Necrosulfonamide - Unexpected effect in the course of a sulfur mustard intoxication.

[1]  G. Dubyak,et al.  Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis , 2018, Science Immunology.

[2]  Junying Yuan,et al.  Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression , 2018, Cell Death & Disease.

[3]  P. Vandenabeele,et al.  Regulated necrosis: disease relevance and therapeutic opportunities , 2016, Nature reviews. Drug discovery.

[4]  L. Zitvogel,et al.  Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy , 2016, Oncoimmunology.

[5]  A. Schmidt,et al.  Protective effects of the thiol compounds GSH and NAC against sulfur mustard toxicity in a human keratinocyte cell line. , 2016, Toxicology letters.

[6]  K. Püschel,et al.  Medical documentation, bioanalytical evidence of an accidental human exposure to sulfur mustard and general therapy recommendations. , 2016, Toxicology letters.

[7]  Yunshan Guo,et al.  Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice. , 2015, American journal of cancer research.

[8]  E. Ratovitski.  Phospho‐ΔNp63α‐responsive microRNAs contribute to the regulation of necroptosis in squamous cell carcinoma upon cisplatin exposure , 2015, FEBS letters.

[9]  A. Eisenthal,et al.  Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury , 2015, Cell Death and Disease.

[10]  M. Bertrand,et al.  Molecular crosstalk between apoptosis, necroptosis, and survival signaling , 2015, Molecular & cellular oncology.

[11]  A. Schmidt,et al.  Development of a co-culture of keratinocytes and immune cells for in vitro investigation of cutaneous sulfur mustard toxicity. , 2014, Chemico-biological interactions.

[12]  Junying Yuan,et al.  Necroptosis in health and diseases. , 2014, Seminars in cell & developmental biology.

[13]  Mackenzie W. Mathis,et al.  Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS , 2014, Neuron.

[14]  A. Schmidt,et al.  Silibinin as a potential therapeutic for sulfur mustard injuries. , 2013, Chemico-biological interactions.

[15]  Xiaodong Wang,et al.  Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase , 2012, Cell.

[16]  L. Bracci,et al.  Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis. , 2011, Cancer research.

[17]  L. Martin,et al.  Necrostatin Decreases Oxidative Damage, Inflammation, and Injury after Neonatal HI , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[18]  K. Kehe,et al.  Rapid simultaneous determination of apoptosis, necrosis, and viability in sulfur mustard exposed HaCaT cell cultures. , 2009, Toxicology letters.

[19]  K. Kehe,et al.  Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering. , 2009, Toxicology.

[20]  A. Bürkle,et al.  Role of poly(ADP-ribose) polymerase in sulfur mustard toxicity. , 2009, Toxicology.

[21]  W. Bloch,et al.  Sulphur mustard induces time- and concentration-dependent regulation of NO-synthesizing enzymes. , 2009, Toxicology letters.

[22]  Tao Wang,et al.  Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α , 2009, Cell.

[23]  Z. Suntres,et al.  Sulfur Mustard Toxicity Following Dermal Exposure: Role of Oxidative Stress, and Antioxidant Therapy , 2007 .

[24]  K. Kehe,et al.  Medical aspects of sulphur mustard poisoning. , 2005, Toxicology.

[25]  J. Foley,et al.  Involvement of tumor necrosis factor-α in sulfur mustard-induced skin lesion; effect of topical iodine , 2005, Archives of Toxicology.

[26]  Alexei Degterev,et al.  Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury , 2005, Nature chemical biology.

[27]  Kriston L. McGary,et al.  An inhibitor of p38 MAP kinase downregulates cytokine release induced by sulfur mustard exposure in human epidermal keratinocytes. , 2004, Toxicology in vitro : an international journal published in association with BIBRA.

[28]  C. Arroyo,et al.  Neutralization effects of interleukin-6 (IL-6) antibodies on sulfur mustard (HD)-induced IL-6 secretion on human epidermal keratinocytes. , 2004, Environmental toxicology and pharmacology.

[29]  J. Schlager,et al.  Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin , 2002, Journal of biochemical and molecular toxicology.

[30]  T. Misteli,et al.  Release of chromatin protein HMGB1 by necrotic cells triggers inflammation , 2002, Nature.

[31]  C. Arroyo,et al.  The Role of Interleukin-6 (IL-6) in Human Sulfur Mustard (HD) Toxicology , 2001, International journal of toxicology.

[32]  C. Santai,et al.  Inflammatory cytokine response in sulfur mustard‐exposed mouse skin † ‡ , 2000, Journal of applied toxicology : JAT.

[33]  D. Lison,et al.  Sulfur mustard upregulates the expression of interleukin-8 in cultured human keratinocytes. , 1999, Toxicology letters.

[34]  C. Simbulan-Rosenthal,et al.  Sulfur mustard induces markers of terminal differentiation and apoptosis in keratinocytes via a Ca2+-calmodulin and caspase-dependent pathway. , 1998, The Journal of investigative dermatology.

[35]  D. Hinshaw,et al.  Sulfur mustard induces apoptosis and necrosis in endothelial cells. , 1996, Toxicology and applied pharmacology.

[36]  N. Fusenig,et al.  Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+. , 1993, Differentiation; research in biological diversity.

[37]  J. Hornung,et al.  Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line , 1988, The Journal of cell biology.

[38]  J. Petrali,et al.  Molecular basis for mustard-induced vesication. , 1985, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[39]  Shigeru Tsuchiya,et al.  Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1) , 1980, International journal of cancer.

[40]  A. Wyllie,et al.  Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.

[41]  A. Gilman,et al.  The initial clinical trial of nitrogen mustard. , 1963, American journal of surgery.

[42]  C. Spurr,et al.  The role of nitrogen mustard therapy in the treatment of lymphomas and leukemias. , 1950, The American journal of medicine.