Allogeneic transplantation, Fas signaling, and dysregulation of hepcidin.
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H. Deeg | K. Kowdley | Xiang Li | G. Trobridge | Jean S. Campbell | C. Miao | A. Marcondes | E. Karoopongse | Feng Xu | Kayoung Lee | J. Campbell
[1] A. Buser,et al. Prognostic impact of posttransplantation iron overload after allogeneic stem cell transplantation. , 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[2] Philip D. Zisman,et al. Cellular FLICE-like inhibitory protein deviates myofibroblast fas-induced apoptosis toward proliferation during lung fibrosis. , 2012, American journal of respiratory cell and molecular biology.
[3] A. Safa,et al. c-FLIP, a master anti-apoptotic regulator. , 2012, Experimental oncology.
[4] Liying Wang,et al. Antioxidant c-FLIP Inhibits Fas Ligand-Induced NF-κB Activation in a Phosphatidylinositol 3-Kinase/Akt-Dependent Manner , 2011, The Journal of Immunology.
[5] Thomas B. Sundberg,et al. Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease , 2011, Science Translational Medicine.
[6] H. Deeg,et al. The helix-loop-helix transcription factor TWIST is dysregulated in myelodysplastic syndromes. , 2010, Blood.
[7] A. Marx,et al. A single nucleotide polymorphism determines protein isoform production of the human c-FLIP protein. , 2009, Blood.
[8] H. Deeg,et al. Transplantation of allogeneic T cells alters iron homeostasis in NOD/SCID mice. , 2009, Blood.
[9] H. Deeg,et al. Red blood cell transfusion dependence and outcome after allogeneic peripheral blood stem cell transplantation in patients with de novo myelodysplastic syndrome (MDS). , 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[10] Yigong Shi,et al. FLIP and the death effector domain family , 2008, Oncogene.
[11] M. Wernli,et al. Gli2 upregulates cFlip and renders basal cell carcinoma cells resistant to death ligand-mediated apoptosis , 2008, Oncogene.
[12] H. Deeg,et al. Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2 , 2008, Apoptosis.
[13] Jerry Kaplan,et al. Regulation of iron acquisition and storage: consequences for iron-linked disorders , 2008, Nature Reviews Molecular Cell Biology.
[14] T. Tsuruo,et al. Impairment of the ubiquitin‐proteasome system by cellular FLIP , 2007, Genes to cells : devoted to molecular & cellular mechanisms.
[15] P. Armand,et al. Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation. , 2007, Blood.
[16] G. Ramadori,et al. Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat , 2007, Laboratory Investigation.
[17] Christian Trautwein,et al. STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo. , 2007, Gastroenterology.
[18] P. Krammer,et al. The c-FLIP–NH2 terminus (p22-FLIP) induces NF-κB activation , 2006, The Journal of experimental medicine.
[19] H. Deeg,et al. The clinical spectrum of acute graft-versus-host disease. , 2006, Seminars in hematology.
[20] A. Donovan,et al. Comparative studies of duodenal and macrophage ferroportin proteins. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[21] H. Deeg,et al. Protection of human and murine hepatocytes against Fas-induced death by transferrin and iron , 2006, Apoptosis.
[22] M. Peter,et al. A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes. , 2005, Carcinogenesis.
[23] E. Hurt,et al. The role of IL-6 and STAT3 in inflammation and cancer. , 2005, European journal of cancer.
[24] J. Tschopp,et al. Cellular FLIP (Long Form) Regulates CD8+ T Cell Activation through Caspase-8-Dependent NF-κB Activation1 , 2005, The Journal of Immunology.
[25] M. Manns,et al. The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. , 2005, The Journal of clinical investigation.
[26] M. Peter. The flip side of FLIP. , 2004, The Biochemical journal.
[27] E. Holler,et al. Induction of heme oxygenase-1 before conditioning results in improved survival and reduced graft-versus-host disease after experimental allogeneic bone marrow transplantation. , 2004, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[28] Elizabeta Nemeth,et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. , 2004, The Journal of clinical investigation.
[29] J. Tschopp,et al. N-Terminal Fragment of c-FLIP(L) Processed by Caspase 8 Specifically Interacts with TRAF2 and Induces Activation of the NF-κB Signaling Pathway , 2004, Molecular and Cellular Biology.
[30] H. Deeg,et al. Prevention of Fas-mediated hepatic failure by transferrin , 2004, Laboratory Investigation.
[31] Wan-Ni Yu,et al. Phosphatidylinositide 3-Kinase Priming Couples c-FLIP to T Cell Activation* , 2004, Journal of Biological Chemistry.
[32] R. Taub. Hepatoprotection via the IL-6/Stat3 pathway. , 2003, The Journal of clinical investigation.
[33] C. Miao,et al. High-level factor VIII gene expression in vivo achieved by nonviral liver-specific gene therapy vectors. , 2003, Human gene therapy.
[34] K. Shiraki,et al. Cellular FLICE/Caspase-8–Inhibitory Protein as a Principal Regulator of Cell Death and Survival in Human Hepatocellular Carcinoma , 2003, Laboratory Investigation.
[35] J. Tschopp,et al. The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex* , 2002, The Journal of Biological Chemistry.
[36] Masaharu Akiyama,et al. Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications , 2002, Oncogene.
[37] N. Mounier,et al. CD95 engagement induces disseminated endothelial cell apoptosis in vivo: immunopathologic implications. , 2002, Blood.
[38] J. Maher,et al. Anti-Fas Induces Hepatic Chemokines and Promotes Inflammation by an NF-κB-independent, Caspase-3-dependent Pathway* , 2001, The Journal of Biological Chemistry.
[39] Margot Thome,et al. Regulation of lymphocyte proliferation and death by flip , 2001, Nature Reviews Immunology.
[40] G. Ciliberto,et al. Interleukin-6 Protects against Fas-mediated Death by Establishing a Critical Level of Anti-apoptotic Hepatic Proteins FLIP, Bcl-2, and Bcl-xL* , 2001, The Journal of Biological Chemistry.
[41] D. Brenner,et al. NF-κB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-α– and Fas-mediated apoptosis , 2001 .
[42] F. Martinon,et al. The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways , 2000, Current Biology.
[43] K. Matsushima,et al. Active participation of CCR5(+)CD8(+) T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease. , 1999, The Journal of clinical investigation.
[44] S. Nagata,et al. Therapeutic effect of an anti-Fas ligand mAb on lethal graft-versus-host disease. , 1999, International immunology.
[45] Margot Thome,et al. Inhibition of death receptor signals by cellular FLIP , 1997, Nature.
[46] I. Stamenkovic,et al. The CD95 (APO-1/Fas) Receptor Activates NF-B Independently of Its Cytotoxic Function (*) , 1996, The Journal of Biological Chemistry.
[47] S. Weitzman,et al. Sequential changes in serum iron and ferritin in patients undergoing high-dose chemotherapy and radiation with autologous bone marrow transplantation: possible implications for treatment related toxicity. , 1995, Free radical biology & medicine.
[48] T. Libermann,et al. Activation of interleukin-6 gene expression through the NF-kappa B transcription factor , 1990, Molecular and cellular biology.