S1P/S1PR2 promote pancreatic stellate cell activation and pancreatic fibrosis in chronic pancreatitis by regulating autophagy and the NLRP3 inflammasome.
暂无分享,去创建一个
Shukun Zhang | Caixia Li | Lihua Cui | Lanqiu Zhang | Yu-zhen Zhuo | N. Cui | Guixian Zhang | Guowang Yao
[1] Jing Yang,et al. Sphingosine 1-phosphate receptor 2 mediated early stages of pancreatic and systemic inflammatory responses via NF-kappa B activation in acute pancreatitis , 2022, Cell Communication and Signaling.
[2] S. Scala,et al. Sphingosine‐1‐phosphate/TGF‐β axis drives epithelial mesenchymal transition in asthma‐like disease , 2021, British journal of pharmacology.
[3] C. Lee,et al. S1P/S1P2 Signaling Axis Regulates Both NLRP3 Upregulation and NLRP3 Inflammasome Activation in Macrophages Primed with Lipopolysaccharide , 2021, Antioxidants.
[4] R. Paroni,et al. Spns2 Transporter Contributes to the Accumulation of S1P in Cystic Fibrosis Human Bronchial Epithelial Cells , 2021, Biomedicines.
[5] Shukun Zhang,et al. Role of NLR Family Pyrin Domain-Containing 3 Inflammasome in the Activation of Pancreatic Stellate Cells. , 2021, Experimental cell research.
[6] S. Góźdź,et al. Hypogelsolinemia and Decrease in Blood Plasma Sphingosine-1-Phosphate in Patients Diagnosed with Severe Acute Pancreatitis , 2021, Digestive Diseases and Sciences.
[7] Chang Xu,et al. S1PR2 Inhibition Attenuates Allergic Asthma Possibly by Regulating Autophagy , 2021, Frontiers in Pharmacology.
[8] Liying Li,et al. Macrophage Sphingosine 1-Phosphate Receptor 2 Blockade Attenuates Liver Inflammation and Fibrogenesis Triggered by NLRP3 Inflammasome , 2020, Frontiers in Immunology.
[9] Shukun Zhang,et al. Saikosaponin A inhibits the activation of pancreatic stellate cells by suppressing autophagy and the NLRP3 inflammasome via the AMPK/mTOR pathway. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[10] Y. Miao,et al. Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-κB pathway. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[11] Mingyuan Liu,et al. Activation of ROS/MAPKs/NF‐κB/NLRP3 and inhibition of efferocytosis in osteoclast‐mediated diabetic osteoporosis , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[12] G. Homuth,et al. NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-inflammatory Response Syndromes in Mice With Acute Pancreatitis. , 2019, Gastroenterology.
[13] Shukun Zhang,et al. Saikosaponin d ameliorates pancreatic fibrosis by inhibiting autophagy of pancreatic stellate cells via PI3K/Akt/mTOR pathway. , 2019, Chemico-biological interactions.
[14] M. Zeng,et al. The Role of S1P and the Related Signaling Pathway in the Development of Tissue Fibrosis , 2019, Front. Pharmacol..
[15] J. Ritter,et al. Sphingosine-1-phosphate pathway in renal fibrosis. , 2018, American journal of physiology. Renal physiology.
[16] N. S. Yarla,et al. Regulatory role of sphingosine kinase and sphingosine-1-phosphate receptor signaling in progenitor/stem cells , 2018, World journal of stem cells.
[17] Gang Wang,et al. RB1CC1-enhanced autophagy facilitates PSCs activation and pancreatic fibrogenesis in chronic pancreatitis , 2018, Cell Death & Disease.
[18] Shukun Zhang,et al. Inhibiting autophagy promotes collagen degradation by regulating matrix metalloproteinases in pancreatic stellate cells , 2018, Life sciences.
[19] Min Chen,et al. Rho GTPases are involved in S1P‐enhanced glomerular endothelial cells activation with anti‐myeloperoxidase antibody positive IgG , 2018, Journal of cellular and molecular medicine.
[20] Fan Wang,et al. Sphingosine 1 phosphate receptor-1 (S1PR1) signaling protects cardiac function by inhibiting cardiomyocyte autophagy , 2018, Journal of geriatric cardiology : JGC.
[21] A. Wree,et al. NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL‐17 and TNF in mice , 2018, Hepatology.
[22] A. Dabrowski,et al. Plasma Sphingolipids in Acute Pancreatitis , 2017, International journal of molecular sciences.
[23] Guiming Zhang,et al. P2X7R Blockade Prevents NLRP3 Inflammasome Activation and Pancreatic Fibrosis in a Mouse Model of Chronic Pancreatitis , 2017, Pancreas.
[24] M. Hashizume,et al. Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice. , 2017, Gastroenterology.
[25] I. Noth,et al. Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy , 2015, Thorax.
[26] M. Baranowski,et al. Sources, metabolism, and regulation of circulating sphingosine-1-phosphate , 2015, Journal of Lipid Research.
[27] V. Shah,et al. Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. , 2014, The American journal of pathology.
[28] C. Corrigan,et al. Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells , 2014, Allergy.
[29] D. Klionsky. Coming soon to a journal near you—The updated guidelines for the use and interpretation of assays for monitoring autophagy , 2014, Autophagy.
[30] R. Takayanagi,et al. A sustained prostacyclin analog, ONO-1301, attenuates pancreatic fibrosis in experimental chronic pancreatitis induced by dibutyltin dichloride in rats. , 2014, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
[31] S. Yue,et al. Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis. , 2013, Journal of hepatology.
[32] R. Stevens,et al. Sphingosine-1-phosphate and its receptors: structure, signaling, and influence. , 2013, Annual review of biochemistry.
[33] M. Bolli,et al. Sphingosine 1-Phosphate (S1P) Receptor Agonists Mediate Pro-fibrotic Responses in Normal Human Lung Fibroblasts via S1P2 and S1P3 Receptors and Smad-independent Signaling , 2013, The Journal of Biological Chemistry.
[34] H. Friess,et al. StellaTUM: current consensus and discussion on pancreatic stellate cell research , 2011, Gut.
[35] Liying Li,et al. Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility. , 2011, Journal of hepatology.
[36] Hong-Wei Li,et al. Cardiac fibrosis in diabetic rats: regulation and mechanism of activation of the PPARgamma signal pathway. , 2010, The Chinese journal of physiology.
[37] H. Witt,et al. Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. , 2007, Gastroenterology.
[38] H. Nawata,et al. The Role of Monocyte Chemoattractant Protein-1 in Experimental Chronic Pancreatitis Model Induced by Dibutyltin Dichloride in Rats , 2002, Pancreas.
[39] D. Stainier,et al. A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development , 2000, Nature.