A polymorphism in the chromosome 9p21 ANRIL locus is associated to Philadelphia positive acute lymphoblastic leukemia.

[1]  Xin Li,et al.  A risk-associated single nucleotide polymorphism of SMAD7 is common to colorectal, gastric, and lung cancers in a Han Chinese population , 2011, Molecular Biology Reports.

[2]  William R. Jeck,et al.  Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk , 2010, PLoS genetics.

[3]  James Allan,et al.  Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk , 2010, Nature Genetics.

[4]  Bernard Keavney,et al.  Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression , 2010, PLoS genetics.

[5]  Jonathan C. Cohen,et al.  Targeted Deletion of the 9p21 Noncoding Coronary Artery Disease Risk Interval in Mice , 2010, Nature.

[6]  Y. Kamatani,et al.  Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. , 2009, Gastroenterology.

[7]  J. Parker,et al.  Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus , 2009, Arteriosclerosis, thrombosis, and vascular biology.

[8]  Ching-Hon Pui,et al.  Germline genomic variants associated with childhood acute lymphoblastic leukemia , 2009, Nature Genetics.

[9]  E. Papaemmanuil,et al.  Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia , 2009, Nature Genetics.

[10]  Karen L. Mohlke,et al.  INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis , 2009, PloS one.

[11]  K. Jażdżewski,et al.  Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer , 2009, Proceedings of the National Academy of Sciences.

[12]  H. Shin,et al.  Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population , 2009, Diabetologia.

[13]  A. Singleton,et al.  Whole Genome Analyses Suggest Ischemic Stroke and Heart Disease Share an Association With Polymorphisms on Chromosome 9p21 , 2008, Stroke.

[14]  Stefan Lorkowski,et al.  Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. , 2008, Human molecular genetics.

[15]  H. Stefánsson,et al.  The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm , 2008, Nature Genetics.

[16]  A. Feinberg,et al.  Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA , 2008, Nature.

[17]  A. Berns,et al.  p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a , 2007, Nature.

[18]  C. Gieger,et al.  Genomewide association analysis of coronary artery disease. , 2007, The New England journal of medicine.

[19]  Simon C. Potter,et al.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.

[20]  Marcia M. Nizzari,et al.  Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels , 2007, Science.

[21]  M. McCarthy,et al.  Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes , 2007, Science.

[22]  S. Bandinelli,et al.  A common variant of the p16INK4a genetic region is associated with physical function in older people , 2007, Mechanisms of Ageing and Development.

[23]  I. Bièche,et al.  Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF. , 2007, Cancer research.

[24]  Daniel Sinnett,et al.  Promoter SNPs in G1/S checkpoint regulators and their impact on the susceptibility to childhood leukemia. , 2007, Blood.

[25]  N. Sharpless,et al.  The Regulation of INK4/ARF in Cancer and Aging , 2006, Cell.

[26]  C. Wahlestedt.  Natural antisense and noncoding RNA transcripts as potential drug targets. , 2006, Drug discovery today.

[27]  M. Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[28]  Nathaniel Rothman,et al.  Assessing the Probability That a Positive Report is False: An Approach for Molecular Epidemiology Studies , 2004 .

[29]  J. Rutka,et al.  The Cell Cycle: Accelerators, Brakes, and Checkpoints , 2004, Neurosurgery.

[30]  H. Cavé,et al.  CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono‐ and bi‐allelic 9p21 deletions in childhood acute lymphoblastic leukemia , 2003, Genes, chromosomes & cancer.

[31]  A. Ganser,et al.  Tumor suppressor genes in normal and malignant hematopoiesis , 2002, Oncogene.

[32]  Charles J. Sherr,et al.  The INK4a/ARF network in tumour suppression , 2001, Nature Reviews Molecular Cell Biology.

[33]  J. Rutka,et al.  The INK4A/ARF Locus: Role in Cell Cycle Control and Apoptosis and Implications for Glioma Growth , 2001, Journal of Neuro-Oncology.

[34]  D. Comings,et al.  Molecular heterosis: a review. , 2000, Molecular genetics and metabolism.

[35]  D. Johnson,et al.  Cyclins and cell cycle checkpoints. , 1999, Annual review of pharmacology and toxicology.

[36]  H. Drexler.  Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia–lymphoma cells , 1998, Leukemia.

[37]  H. Akaike.  A new look at the statistical model identification , 1974 .

[38]  C. Cantor,et al.  Automated genotyping using the DNA MassArray technology. , 2001, Methods in molecular biology.

[39]  G. Abecasis,et al.  Supporting Online Material Materials and Methods Figs. S1 to S8 Tables S1 to S10 References a Genome-wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants , 2022 .