CLINICAL CORRELATION OF MAGNESIUM LEVELS IN SEVERE PRE ECLAMPSIA AND ECLAMPSIA

To study the normal levels of magnesium in blood in normal pregnant women and clinical signs of various levels of magnesium. To correlate the clinical signs with various magnesium levels in blood with severity of Pre eclampsia and eclampsia.Design:Retrospective study.Setting:In a single hospital. Methodology: The study is to be conducted in Rajah Muthiah Medical Collage and Hospital between the study period October 2012 to October 2014 in department of Obstetrics and Gynecology. Pregnant patients at 20 to 38 weeks of gestational age with single live fetus. The study is prospective comparative evaluation of two groups cpntrol and test group. The study was done in 100 patients of which 50 women are severe pregnancy induced hypertension and eclampsia and other 50 patients are normal women. Serum was analyzed for estimation of Magnesium levels in blood.Statistical analysis - Chi square , and student test t. Results: The result showed that serum magnesium were significantly decreased (P 0.001) in preeclampsia as compared to normal pregnant women as well as healthy controls. Conclusion: This study showed that there is significantly lower level of magnesium in the pre eclamptic pregnant women compared to the normotensive pregnant women. The difference may be due to the variation in the study population and dietary intake. Systemically magnesium lowers blood pressure and alters peripheral vascular resistance. Thus it can be advantageous for pre eclampsia women.