Overexpression of HER2/neu oncogene in human pancreatic carcinoma.

[1]  H. Friess,et al.  p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis. , 1993, Cancer letters.

[2]  H. Friess,et al.  Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha. , 1992, The Journal of clinical investigation.

[3]  R. Koski,et al.  Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit , 1992, Cell.

[4]  Y. Yamanaka.  The immunohistochemical expressions of epidermal growth factors, epidermal growth factor receptors and c-erbB-2 oncoprotein in human pancreatic cancer. , 1992, Nihon Ika Daigaku zasshi.

[5]  P. Hall,et al.  Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer. , 1991, British Journal of Cancer.

[6]  K. Dobashi,et al.  Characterization of a neu/c-erbB-2 protein-specific activating factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[7]  S. Ménard,et al.  Prognostic significance of her‐2/neu expression in breast cancer and its relationship to other prognostic factors , 1991, International journal of cancer.

[8]  W. Gullick,et al.  c‐erbB‐2 proto‐oncogene expression and its relationship to survival in gastric carcinoma: An immunohistochemical study on archival material , 1991, International journal of cancer.

[9]  T. Kameda,et al.  Expression of ERBB2 in human gastric carcinomas: relationship between p185ERBB2 expression and the gene amplification. , 1990, Cancer research.

[10]  M. Ladanyi,et al.  Gene amplification in gastric and esophageal adenocarcinomas. , 1990, Cancer research.

[11]  L. Jarvis,et al.  The use of computer-assisted video image analysis in the enumeration of immuno-stained cells in tissue sections. , 1990, Journal of immunological methods.

[12]  T. Strohmeyer,et al.  Inverse relationship of epidermal growth factor receptor and HER2/neu gene expression in human renal cell carcinoma. , 1990, Cancer research.

[13]  N. Lemoine,et al.  The c‐erbB‐2 proto‐oncogene in human pancreatic cancer , 1990, The Journal of pathology.

[14]  M. Greene,et al.  Intermolecular association of the p185 neu protein and EGF receptor modulates EGF receptor function , 1990, Cell.

[15]  H. Roels,et al.  The neu‐oncogene protein as a predictive factor for haematogenous metastases in breast cancer patients , 1990, International journal of cancer.

[16]  W. Gullick,et al.  c‐erbB‐2 oncogene product staining in gastric adenocarcinoma. An immunohistochemical study , 1989, The Journal of pathology.

[17]  J. L. Bos,et al.  ras oncogenes in human cancer: a review. , 1989, Cancer research.

[18]  V. Brown,et al.  Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts , 1989, Cell.

[19]  W Godolphin,et al.  Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. , 1989, Science.

[20]  B Angus,et al.  Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer. , 1989, Cancer research.

[21]  A. Ullrich,et al.  HER2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor. , 1989, The EMBO journal.

[22]  M. J. van de Vijver,et al.  Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer. , 1988, The New England journal of medicine.

[23]  J. Stachura,et al.  Microvascular abnormalities of the portal hypertensive gastric mucosa , 1988, Hepatology.

[24]  R. Beazley,et al.  Update on pancreatic cancer , 1988, CA: a cancer journal for clinicians.

[25]  P. Nowell,et al.  Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Y. Shiloh,et al.  Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues. , 1988, Cancer research.

[27]  B. Groner,et al.  Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading. , 1988, Cancer research.

[28]  M. J. van de Vijver,et al.  Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene , 1987, Molecular and cellular biology.

[29]  M. Kraus,et al.  Overexpression of the EGF receptor‐related proto‐oncogene erbB‐2 in human mammary tumor cell lines by different molecular mechanisms. , 1987, The EMBO journal.

[30]  P. Meltzer,et al.  Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[31]  M. Yoshida,et al.  Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line , 1986, Molecular and cellular biology.

[32]  N. Nomura,et al.  Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor , 1986, Nature.

[33]  P. Seeburg,et al.  Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. , 1985, Science.

[34]  K. C. Reed,et al.  Rapid transfer of DNA from agarose gels to nylon membranes. , 1985, Nucleic acids research.

[35]  K. Semba,et al.  A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[36]  C R King,et al.  Amplification of a novel v-erbB-related gene in a human mammary carcinoma. , 1985, Science.

[37]  R. Weinberg,et al.  The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen , 1984, Nature.

[38]  J. Gutterman,et al.  Oncogene expression in human leukemia. , 1984, Blood.

[39]  W. Rutter,et al.  Pancreatic islet-acinar cell interaction: amylase messenger RNA levels ar determined by insulin. , 1981, Science.

[40]  R. Weinberg,et al.  Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts , 1981, Nature.

[41]  N. Blin,et al.  A general method for isolation of high molecular weight DNA from eukaryotes. , 1976, Nucleic acids research.

[42]  H. Friess,et al.  Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. , 1993, Anticancer research.