The Regulation of Glucose Metabolism by HIF-1 Mediates a Neuroprotective Response to Amyloid Beta Peptide

[1]  Subramanian Rajagopalan,et al.  Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo A Novel Therapy for Parkinson's Disease , 2003, Neuron.

[2]  D. Mottet,et al.  Regulation of gene expression by oxygen: NF-kappaB and HIF-1, two extremes. , 2002, Free radical biology & medicine.

[3]  M. Bernaudin,et al.  Brain Genomic Response following Hypoxia and Re-oxygenation in the Neonatal Rat , 2002, The Journal of Biological Chemistry.

[4]  D. Mottet,et al.  Is HIF-1α a pro- or an anti-apoptotic protein? ☆ , 2002 .

[5]  G. Fink,et al.  Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration , 2002, Nature.

[6]  G. Gibson.  Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease. , 2002, Free radical biology & medicine.

[7]  O. Boulat,et al.  Alteration of amino acid metabolism in neuronal aggregate cultures exposed to hypoglycaemic conditions , 2002, Journal of neurochemistry.

[8]  D. Schubert,et al.  Specificity of resistance to oxidative stress , 2002, Journal of neurochemistry.

[9]  R. Strohman,et al.  Maneuvering in the Complex Path from Genotype to Phenotype , 2002, Science.

[10]  R. Wenger,et al.  Heat Induction of the Unphosphorylated Form of Hypoxia-inducible Factor-1α Is Dependent on Heat Shock Protein-90 Activity* , 2002, The Journal of Biological Chemistry.

[11]  A. Freeman,et al.  Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine , 2001, Brain Research.

[12]  H. Pinedo,et al.  Induction of Vascular Endothelial Growth Factor Expression and Hypoxia-inducible Factor 1α Protein by the Oxidative Stressor Arsenite* , 2001, The Journal of Biological Chemistry.

[13]  J. Blass.  Brain metabolism and brain disease: Is metabolic deficiency the proximate cause of Alzheimer dementia? , 2001, Journal of neuroscience research.

[14]  G. Cole,et al.  The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse , 2001, The Journal of Neuroscience.

[15]  C. Masters,et al.  Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice , 2001, Neuron.

[16]  M. Beal,et al.  Metal Chelator Decreases Alzheimer β-Amyloid Plaques , 2001, Neuron.

[17]  C. Finch,et al.  Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum? , 2001, Trends in Neurosciences.

[18]  P. Maher,et al.  Regulation of Antioxidant Metabolism by Translation Initiation Factor 2α , 2001, The Journal of cell biology.

[19]  R. Terry.  Cell death or synaptic loss in Alzheimer disease. , 2000, Journal of neuropathology and experimental neurology.

[20]  T. Pagano,et al.  Insulin receptors and insulin action in the brain: review and clinical implications , 2000, Neuroscience & Biobehavioral Reviews.

[21]  J. Yu,et al.  A method for determination of pyridine nucleotides using a single extract. , 2000, Analytical biochemistry.

[22]  J. Schwartz,et al.  Two splice variants of the hypoxia‐inducible factor HIF‐1α as potential dimerization partners of ARNT2 in neurons , 2000, The European journal of neuroscience.

[23]  E. Dufour,et al.  A causal link between respiration and senescence in Podospora anserina. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[24]  A Hofman,et al.  Diabetes mellitus and the risk of dementia , 1999, Neurology.

[25]  R. L. Russell,et al.  Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease. , 1999, Archives of biochemistry and biophysics.

[26]  J. Caro,et al.  Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins. , 1999, Biochemical and biophysical research communications.

[27]  W. Kaelin.  Cancer: Many vessels, faulty gene , 1999, Nature.

[28]  C. Wykoff,et al.  The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis , 1999, Nature.

[29]  D. Dwyer,et al.  Antipsychotic drugs affect glucose uptake and the expression of glucose transporters in PC12 cells , 1999, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[30]  S. Filosa,et al.  Enhanced Glutathione Levels and Oxidoresistance Mediated by Increased Glucose-6-phosphate Dehydrogenase Expression* , 1999, The Journal of Biological Chemistry.

[31]  P. Maher,et al.  A Role for 12-lipoxygenase in Nerve Cell Death Caused by Glutathione Depletion , 1997, Neuron.

[32]  K. Brand.  Aerobic Glycolysis by Proliferating Cells: Protection against Oxidative Stress at the Expense of Energy Yield , 1997, Journal of bioenergetics and biomembranes.

[33]  D. Peterson,et al.  Mechanism of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction , 1997, Journal of neurochemistry.

[34]  A. Parpura-Gill,et al.  The inhibitory effects of β-amyloid on glutamate and glucose uptakes by cultured astrocytes , 1997, Brain Research.

