Analysis of exhaled air for early-stage diagnosis of lung cancer: opportunities and challenges

[1]  S. Telser,et al.  Applications of breath gas analysis in medicine , 2004 .

[2]  W. Miekisch,et al.  Breath biomarkers for lung cancer detection and assessment of smoking related effects--confounding variables, influence of normalization and statistical algorithms. , 2010, Clinica chimica acta; international journal of clinical chemistry.

[3]  Fengmin Zhang,et al.  Noninvasive detection of colorectal cancer by analysis of exhaled breath , 2014, Analytical and Bioanalytical Chemistry.

[4]  L. Bianchi,et al.  Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study , 2005, Respiratory research.

[5]  M. Phillips,et al.  Pilot study of a breath test for volatile organic compounds associated with oral malodor: evidence for the role of oxidative stress. , 2005, Oral diseases.

[6]  Nicola Donato,et al.  Real-time monitoring of breath ammonia during haemodialysis: use of ion mobility spectrometry (IMS) and cavity ring-down spectroscopy (CRDS) techniques. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[7]  D. Kotzias,et al.  Decomposition of Terpenes by Ozone during Sampling on Tenax. , 1996, Analytical chemistry.

[8]  A. Davies,et al.  Biomarker validation—room air variation during human breath investigations , 2010 .

[9]  D. Klemp,et al.  Volatile organic compounds in the exhaled breath of young patients with cystic fibrosis , 2006, European Respiratory Journal.

[10]  W. Miekisch,et al.  Multibed needle trap devices for on site sampling and preconcentration of volatile breath biomarkers. , 2009, Analytical chemistry.

[11]  V. Gauci,et al.  Methods in plant foliar volatile organic compounds research1 , 2015, Applications in plant sciences.

[12]  Marc Quirynen,et al.  Differences between alveolar air and mouth air. , 2007, Analytical chemistry.

[13]  S. Hisamichi.  Screening for gastric cancer , 2005, World Journal of Surgery.

[14]  Bogusław Buszewski,et al.  Determination of volatile organic compounds as potential markers of lung cancer by gas chromatography–mass spectrometry versus trained dogs , 2014 .

[15]  P. Zanen,et al.  An off-line breath sampling and analysis method suitable for large screening studies , 2007, Physiological measurement.

[16]  K. Garey,et al.  Collection and analysis of exhaled breath condensate in humans. , 2001, American journal of respiratory and critical care medicine.

[17]  William B. Goggins,et al.  Incidence and mortality of lung cancer: global trends and association with socioeconomic status , 2017, Scientific Reports.

[18]  X. Rosalind Wang,et al.  Human breath-print identification by E-nose, using information-theoretic feature selection prior to classification , 2015 .

[19]  Philipp Sulzer,et al.  From conventional proton-transfer-reaction mass spectrometry (PTR-MS) to universal trace gas analysis , 2012 .

[20]  P. J. Callahan,et al.  Volatile organic compounds as breath biomarkers for active and passive smoking. , 2002, Environmental health perspectives.

[21]  David Smith,et al.  Quantification of acetaldehyde released by lung cancer cells in vitro using selected ion flow tube mass spectrometry. , 2003, Rapid communications in mass spectrometry : RCM.

[22]  K. Unterkofler,et al.  Product ion distributions for the reactions of NO+ with some physiologically significant aldehydes obtained using a SRI-TOF-MS instrument , 2014, International journal of mass spectrometry.

[23]  Josep Sulé-Suso,et al.  Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model. , 2013, The Analyst.

[24]  Anton Amann,et al.  Lung cancer detection by proton transfer reaction mass-spectrometric analysis of human breath gas , 2007 .

[25]  Ildikó Horváth,et al.  Exhaled biomarker pattern is altered in children with obstructive sleep apnoea syndrome. , 2013, International journal of pediatric otorhinolaryngology.

[26]  Lutz Freitag,et al.  Detection of volatile organic compounds (VOCs) in exhaled breath of patients with chronic obstructive pulmonary disease (COPD) by ion mobility spectrometry , 2011 .