Recessive cancer genes engage in negative genetic interactions with their functional paralogs.

[1]  Heming Xiao,et al.  Theoretical studies of energetic nitrogen-rich ionic salts composed of substituted 5-nitroiminotetrazolate anions and various cations , 2013, Journal of Molecular Modeling.

[2]  K. Kinzler,et al.  Cancer Genome Landscapes , 2013, Science.

[3]  D. Reisman,et al.  Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity. , 2012, Experimental cell research.

[4]  V. Godfrey,et al.  Functional Redundancy of SWI/SNF Catalytic Subunits in Maintaining Vascular Endothelial Cells in the Adult Heart , 2012, Circulation research.

[5]  Irmtraud M. Meyer,et al.  The clonal and mutational evolution spectrum of primary triple-negative breast cancers , 2012, Nature.

[6]  C. Niessen,et al.  Classical and desmosomal cadherins at a glance , 2012, Journal of Cell Science.

[7]  D. Morris,et al.  Personalized medicine in metastatic non-small-cell lung cancer: promising targets and current clinical trials. , 2012, Current oncology.

[8]  J. Kohoutek,et al.  Cyclin K goes with Cdk12 and Cdk13 , 2012, Cell Division.

[9]  H. Dombret,et al.  Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association , 2011, Leukemia.

[10]  Peer Bork,et al.  SMART 7: recent updates to the protein domain annotation resource , 2011, Nucleic Acids Res..

[11]  André F. Vieira,et al.  P-cadherin role in normal breast development and cancer. , 2011, The International journal of developmental biology.

[12]  Vladimir Valera Romero,et al.  The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels. , 2011, Cancer cell.

[13]  Toshihiro Sakurai,et al.  Regulation of trophoblast-specific factors by GATA2 and GATA3 in bovine trophoblast CT-1 cells. , 2011, The Journal of reproduction and development.

[14]  A. Di Cristofano,et al.  New routes to old places: PIK3R1 and PIK3R2 join PIK3CA and PTEN as endometrial cancer genes. , 2011, Cancer discovery.

[15]  R. Jaenisch,et al.  De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. , 2011, Genes & development.

[16]  Francesca D. Ciccarelli,et al.  Modification of Gene Duplicability during the Evolution of Protein Interaction Network , 2011, PLoS Comput. Biol..

[17]  D. Pisano,et al.  Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors , 2011, Human mutation.

[18]  Mingming Jia,et al.  COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer , 2010, Nucleic Acids Res..

[19]  Joshua F. McMichael,et al.  DNMT3A mutations in acute myeloid leukemia. , 2010, The New England journal of medicine.

[20]  Michael Costanzo,et al.  Genetic interactions reveal the evolutionary trajectories of duplicate genes , 2010, Molecular systems biology.

[21]  J. Gil,et al.  Epigenetic regulation of the INK4b-ARF-INK4a locus , 2010, Epigenetics.

[22]  J. Christensen,et al.  PF-03732010: A Fully Human Monoclonal Antibody against P-Cadherin with Antitumor and Antimetastatic Activity , 2010, Clinical Cancer Research.

[23]  Yiyu Dong,et al.  Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer. , 2010, Cancer research.

[24]  Francesca D Ciccarelli,et al.  The (r)evolution of cancer genetics , 2010, BMC Biology.

[25]  A. Chou,et al.  Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC, and SDHD in paraganglioma-pheochromocytoma syndromes. , 2010, Human pathology.

[26]  L. Harries,et al.  Species-Specific Differences in the Expression of the HNF1A, HNF1B and HNF4A Genes , 2009, PloS one.

[27]  Peter A. Jones,et al.  Rethinking how DNA methylation patterns are maintained , 2009, Nature Reviews Genetics.

[28]  Ben S. Wittner,et al.  Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 , 2009, Nature.

[29]  D. Reisman,et al.  The SWI/SNF complex and cancer , 2009, Oncogene.

[30]  P. Hulpiau,et al.  Molecular evolution of the cadherin superfamily. , 2009, The international journal of biochemistry & cell biology.

[31]  Tatiana A. Tatusova,et al.  NCBI Reference Sequences: current status, policy and new initiatives , 2008, Nucleic Acids Res..

[32]  D. Reinberg,et al.  Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. , 2008, Molecular cell.

[33]  Andrea Ciliberto,et al.  Low duplicability and network fragility of cancer genes. , 2008, Trends in genetics : TIG.

[34]  Alan Ashworth,et al.  A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  J. Meléndez-Zajgla,et al.  Participation of Omi Htra2 Serine-Protease Activity in the Apoptosis Induced by Cisplatin on SW480 Colon Cancer Cells , 2008, Journal of chemotherapy.

[36]  C. Disteche,et al.  Sex-Specific Differences in Expression of Histone Demethylases Utx and Uty in Mouse Brain and Neurons , 2008, The Journal of Neuroscience.

[37]  Jason I. Herschkowitz,et al.  Characterization of mammary tumors from Brg1 heterozygous mice , 2008, Oncogene.

[38]  S. Parodi,et al.  PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma. , 2008, International journal of oncology.

[39]  Maite Huarte,et al.  The X-Linked Mental Retardation Gene SMCX/JARID1C Defines a Family of Histone H3 Lysine 4 Demethylases , 2007, Cell.

[40]  A. Tsygankov,et al.  The Cbl family proteins: Ring leaders in regulation of cell signaling , 2006, Journal of cellular physiology.

[41]  David Levens,et al.  FBPs Are Calibrated Molecular Tools To Adjust Gene Expression , 2006, Molecular and Cellular Biology.

[42]  M. Katoh,et al.  CER1 is a common target of WNT and NODAL signaling pathways in human embryonic stem cells. , 2006, International journal of molecular medicine.

[43]  Teresa L. Mastracci,et al.  E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast , 2005, Modern Pathology.

[44]  Thomas Helleday,et al.  Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase , 2005, Nature.

[45]  Alan Ashworth,et al.  Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy , 2005, Nature.

[46]  P. Gain,et al.  Cell and tissue specific expression of human Krüppel-like transcription factors in human ocular surface. , 2004, Molecular vision.

[47]  P. Dallas,et al.  Two related ARID family proteins are alternative subunits of human SWI/SNF complexes. , 2004, The Biochemical journal.

[48]  K. Kinzler,et al.  Cancer genes and the pathways they control , 2004, Nature Medicine.

[49]  T. Hubbard,et al.  A census of human cancer genes , 2004, Nature Reviews Cancer.

[50]  A. Reynolds,et al.  Rational siRNA design for RNA interference , 2004, Nature Biotechnology.

[51]  J. Decaprio,et al.  Molecular cloning and characterization of the von Hippel-Lindau-like protein. , 2004, Molecular cancer research : MCR.

[52]  Weidong Wang,et al.  Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis. , 2003, Cancer research.

[53]  W. J. Kent,et al.  BLAT--the BLAST-like alignment tool. , 2002, Genome research.

[54]  Antonio Giordano,et al.  p300 and CBP: Partners for life and death , 1999, Journal of cellular physiology.