Molecular Pathophysiology of Gout.
暂无分享,去创建一个
[1] H. Schumacher,et al. Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with gamma-linolenic acid and eicosapentaenoic acid. , 1988, Arthritis and rheumatism.
[2] T. Pincus,et al. Active and latent forms of transforming growth factor beta activity in synovial effusions , 1989, The Journal of experimental medicine.
[3] M. Walport,et al. Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. , 1989, The Journal of clinical investigation.
[4] J. Klein-Nulend,et al. Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production. , 1990, Journal of immunology.
[5] R. Thompson,et al. The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammation. , 1991, The American journal of pathology.
[6] M. Feldmann,et al. Induction of the interleukin 1 receptor antagonist protein by transforming growth factor‐β , 1991, European journal of immunology.
[7] S. McColl,et al. Human neutrophils produce high levels of the interleukin 1 receptor antagonist in response to granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha , 1992, The Journal of experimental medicine.
[8] S. Wahl,et al. Transforming growth factor-beta mediates IL-1-dependent induction of IL-1 receptor antagonist. , 1993, Journal of immunology.
[9] M. Rola-Pleszczynski,et al. Crystal-induced neutrophil activation. V. Differential production of biologically active IL-1 and IL-1 receptor antagonist. , 1994, Journal of immunology.
[10] A. Mantovani,et al. The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1. , 1994, Immunology today.
[11] A. Herbelin,et al. Inhibition and prevention of monosodium urate monohydrate crystal-induced acute inflammation in vivo by transforming growth factor beta1. , 1996, Arthritis and rheumatism.
[12] V. Fadok,et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. , 1998, The Journal of clinical investigation.
[13] C. Dinarello. The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. , 2000, The New England journal of medicine.
[14] M. Schiff,et al. Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis , 2000, Annals of the rheumatic diseases.
[15] A. Masuda,et al. Cutting Edge: Naturally Occurring Soluble Form of Mouse Toll-Like Receptor 4 Inhibits Lipopolysaccharide Signaling1 , 2000, The Journal of Immunology.
[16] Do junvenile idiopathic arthritis patients benefit from an exercise program? A pilot study. , 2001, Arthritis and rheumatism.
[17] M. Sweet,et al. A Novel Pathway Regulating Lipopolysaccharide-Induced Shock by ST2/T1 Via Inhibition of Toll-Like Receptor 4 Expression1 , 2001, The Journal of Immunology.
[18] J. Tschopp,et al. Regulation of Interleukin-1- and Lipopolysaccharide-Induced NF-κB Activation by Alternative Splicing of MyD88 , 2002, Current Biology.
[19] Y. Murakami,et al. Antiinflammatory effect of retrovirally transfected interleukin-10 on monosodium urate monohydrate crystal-induced acute inflammation in murine air pouches. , 2002, Arthritis and rheumatism.
[20] D. Kastner,et al. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. , 2003, Molecular cell.
[21] Su-Hua Huang,et al. A case-control study of the association of diet and obesity with gout in Taiwan. , 2003, The American journal of clinical nutrition.
[22] James E. Evans,et al. Molecular identification of a danger signal that alerts the immune system to dying cells , 2003, Nature.
[23] K. Miyake,et al. Interaction of Soluble Form of Recombinant Extracellular TLR4 Domain with MD-2 Enables Lipopolysaccharide Binding and Attenuates TLR4-Mediated Signaling1 , 2004, The Journal of Immunology.
[24] J. Schifferli,et al. Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis. , 2004, Blood.
[25] C. Serhan,et al. Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins1 , 2005, The Journal of Immunology.
[26] A. Yoshimura,et al. Negative regulation of cytokine signaling and immune responses by SOCS proteins , 2005, Arthritis research & therapy.
[27] F. Martinon,et al. Gout-associated uric acid crystals activate the NALP3 inflammasome , 2006, Nature.
[28] K. Fritsche. Fatty acids as modulators of the immune response. , 2006, Annual review of nutrition.