[35]  Joseph S. Beckman,et al.  Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease , 1997, The Journal of Neuroscience.

[36]  S. Masuda,et al.  [Regulation of gene expression by oxygen]. , 1996, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

[37]  Y. Sheline,et al.  Memory improvement following induced hyperinsulinemia in alzheimer's disease , 1996, Neurobiology of Aging.

[38]  C. Behl,et al.  Increased antioxidant enzyme activity in amyloid beta protein-resistant cells , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[39]  D. Schubert,et al.  The role of iron in beta amyloid toxicity. , 1995, Biochemical and biophysical research communications.

[40]  G. Semenza,et al.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[41]  C. Behl,et al.  Hydrogen peroxide mediates amyloid β protein toxicity , 1994, Cell.

[42]  P. E. Gold,et al.  Glucose enhancement of memory in patients with probable senile dementia of the Alzheimer's type , 1993, Neurobiology of Aging.

[43]  C. Behl,et al.  Heat shock partially protects rat pheochromocytoma PC12 cells from amyloid β peptide toxicity , 1993, Neuroscience Letters.

[44]  K. Herholz,et al.  Differences of regional cerebral glucose metabolism between presenile and senile dementia of Alzheimer type , 1992, Neurobiology of Aging.

[45]  W. Lukiw,et al.  Would decreased aluminum ingestion reduce the incidence of Alzheimer's disease? , 1991, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[46]  R. Henneberry,et al.  Expression of two glucose transporters, GLUT1 and GLUT3, in cultured cerebellar neurons: Evidence for neuron-specific expression of GLUT3 , 1991, Molecular and Cellular Neuroscience.

[47]  D. Kirschner,et al.  Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. , 1990, Science.

[48]  L. Kedes,et al.  Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts , 1990, Journal of cellular physiology.

[49]  D. Hinshaw,et al.  Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide. , 1988, The Journal of biological chemistry.

[50]  D. Neary,et al.  Mitochondrial function in brain tissue in primary degenerative dementia , 1987, Brain Research.

[51]  H. Wiśniewski,et al.  Alzheimer's disease in Down's syndrome , 1985, Neurology.

[52]  C. Grady,et al.  Down's syndrome in adults: brain metabolism. , 1983, Science.

[53]  D. Neary,et al.  Metabolic Processes in Alzheimer's Disease: Adenine Nucleotide Content and Production of 14CO2 from [U‐14C]Glucose In Vitro in Human Neocortex , 1983, Journal of neurochemistry.

[54]  N. Sims,et al.  [14C]acetylcholine synthesis and [14C]carbon dioxide production from [U-14C]glucose by tissue prisms from human neocortex. , 1981, The Biochemical journal.

[55]  W. Meier-Ruge,et al.  ACCELERATED AGEING OR SELECTIVE NEURONAL LOSS AS AN IMPORTANT CAUSE OF DEMENTIA? , 1979, The Lancet.

[56]  P. J. Randle,et al.  The pentose cycle and insulin release in mouse pancreatic islets. , 1972, The Biochemical journal.

[57]  D. Owens,et al.  Alzheimer's disease in Down's syndrome. , 1971, American journal of mental deficiency.

[58]  B. Hiles.  HYPERGLYCEMIA AND GLYCOSURIA FOLLOWING CHLORPROMAZINE THERAPY , 1956 .

[59]  D. Davies,et al.  Immunolabelling of hippocampal microvessel glucose transporter protein is reduced in Alzheimer's disease , 2004, Virchows Archiv.

[60]  G. Semenza,et al.  Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. , 1999, Annual review of cell and developmental biology.

[61]  A. M. Palmer,et al.  The activity of the pentose phosphate pathway is increased in response to oxidative stress in Alzheimer's disease , 1999, Journal of Neural Transmission.

[62]  E. Masliah,et al.  Structural basis of the cognitive alterations in Alzheimer disease. , 1994 .

[63]  M. Brostrom,et al.  Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells. , 1993, The Biochemical journal.

[64]  W. Lukiw,et al.  WOULD DECREASED ALUMINIUM INGESTION REDUCED THE INCIDENCE OF ALZHEIMER'S DISEASE ? , 1991 .

[65]  V. Esmann.  Regulatory mechanisms of carbohydrate metabolism , 1978 .

[66]  Lillian A. Decker.  Worthington enzyme manual : enzymes, enzyme reagents, related biochemicals , 1977 .

[67]  E. Thonnard-Neumann.  Phenothiazines and diabetes in hospitalized women. , 1968, The American journal of psychiatry.

[68]  G. Arneson.  PHENOTHIAZINE DERIVATIVES AND GLUCOSE METABOLISM. , 1964, Journal of neuropsychiatry.