Design of an MRI-compatible modularized needle driver for In-bore MRI-guided prostate interventions

Magnetic resonance imaging (MRI) provides high-quality three dimensional visualization of prostate tissue, therefore MRI-guided prostate biopsy has been introduced to enhance cancer detection and treatment. However, closed-bore MRI has not been widely adopted for prostate interventions due to physical limitation of in-bore access and workspace. In this paper, we propose an MRI-compatible robotic manipulator which is able to perform both prostate biopsy and brachytherapy intervention in a closed-bore MRI scanner. The proposed manipulator mainly consists of a base robot and a needle driver. The needle driver can operate a conventional biopsy gun. The needle driver is draped separately from the base robot for sterilization, thus it can be detached from the base robot for needle replacing through a quick-release mechanism. Mechanical design and kinematic analysis of the robotic manipulator are delineated according to the constraints of the MRI environment and the clinical workflow.

[1]  G. Fichtinger,et al.  Development and Evaluation of an Actuated MRI-Compatible Robotic System for MRI-Guided Prostate Intervention , 2013, IEEE/ASME Transactions on Mechatronics.

[2]  Gabor Fichtinger,et al.  Robotic system for MRI-guided prostate biopsy: feasibility of teleoperated needle insertion and ex vivo phantom study , 2012, International Journal of Computer Assisted Radiology and Surgery.

[3]  Gabor Fichtinger,et al.  Real-time tracking of a bevel-tip needle with varying insertion depth: Toward teleoperated MRI-guided needle steering , 2013, 2013 IEEE/RSJ International Conference on Intelligent Robots and Systems.

[4]  Ken Masamune,et al.  System for robotically assisted prostate biopsy and therapy with intraoperative CT guidance. , 2002, Academic radiology.

[5]  Iulian Iordachita,et al.  Reconfigurable MRI-guided robotic surgical manipulator: Prostate brachytherapy and neurosurgery applications , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  K. Shinohara,et al.  Transrectal ultrasound guided prostatic nerve blockade eases systematic needle biopsy of the prostate. , 1996, The Journal of urology.

[7]  Gabor Fichtinger,et al.  Design of a novel MRI compatible manipulator for image guided prostate interventions , 2005, IEEE Transactions on Biomedical Engineering.

[8]  Nobuhiko Hata,et al.  Towards clinically optimized MRI-guided surgical manipulator for minimally invasive prostate percutaneous interventions: constructive design , 2013, 2013 IEEE International Conference on Robotics and Automation.

[9]  Gabor Fichtinger,et al.  Development of a pneumatic robot for MRI-guided transperineal prostate biopsy and brachytherapy: New approaches , 2010, 2010 IEEE International Conference on Robotics and Automation.

[10]  A. D'Amico,et al.  Real-time magnetic resonance image-guided interstitial brachytherapy in the treatment of select patients with clinically localized prostate cancer. , 1998, International journal of radiation oncology, biology, physics.

[11]  G.S. Fischer,et al.  MRI-Compatible Pneumatic Robot for Transperineal Prostate Needle Placement , 2008, IEEE/ASME Transactions on Mechatronics.

[12]  Katarzyna J Macura,et al.  MR-guided biopsy of the prostate: an overview of techniques and a systematic review. , 2008, European urology.

[13]  S. Zangos,et al.  MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results , 2004, European Radiology.

[14]  M. Terris,et al.  Comparison of mid-lobe versus lateral systematic sextant biopsies in the detection of prostate cancer. , 1997, Urologia internationalis.

[15]  A. Patriciu,et al.  A New Type of Motor: Pneumatic Step Motor , 2007, IEEE/ASME Transactions on Mechatronics.