论文信息 - Ethyl 6‐amino‐5‐cyano‐2‐methyl‐4‐phenyl‐4H‐pyran‐3‐carboxylate

Ethyl 6‐amino‐5‐cyano‐2‐methyl‐4‐phenyl‐4H‐pyran‐3‐carboxylate

The title compound, C16H16N2O3, was synthesized by the reaction of phenylmethylidenemalononitrile and ethyl acetoacetate in the presence of triethylbenzylammonium chloride in an aqueous medium. The pyran ring adopts a boat conformation. The phenyl ring and the basal plane of the pyran ring make a dihedral angle of 94.5 (2)°. Intermolecular N—H⋯O and N—H⋯N hydrogen bonds link the molecules into ribbons along the a axis.

[1] M. H. Elnagdi,et al. Nitriles in heterocyclic synthesis: novel synsthesis of benzo[c]-coumarin and of benzo[c]pyrano[3,2-c]quinoline derivatives , 1987 .

[2] Ronald Breslow,et al. Hydrophobic acceleration of Diels-Alder reactions , 1980 .

Ethyl 6‐amino‐5‐cyano‐2‐methyl‐4‐phenyl‐4H‐pyran‐3‐carboxyl­ate

Ethyl 6‐amino‐5‐cyano‐2‐methyl‐4‐phenyl‐4H‐pyran‐3‐carboxylate