Predictive Factors for a Long Hospital Stay in Patients Undergoing Laparoscopic Cholecystectomy

Background. Although the advantages of laparoscopic cholecystectomy (LC) over open cholecystectomy are immediately obvious and appreciated, several patients need a postoperative hospital stay of more than 24 hours. Thus, the predictive factors for this longer stay need to be investigated. The aim of this study was to identify the causes of a long hospital stay after LC. Methods. This is a retrospective cohort study with 500 successful elective LC patients being included in the analysis. Short hospital stay was defined as being discharged within 24 hours after the operation, whereas long hospital stay was defined as the need for a stay of more than 24 hours after the operation. Results. Using multivariable analysis, ten independent predictive factors were identified for a long hospital stay. These included patients with cirrhosis, patients with a history of previous acute cholecystitis, cholangitis, or pancreatitis, patients on anticoagulation with warfarin, patients with standard-pressure pneumoperitoneum, patients who had been given metoclopramide as an intraoperative antiemetic drug, patients who had been using abdominal drain, patients who had numeric rating scale for pain > 3, patients with an oral analgesia requirement > 2 doses, complications, and private ward admission. Conclusions. LC difficulties were important predictive factors for a long hospital stay, as well as medication and operative factors.

[1]  Q. Nunes,et al.  Day case laparoscopic cholecystectomy in patients with high BMI: Experience from a UK centre. , 2016, Annals of the Royal College of Surgeons of England.

[2]  P. Pongchairerks,et al.  Combination of etoricoxib and low-pressure pneumoperitoneum versus standard treatment for the management of pain after laparoscopic cholecystectomy: a randomized controlled trial , 2016, Surgical Endoscopy.

[3]  R. Higa,et al.  Comparison between open and laparoscopic elective cholecystectomy in elderly, in a teaching hospital. , 2016, Revista do Colegio Brasileiro de Cirurgioes.

[4]  Jae Keun Kim,et al.  Influencing factors on postoperative hospital stay after laparoscopic cholecystectomy , 2016, Korean journal of hepato-biliary-pancreatic surgery.

[5]  O. Sadr-Azodi,et al.  Cholecystectomy in Patients with Liver Cirrhosis , 2015, Gastroenterology research and practice.

[6]  K. Chandacham,et al.  Metoclopramide, versus its combination with dexamethasone in the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: a double-blind randomized controlled trial. , 2015, Journal of the Medical Association of Thailand = Chotmaihet thangphaet.

[7]  Le Yao,et al.  Low-pressure versus standard-pressure pneumoperitoneum for laparoscopic cholecystectomy: a systematic review and meta-analysis. , 2014, American journal of surgery.

[8]  K. Inaba,et al.  Effect of delaying same‐admission cholecystectomy on outcomes in patients with diabetes , 2014, The British journal of surgery.

[9]  G. Kazemier,et al.  Meta‐analysis of laparoscopic versus open cholecystectomy for patients with liver cirrhosis and symptomatic cholecystolithiasis , 2013, The British journal of surgery.

[10]  N. Machado Laparoscopic Cholecystectomy in Cirrhotics , 2012, JSLS : Journal of the Society of Laparoendoscopic Surgeons.

[11]  X. Xiong,et al.  Efficacy of ondansetron vs. metoclopramide in prophylaxis of postoperative nausea and vomiting after laparoscopic cholecystectomy: a systematic review and meta-analysis. , 2012, Hepato-gastroenterology.

[12]  W. Marsden I and J , 2012 .

[13]  K. Nagpal,et al.  The impact of body mass index on outcomes after laparoscopic cholecystectomy , 2012, Surgical Endoscopy.

[14]  T. Sandhu,et al.  Effects of preemptive analgesia in laparoscopic cholecystectomy: a double-blind randomized controlled trial , 2010, Surgical Endoscopy.

[15]  T. Sandhu,et al.  Low-pressure pneumoperitoneum versus standard pneumoperitoneum in laparoscopic cholecystectomy, a prospective randomized clinical trial , 2008, Surgical Endoscopy.

[16]  T. Sandhu,et al.  Ondansetron versus metoclopramide in prophylaxis of nausea and vomiting for laparoscopic cholecystectomy: a prospective double-blind randomized study. , 2008, Asian journal of surgery.

[17]  Chien-Liang Liu,et al.  Factors associated with prolonged stay after laparoscopic cholecystectomy in elderly patients , 2008, Surgical Endoscopy.

[18]  H. Leong,et al.  Predictive factors of long hospital stay after laparoscopic cholecystectomy. , 2007, Asian journal of surgery.

[19]  C. Andrus,et al.  Laparoscopic cholecystectomy in anticoagulated patients , 2007, Surgical Endoscopy.

[20]  H. Gooszen,et al.  Laparoscopic versus open cholecystectomy for patients with symptomatic cholecystolithiasis. , 2006, The Cochrane database of systematic reviews.

[21]  J. Rosenberg,et al.  Preoperative Dexamethasone Improves Surgical Outcome After Laparoscopic Cholecystectomy: A Randomized Double-Blind Placebo-Controlled Trial , 2003, Annals of surgery.

[22]  M. Barczyński,et al.  A prospective randomized trial on comparison of low-pressure (LP) and standard-pressure (SP) pneumoperitoneum for laparoscopic cholecystectomy , 2003, Surgical Endoscopy And Other Interventional Techniques.

[23]  S. Ho,et al.  Small-Dose Dexamethasone Reduces Nausea and Vomiting After Laparoscopic Cholecystectomy: A Comparison of Tropisetron with Saline , 2002, Anesthesia and analgesia.

[24]  R. Porte,et al.  Laparoscopic Versus Open Cholecystectomy: A Prospective Matched-Cohort Study , 1996, HPB surgery : a world journal of hepatic, pancreatic and biliary surgery.

[25]  B. Maini,et al.  Laparoscopic cholecystectomy. A clinical and financial analysis of 280 operations. , 1992, Archives of surgery.

[26]  R Keane,et al.  Reduced postoperative hospitalization after laparoscopic cholecystectomy , 1991, The British journal of surgery.

[27]  R. Stephenson A and V , 1962, The British journal of ophthalmology.