Insights into the Proteome of Gastrointestinal Stromal Tumors-Derived Exosomes Reveals New Potential Diagnostic Biomarkers*
暂无分享,去创建一个
Andrew K Godwin | M. Merchant | A. Godwin | M. Milhem | Daniel W. Wilkey | Michael Merchant | Safinur Atay | Mohammed Milhem | Daniel W Wilkey | S. Atay | D. Wilkey
[1] G. Willmott,et al. Pulse Size Distributions in Tunable Resistive Pulse Sensing. , 2016, Analytical chemistry.
[2] K. Yuyama,et al. Accelerated release of exosome‐associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1‐induced amyloid fibril formation , 2008, Journal of neurochemistry.
[3] C. Théry,et al. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. , 2014, Annual review of cell and developmental biology.
[4] A. Mason,et al. Exosome formation during maturation of mammalian and avian reticulocytes: Evidence that exosome release is a major route for externalization of obsolete membrane proteins , 1991, Journal of cellular physiology.
[5] Kristin E. Burnum-Johnson,et al. Proteomic Profiling of Exosomes Leads to the Identification of Novel Biomarkers for Prostate Cancer , 2013, PloS one.
[6] K. Chayama,et al. Hypoxia-inducible factor-1α expression and angiogenesis in gastrointestinal stromal tumor of the stomach , 2003 .
[7] R. Goldberg,et al. New targeted therapies in gastrointestinal cancers , 2003, Current treatment options in oncology.
[8] J. Suttles,et al. Trophoblast‐Derived Exosomes Mediate Monocyte Recruitment and Differentiation , 2011, American journal of reproductive immunology.
[9] A. Hill,et al. A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing , 2016, Journal of extracellular vesicles.
[10] J. Klein,et al. Microfiltration isolation of human urinary exosomes for characterization by MS , 2010, Proteomics. Clinical applications.
[11] M. Katoh,et al. FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells. , 2006, International journal of molecular medicine.
[12] Xin Wu,et al. CD133 and Ki-67 expression is associated with gastrointestinal stromal tumor prognosis , 2013, Oncology letters.
[13] Giuseppe Floris,et al. Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST) , 2010, Proceedings of the National Academy of Sciences.
[14] Juan Antonio Vizcaíno,et al. The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition , 2016, Nucleic Acids Res..
[15] Bart N Lambrecht,et al. Proteomic analysis of exosomes isolated from human malignant pleural effusions. , 2004, American journal of respiratory cell and molecular biology.
[16] W. H. Kim,et al. Characteristics of KIT-negative gastrointestinal stromal tumours and diagnostic utility of protein kinase C theta immunostaining , 2007, Journal of Clinical Pathology.
[17] Alexey I Nesvizhskii,et al. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. , 2002, Analytical chemistry.
[18] S. Atay,et al. Human Trophoblast‐Derived Exosomal Fibronectin Induces Pro‐Inflammatory Il‐1β Production by Macrophages , 2011, American journal of reproductive immunology.
[19] M. Platt,et al. Tunable resistive pulse sensing: potential applications in nanomedicine. , 2016, Nanomedicine.
[20] Jacopo Meldolesi,et al. Shedding microvesicles: artefacts no more. , 2009, Trends in cell biology.
[21] A. Saito,et al. Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress. , 2016, Biochemical and biophysical research communications.
[22] J. Lasota,et al. Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. , 2009, Archives of pathology & laboratory medicine.
[23] N. Karp,et al. Design and Analysis Issues in Quantitative Proteomics Studies , 2007, Proteomics.
[24] Christian Pilarsky,et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer , 2015, Nature.
[25] T. Pisitkun,et al. Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers , 2017, PloS one.
[26] H. Tsuda,et al. Pfetin as a prognostic biomarker for gastrointestinal stromal tumor: validation study in multiple clinical facilities. , 2011, Japanese journal of clinical oncology.
[27] W. Sly,et al. Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors , 2010, Modern Pathology.
[28] J. Fletcher,et al. Protein Kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs). , 2004, Cancer research.
[29] A. Godwin,et al. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion , 2013, Proceedings of the National Academy of Sciences.
[30] C. Fletcher,et al. Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution. , 2002, American journal of clinical pathology.
