Altered peripheral toll‐like receptor responses in the irritable bowel syndrome

Aliment Pharmacol Ther 2011; 33: 1045–1052

[1]  A. Fanning,et al.  Differential Expression of Toll-Like Receptors in Patients With Irritable Bowel Syndrome , 2011, The American Journal of Gastroenterology.

[2]  P. Scully,et al.  Plasma Cytokine Profiles in Females With Irritable Bowel Syndrome and Extra-Intestinal Co-Morbidity , 2010, The American Journal of Gastroenterology.

[3]  S. Akira,et al.  Pattern Recognition Receptors and Inflammation , 2010, Cell.

[4]  L. Öhman,et al.  Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions , 2010, Nature Reviews Gastroenterology &Hepatology.

[5]  T. Dinan,et al.  Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome , 2009, PloS one.

[6]  E. Mayer,et al.  Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel syndrome. , 2009, Gastroenterology.

[7]  T. Dinan,et al.  Irritable bowel syndrome: towards biomarker identification. , 2009, Trends in molecular medicine.

[8]  H. Strid,et al.  B‐cell activation in patients with irritable bowel syndrome (IBS) , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[9]  E. Mayer,et al.  Principles and clinical implications of the brain–gut–enteric microbiota axis , 2009, Nature Reviews Gastroenterology &Hepatology.

[10]  L. Öhman,et al.  T-Cell Activation in Patients With Irritable Bowel Syndrome , 2009, The American Journal of Gastroenterology.

[11]  J. Ceuppens,et al.  Immune dysfunction in patients with functional gastrointestinal disorders , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[12]  P. Scully,et al.  Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses , 2009, Biological Psychiatry.

[13]  J. Sheridan,et al.  Repeated social defeat activates dendritic cells and enhances Toll-like receptor dependent cytokine secretion , 2009, Brain, Behavior, and Immunity.

[14]  P. Baldi,et al.  Dysregulation of the hypothalamic‐pituitary‐adrenal (HPA) axis in irritable bowel syndrome , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[15]  J. Miao,et al.  Chronic restraint stress promotes immune suppression through Toll-like receptor 4-mediated phosphoinositide 3-kinase signaling , 2008, Journal of Neuroimmunology.

[16]  M. Kamm,et al.  Review article: the psychoneuroimmunology of irritable bowel syndrome – an exploration of interactions between psychological, neurological and immunological observations , 2008, Alimentary pharmacology & therapeutics.

[17]  R. Ji,et al.  Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord , 2008, The Journal of Neuroscience.

[18]  Baoxiang Zhao,et al.  Toll-like receptor 4 mediates chronic restraint stress-induced immune suppression , 2008, Journal of Neuroimmunology.

[19]  J. Sheridan,et al.  Repeated social defeat increases the bactericidal activity of splenic macrophages through a Toll-like receptor-dependent pathway. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

[20]  J. Corander,et al.  The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. , 2007, Gastroenterology.

[21]  A. Bowie,et al.  The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling , 2007, Nature Reviews Immunology.

[22]  Gerald Holtmann,et al.  Immune activation in patients with irritable bowel syndrome. , 2007, Gastroenterology.

[23]  P. Scully,et al.  Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? , 2006, Gastroenterology.

[24]  F. Liew,et al.  Negative regulation of Toll-like receptor-mediated immune responses , 2005, Nature Reviews Immunology.

[25]  E. Quigley.  Disturbances of motility and visceral hypersensitivity in irritable bowel syndrome: biological markers or epiphenomenon. , 2005, Gastroenterology clinics of North America.

[26]  M. Nishimura,et al.  Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. , 2005, Biological & pharmaceutical bulletin.

[27]  J. Kiecolt-Glaser,et al.  Stress-induced immune dysfunction: implications for health , 2005, Nature Reviews Immunology.

[28]  Shizuo Akira,et al.  Toll-like receptor signalling , 2004, Nature Reviews Immunology.

[29]  J. Cidlowski,et al.  Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression , 2004, Molecular and Cellular Biology.

[30]  Jiahuai Han,et al.  Glucocorticoids synergize with IL-1β to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells , 2004, BMC Molecular Biology.

[31]  Y. Taché,et al.  CRF1 receptor signaling pathways are involved in stress‐related alterations of colonic function and viscerosensitivity: implications for irritable bowel syndrome , 2004, British journal of pharmacology.

[32]  J. Buckingham,et al.  Cytokines: regulation of the hypothalamo-pituitary-adrenocortical axis. , 2003, Current opinion in pharmacology.

[33]  E. Quigley,et al.  Current Concepts of the Irritable Bowel Syndrome , 2003, Scandinavian journal of gastroenterology. Supplement.

[34]  D. Drossman,et al.  AGA technical review on irritable bowel syndrome. , 2002, Gastroenterology.

[35]  Wangxue Chen,et al.  Activation of the mucosal immune system in irritable bowel syndrome. , 2002, Gastroenterology.

[36]  E. Mayer,et al.  Evolving pathophysiologic models of functional gastrointestinal disorders. , 2002, Gastroenterology.

[37]  Y. Taché,et al.  Stress and the gastrointestinal tract III. Stress-related alterations of gut motor function: role of brain corticotropin-releasing factor receptors. , 2001, American journal of physiology. Gastrointestinal and liver physiology.

[38]  R. Spitzer,et al.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. , 1999, JAMA.

[39]  K W Heaton,et al.  Functional bowel disorders and functional abdominal pain , 1999, Gut.

[40]  P. Whorwell,et al.  The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress , 1997, Alimentary pharmacology & therapeutics.

[41]  G. Chrousos,et al.  The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. , 1995, The New England journal of medicine.

[42]  Wilfrid Jänig,et al.  Visceral nociceptors: a new world order? , 1992, Trends in Neurosciences.

[43]  R. Dantzer,et al.  From inflammation to sickness and depression: when the immune system subjugates the brain , 2008, Nature Reviews Neuroscience.

[44]  A. Craig,et al.  REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY Neuroimaging of the Brain-Gut Axis: From Basic Understanding to Treatment of Functional GI Disorders , 2006 .