Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

[1]  K. Jeong,et al.  Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride , 2019, Laboratory Animal Research.

[2]  J. Vilo,et al.  g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update) , 2019, Nucleic Acids Res..

[3]  D. DeNardo,et al.  Macrophages as regulators of tumour immunity and immunotherapy , 2019, Nature Reviews Immunology.

[4]  John M. Gaspar,et al.  NGmerge: merging paired-end reads via novel empirically-derived models of sequencing errors , 2018, BMC Bioinformatics.

[5]  F. Ginhoux,et al.  Inhibiting Inflammation with Myeloid Cell‐Specific Nanobiologics Promotes Organ Transplant Acceptance , 2018, Immunity.

[6]  L. Joosten,et al.  Trained immunity as a novel therapeutic strategy , 2018, Current opinion in pharmacology.

[7]  C. Bettegowda,et al.  Current state of immunotherapy for glioblastoma , 2018, Nature Reviews Clinical Oncology.

[8]  J. Kleeff,et al.  Therapeutic developments in pancreatic cancer: current and future perspectives , 2018, Nature Reviews Gastroenterology & Hepatology.

[9]  Bin Zhang,et al.  Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates , 2018, Nature Biomedical Engineering.

[10]  L. Joosten,et al.  Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity , 2018, Cell.

[11]  L. Joosten,et al.  Hypothesis: stimulation of trained immunity as adjunctive immunotherapy in cancer , 2017, Journal of leukocyte biology.

[12]  Nicholas A. Sinnott-Armstrong,et al.  An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues , 2017, Nature Methods.

[13]  R. Weinberg,et al.  Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells , 2017, The Journal of experimental medicine.

[14]  P. Greenberg,et al.  Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies. , 2017, Cancer cell.

[15]  J. Wargo,et al.  Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy , 2017, Cell.

[16]  Valerie A Longo,et al.  Immune cell screening of a nanoparticle library improves atherosclerosis therapy , 2016, Proceedings of the National Academy of Sciences.

[17]  L. Joosten,et al.  Immunometabolic circuits in trained immunity. , 2016, Seminars in immunology.

[18]  L. Zitvogel,et al.  Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors. , 2016, Immunity.

[19]  R. Xavier,et al.  Trained immunity: A program of innate immune memory in health and disease , 2016, Science.

[20]  M. Netea,et al.  BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study. , 2015, The Journal of infectious diseases.

[21]  Zahi A. Fayad,et al.  PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles , 2015, The Journal of Nuclear Medicine.

[22]  Qing-Yu He,et al.  ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization , 2015, Bioinform..

[23]  Piet Demeester,et al.  FlowSOM: Using self‐organizing maps for visualization and interpretation of cytometry data , 2015, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[24]  P. Sharma,et al.  The future of immune checkpoint therapy , 2015, Science.

[25]  Howard Y. Chang,et al.  ATAC‐seq: A Method for Assaying Chromatin Accessibility Genome‐Wide , 2015, Current protocols in molecular biology.

[26]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[27]  Taku Kambayashi,et al.  Atypical MHC class II-expressing antigen-presenting cells: can anything replace a dendritic cell? , 2014, Nature Reviews Immunology.

[28]  Valerie A Longo,et al.  A Modular Labeling Strategy for In Vivo PET and Near-Infrared Fluorescence Imaging of Nanoparticle Tumor Targeting , 2014, The Journal of Nuclear Medicine.

[29]  L. Kiemeney,et al.  Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer , 2014, PLoS pathogens.

[30]  M. Pfeffer,et al.  Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients with acute coronary syndromes: a randomized trial , 2014, European heart journal.

[31]  Howard Y. Chang,et al.  Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position , 2013, Nature Methods.

[32]  Sean C. Bendall,et al.  viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia , 2013, Nature Biotechnology.

[33]  M. Clarke,et al.  Intravital multiphoton imaging reveals multicellular streaming as a crucial component of in vivo cell migration in human breast tumors , 2013, Intravital.

[34]  D. Pardoll.  Immunology beats cancer: a blueprint for successful translation , 2012, Nature Immunology.

[35]  R. Xavier,et al.  Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes , 2012, Proceedings of the National Academy of Sciences.

[36]  Steven L Salzberg,et al.  Fast gapped-read alignment with Bowtie 2 , 2012, Nature Methods.

[37]  Yuen-Joyce Liu,et al.  Muramyl dipeptide and its derivatives: peptide adjuvant in immunological disorders and cancer therapy. , 2011, Current bioactive compounds.

[38]  David L. Porter,et al.  T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia , 2011, Science Translational Medicine.

[39]  M. Netea,et al.  Trained immunity: a memory for innate host defense. , 2011, Cell host & microbe.

[40]  Gaël Varoquaux,et al.  Scikit-learn: Machine Learning in Python , 2011, J. Mach. Learn. Res..

[41]  A. Tall,et al.  ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation , 2010, Science.

[42]  K. Craig,et al.  Coding of facial expressions of pain in the laboratory mouse , 2010, Nature Methods.

[43]  J. Cavaillon,et al.  Resilience to bacterial infection: difference between species could be due to proteins in serum. , 2010, The Journal of infectious diseases.

[44]  Jason S. Lewis,et al.  Standardized methods for the production of high specific-activity zirconium-89. , 2009, Nuclear medicine and biology.

[45]  P. Meyers.  Muramyl tripeptide (mifamurtide) for the treatment of osteosarcoma , 2009, Expert review of anticancer therapy.

[46]  Gonçalo R. Abecasis,et al.  The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..

[47]  Klaas Nicolay,et al.  Nanoparticulate assemblies of amphiphiles and diagnostically active materials for multimodality imaging. , 2009, Accounts of chemical research.

[48]  Clifford A. Meyer,et al.  Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.

[49]  P. Allavena,et al.  Cancer-related inflammation , 2008, Nature.

[50]  D. Philpott,et al.  Innate Immune Sensing of Microbes by Nod Proteins , 2006, Annals of the New York Academy of Sciences.

[51]  S. Akira,et al.  Pathogen Recognition and Innate Immunity , 2006, Cell.

[52]  M. Drouet,et al.  Nonhuman primates are relevant models for research in hematology, immunology and virology. , 2005, European cytokine network.

[53]  Polly Matzinger,et al.  Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses , 2004, Nature Reviews Immunology.

[54]  Z. Eshhar,et al.  Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[55]  J. Strominger,et al.  A modified colorimetric method for the estimation of N-acetylamino sugars. , 1955, The Journal of biological chemistry.

[56]  Vanessa M. Hubbard-Lucey,et al.  Comprehensive analysis of the clinical immuno-oncology landscape , 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

[57]  Tiffany J. Chen,et al.  Cytobank: providing an analytics platform for community cytometry data analysis and collaboration. , 2014, Current topics in microbiology and immunology.

[58]  Thomas R. Gingeras,et al.  STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..

[59]  K. P. Murphy,et al.  Janeway's immunobiology , 2007 .

[60]  C. Janeway,et al.  Innate immune recognition. , 2002, Annual review of immunology.