The lactation curve in cattle: a mathematical model of the mammary gland

SUMMARY A simple model of the mammary gland is described. In this model secretory cells are produced by cell division from undifferentiated cells, and the rate of division is determined by the level of a postulated hormone. The total activity of the milk secreting cells depends on the number of cells, substrate supply (assumed constant), and the amount of milk currently present in the animal. The secretory cells have a finite life, although their death may be expedited by milk remaining in the animal over a longer period of time. The model gives a good description of an experimental lactation curve; it is able to simulate the removal of milk by a suckling calf and machine milking with a variable number of milking periods a day.