[29] M. Hayakawa,et al. ST2 suppresses IL-6 production via the inhibition of IkappaB degradation induced by the LPS signal in THP-1 cells. , 2006, Biochemical and biophysical research communications.
[30] J. Harton,et al. Pyrin-Only Protein 2 Modulates NF-κB and Disrupts ASC:CLR Interactions , 2007, The Journal of Immunology.
[31] J. Mages,et al. A genome-wide analysis of LPS tolerance in macrophages. , 2008, Immunobiology.
[32] J. Tschopp,et al. A pilot study of IL-1 inhibition by anakinra in acute gout , 2007, Arthritis research & therapy.
[33] A. Mansell,et al. The negative regulation of Toll‐like receptor and associated pathways , 2007, Immunology and cell biology.
[34] Geoff Bellingan,et al. Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyΔ12–14 PGJ2 , 2007, Proceedings of the National Academy of Sciences.
[35] C. Stehlik,et al. COPs and POPs: Modulators of Inflammasome Activity1 , 2007, The Journal of Immunology.
[36] P. Lamprecht,et al. Neue Aspekte zur Pathogenese der Gicht , 2008, Zeitschrift für Rheumatologie.
[37] C. Hess,et al. Polymorphonuclear Neutrophil-Derived Ectosomes Interfere with the Maturation of Monocyte-Derived Dendritic Cells1 , 2008, The Journal of Immunology.
[38] A. Till,et al. [New aspects of the pathogenesis of gout. Danger signals, autoinflammation and beyond]. , 2008, Zeitschrift fur Rheumatologie.
[39] S. Yamasaki,et al. Mincle is an ITAM-coupled activating receptor that senses damaged cells , 2008, Nature Immunology.
[40] Karan Sharma,et al. Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. , 2008, Immunity.
[41] Jun Xu,et al. Extracellular histones are major mediators of death in sepsis , 2009, Nature Medicine.
[42] S. Biswas,et al. Endotoxin tolerance: new mechanisms, molecules and clinical significance. , 2009, Trends in immunology.
[43] L. Wahl,et al. Endotoxin tolerance dysregulates MyD88‐ and Toll/IL‐1R domain‐containing adapter inducing IFN‐β‐dependent pathways and increases expression of negative regulators of TLR signaling , 2009, Journal of leukocyte biology.
[44] K. Scalapino,et al. Case of anakinra as a steroid-sparing agent for gout inflammation. , 2009, Arthritis and rheumatism.
[45] R. Terkeltaub,et al. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study , 2009, Annals of the rheumatic diseases.
[46] J. Scher,et al. The Anti-Inflammatory Effects of Prostaglandins , 2009, Journal of Investigative Medicine.
[47] J. Holroyd-Leduc,et al. Acute monoarthritis: What is the cause of my patient's painful swollen joint? , 2009, Canadian Medical Association Journal.
[48] Y. Zhang,et al. Endotoxin Tolerance of RAW264.7 Correlates with p38-dependent Up-regulation of Scavenger Receptor-A , 2009, The Journal of international medical research.
[49] Jillian Cornish,et al. Cellular characterization of the gouty tophus: a quantitative analysis. , 2010, Arthritis and rheumatism.
[50] S. Sadallah,et al. Ectosomes Released by Polymorphonuclear Neutrophils Induce a MerTK-dependent Anti-inflammatory Pathway in Macrophages* , 2010, The Journal of Biological Chemistry.
[51] K. Lauber,et al. Sodium Overload and Water Influx Activate the NALP3 Inflammasome , 2010, The Journal of Biological Chemistry.
[52] J. Sévigny,et al. Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro. , 2010, Molecular immunology.
[53] B. Palmer,et al. Interleukin 37 is a fundamental inhibitor of innate immunity , 2010, Nature Immunology.
[54] T. Neogi. Clinical practice. Gout. , 2011, The New England journal of medicine.
