Altman,et al.  Are New Neurons Formed in the Brains of Adult Mammals? , 1962, Science.

[73]  C. Hall,et al.  Prolongation of survival by parabiosis in strain 129 dystrophic mice. , 1958, The American journal of physiology.

[74]  C M MCCAY,et al.  Experimental prolongation of the life span. , 1956, Research publications - Association for Research in Nervous and Mental Disease.

[75]  J. C. Finerty.  Parabiosis in physiological studies. , 1952, Physiological reviews.

[76]  R. K. Meyer,et al.  An improved method of parabiosis , 1933 .

[77]  C. Waller.  Case of Uterine Hemorrhage, in Which the Operation of Transfusion Was Successfully Performed. , 1825 .

[78]  T. Murphy,et al.  The systemic milieu as a mediator of dietary influence on stem cell function during ageing , 2015, Ageing Research Reviews.

[79]  Guo-Yuan Yang,et al.  MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia. , 2011, Frontiers in bioscience.

[80]  C. Waskow,et al.  Generation of parabiotic mice for the study of DC and DC precursor circulation. , 2010, Methods in molecular biology.

[81]  K. Arnold.  Cerebral blood flow in geriatrics--a review. , 1981, Age and ageing.

[82]  C. Mccay,et al.  Parabiosis between old and young rats. , 1957, Gerontologia.