Grand Challenges in Discrete Event Logistics Systems

With the experience of dealing with systems as complex as wafer fabrication plants as well as aerospace spare parts logistics networks, I would consider the following four factors as the greatest contemporary challenges for Discrete Event Logistics Systems: (i) Domain-specific characteristics of Discrete Event Logistic Systems, (ii) Cycle time for model generation and model maintenance, (iii) Involvement of humans in operating such systems, (iv) The difficulty of quantifying the value generated by decision-support software for managing and optimising such systems.