[55] Shin-Seok Lee,et al. Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis , 2011, Arthritis research & therapy.
[56] Roddy Edward,et al. Gout , 2011 .
[57] Cheng-Han Wu,et al. Spontaneous resolution of acute gouty arthritis is associated with rapid induction of the anti-inflammatory factors TGFβ1, IL-10 and soluble TNF receptors and the intracellular cytokine negative regulators CIS and SOCS3 , 2011, Annals of the rheumatic diseases.
[58] C. Jun,et al. Eupatilin inhibits lipopolysaccharide-induced expression of inflammatory mediators in macrophages. , 2011, Life sciences.
[59] S. Steiger,et al. Monosodium urate monohydrate crystal-recruited noninflammatory monocytes differentiate into M1-like proinflammatory macrophages in a peritoneal murine model of gout. , 2011, Arthritis and rheumatism.
[60] R. Terkeltaub,et al. 2012 American College of Rheumatology guidelines for management of gout. Part 2: Therapy and antiinflammatory prophylaxis of acute gouty arthritis , 2012, Arthritis care & research.
[61] L. Punzi,et al. Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phase , 2012, Annals of the rheumatic diseases.
[62] P. Thompson,et al. Activation of PAD4 in NET formation , 2012, Front. Immun..
[63] Charles King,et al. 2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia , 2012, Arthritis care & research.
[64] M. Spite,et al. Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids. , 2012, Annual review of nutrition.
[65] Richard A. Flavell,et al. Inflammasomes in health and disease , 2012, Nature.
[66] G. Gamble,et al. The Effects of Monosodium Urate Monohydrate Crystals on Chondrocyte Viability and Function: Implications for Development of Cartilage Damage in Gout , 2013, The Journal of Rheumatology.
[67] Kazuro Furukawa,et al. TLR4–MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide , 2013, Proceedings of the National Academy of Sciences.
[68] C. Reis e Sousa,et al. Sensing of cell death by myeloid C-type lectin receptors. , 2013, Current opinion in immunology.
[69] Zhigang Tian,et al. Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. , 2013, Immunity.
[70] M. Röhm,et al. NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury , 2013, Front. Immunol..
[71] B. Fadeel,et al. Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process , 2013, The Journal of Immunology.
[72] S. Steiger,et al. Neutrophil cannibalism triggers transforming growth factor β1 production and self regulation of neutrophil inflammatory function in monosodium urate monohydrate crystal-induced inflammation in mice. , 2013, Arthritis and rheumatism.
[73] G. Gardner,et al. Treatment of Acute Gouty Arthritis in Complex Hospitalized Patients With Anakinra , 2013, Arthritis care & research.
[74] B. Stockwell,et al. Regulated cell death and inflammation: an auto-amplification loop causes organ failure , 2014, Nature Reviews Immunology.
[75] K. Nakagomi,et al. Proteomic Analysis to Examine the Role of Matrix Proteins in a Gouty Tophus from a Patient with Recurrent Gout , 2014, Nucleosides, nucleotides & nucleic acids.
[76] G. Berry,et al. T Cell–Macrophage Interactions and Granuloma Formation in Vasculitis , 2014, Front. Immunol..
[77] T. Harrer,et al. Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines , 2014, Nature Medicine.
[78] B. Kuster,et al. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. , 2014, Immunity.
[79] P. Vandenabeele,et al. Regulated necrosis: the expanding network of non-apoptotic cell death pathways , 2014, Nature Reviews Molecular Cell Biology.
[80] P. Detampel,et al. Activation of NLRP3 inflammasome by crystalline structures via cell surface contact , 2014, Scientific Reports.
[81] W. Robinson,et al. Contribution of Mast Cell–Derived Interleukin‐1β to Uric Acid Crystal–Induced Acute Arthritis in Mice , 2014, Arthritis & rheumatology.
[82] Mei Zeng,et al. IL-37 inhibits the production of pro-inflammatory cytokines in MSU crystal-induced inflammatory response , 2016, Clinical Rheumatology.
[83] H. Anders,et al. Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN. , 2015, Journal of the American Society of Nephrology : JASN.
[84] E. Gertner,et al. Anakinra for the treatment of acute severe gout in critically ill patients. , 2015, Seminars in arthritis and rheumatism.
[85] G. Schett,et al. Why does the gout attack stop? A roadmap for the immune pathogenesis of gout , 2015, RMD Open.
[86] Joo-Hyun Lee,et al. Application of a Novel Diagnostic Rule in the Differential Diagnosis between Acute Gouty Arthritis and Septic Arthritis , 2015, Journal of Korean medical science.
[87] A. Dumusc,et al. Interleukin-1 as a therapeutic target in gout , 2015, Current opinion in rheumatology.
[88] A. Aouba,et al. Efficacy of Anakinra for Various Types of Crystal-Induced Arthritis in Complex Hospitalized Patients: A Case Series and Review of the Literature , 2015, Mediators of inflammation.
[89] O. Shaw,et al. Role of miR-146a in regulation of the acute inflammatory response to monosodium urate crystals , 2015, Annals of the rheumatic diseases.
[90] N. Dalbeth,et al. The Gouty Tophus: a Review , 2015, Current Rheumatology Reports.
[91] J. Schifferli,et al. Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome , 2015, Annals of the rheumatic diseases.
[92] E. Latz,et al. Crystal Formation in Inflammation. , 2016, Annual review of immunology.
[93] B. Beutler,et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component , 2015, Nature Immunology.
[94] J. Hahn,et al. Neutrophils and neutrophil extracellular traps orchestrate initiation and resolution of inflammation. , 2016, Clinical and experimental rheumatology.
[95] G. Núñez,et al. Nek7 is an essential mediator of NLRP3 activation downstream of potassium efflux , 2016, Nature.
[96] H. Anders,et al. Necroinflammation in Kidney Disease. , 2016, Journal of the American Society of Nephrology.
[97] Xiaoxia Zhu,et al. Interleukin 37 limits monosodium urate crystal-induced innate immune responses in human and murine models of gout , 2016, Arthritis Research & Therapy.
[98] M. Gutierrez,et al. Monosodium urate crystals induce oxidative stress in human synoviocytes , 2016, Arthritis Research & Therapy.
[99] Balázs Rada,et al. Macrophage-derived IL-1β enhances monosodium urate crystal-triggered NET formation , 2016, Inflammation Research.
[100] Rostyslav Bilyy,et al. Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis , 2016, Nature Communications.
[101] H. Anders,et al. PMA and crystal‐induced neutrophil extracellular trap formation involves RIPK1‐RIPK3‐MLKL signaling , 2016, European journal of immunology.
[102] Trevor A. Mori,et al. Specialised pro-resolving mediators of inflammation in inflammatory arthritis. , 2016, Prostaglandins, leukotrienes, and essential fatty acids.
[103] Wen-tian He,et al. Necrosome core machinery: MLKL , 2016, Cellular and Molecular Life Sciences.
[104] J. M. Brauner,et al. New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation , 2016, Front. Immunol..
[105] L. Joosten,et al. Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases , 2015, Annals of the rheumatic diseases.
[106] L. Macia,et al. Dietary fiber and the short‐chain fatty acid acetate promote resolution of neutrophilic inflammation in a model of gout in mice , 2017, Journal of leukocyte biology.
[107] J. Sokolove,et al. P2Y6 Receptor Antagonist MRS2578 Inhibits Neutrophil Activation and Aggregated Neutrophil Extracellular Trap Formation Induced by Gout-Associated Monosodium Urate Crystals , 2017, The Journal of Immunology.
[108] B. Mandell,et al. Update on Crystal-Induced Arthritides. , 2017, Clinics in geriatric medicine.
[109] M. Doherty,et al. Gout - a guide for the general and acute physicians. , 2017, Clinical medicine.