[31] M. Tong,et al. Flow speed alters the apparent size and concentration of particles measured using NanoSight nanoparticle tracking analysis. , 2016, Placenta.
[32] T. Pisitkun,et al. Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation* , 2016, Molecular & Cellular Proteomics.
[33] C. Théry. Exosomes: secreted vesicles and intercellular communications , 2011, F1000 biology reports.
[34] Andrew K Godwin,et al. Response markers and the molecular mechanisms of action of Gleevec in gastrointestinal stromal tumors. , 2003, Molecular cancer therapeutics.
[35] Samuel Singer,et al. PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors , 2003, Science.
[36] T. Shuin,et al. Conventional and Molecular Cytogenetic Characterization of a New Human Cell Line, GIST-T1, Established from Gastrointestinal Stromal Tumor , 2002, Laboratory Investigation.
[37] Kristie L. Rose,et al. Proteomics characterization of exosome cargo. , 2015, Methods.
[38] Weijia Xie,et al. Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer , 2016, Oncotarget.
[39] R. Herings,et al. Incidence of gastrointestinal stromal tumours is underestimated: results of a nation-wide study. , 2005, European journal of cancer.
[40] Hamid Cheshmi. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers , 2011 .
[41] T. Kislinger,et al. Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. , 2013, Experimental cell research.
[42] C. Metzner,et al. Integrated Method for Purification and Single-Particle Characterization of Lentiviral Vector Systems by Size Exclusion Chromatography and Tunable Resistive Pulse Sensing , 2017, Molecular Biotechnology.
[43] Emergence of Secondary Resistance to Imatinib in Recurrent Gastric GIST , 2010, Journal of Gastrointestinal Surgery.
[44] G. Parmiani,et al. Tumor-released microvesicles as vehicles of immunosuppression. , 2007, Cancer research.
[45] J. Fletcher,et al. Protein Kinase C θ (PKCθ) Expression and Constitutive Activation in Gastrointestinal Stromal Tumors (GISTs) , 2004, Cancer Research.
[46] Vasco Filipe,et al. Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates , 2010, Pharmaceutical Research.
[47] S. Pilotti,et al. The CD133 expression levels and its role as potential cancer stem cells marker in gastrointestinal stromal tumor , 2012, International journal of cancer.
[48] M. Heinrich,et al. PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[49] Clotilde Théry,et al. Biogenesis and secretion of exosomes. , 2014, Current opinion in cell biology.
[50] J. Ioannidis,et al. Epidemiologic design and analysis for proteomic studies: a primer on -omic technologies. , 2015, American journal of epidemiology.
[51] Tina Hernandez-Boussard,et al. Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles , 2004, Oncogene.
[52] J. Fletcher,et al. Protein kinase C-θ regulates KIT expression and proliferation in gastrointestinal stromal tumors , 2008, Oncogene.
[53] B. Geoerger,et al. Proteomic Analysis of Neuroblastoma‐Derived Exosomes: New Insights into a Metastatic Signature , 2017, Proteomics.
[54] A. Godwin,et al. Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms. , 2006, Cancer research.
[55] S. Hirohashi,et al. Pfetin as a prognostic biomarker in gastrointestinal stromal tumor: novel monoclonal antibody and external validation study in multiple clinical facilities. , 2010, Japanese journal of clinical oncology.
[56] J. Lea,et al. Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies: a proof of concept study , 2017, Oncotarget.
[57] K. Hunt,et al. Gastrointestinal stromal tumors: overview of pathologic features, molecular biology, and therapy with imatinib mesylate. , 2004, Histology and histopathology.
[58] L. Saieva,et al. Contribution of proteomics to understanding the role of tumor‐derived exosomes in cancer progression: State of the art and new perspectives , 2014, Proteomics.
[59] Massimo Spada,et al. High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients , 2009, PloS one.
[60] L. Bujanda,et al. Glypican-1 in exosomes as biomarker for early detection of pancreatic cancer. , 2016, Annals of translational medicine.
[61] R. West,et al. DOG1 for the Diagnosis of Gastrointestinal Stromal Tumor (GIST): Comparison Between 2 Different Antibodies , 2010, Applied immunohistochemistry & molecular morphology : AIMM.
[62] A. Godwin,et al. Exosomes as mediators of platinum resistance in ovarian cancer , 2017, Oncotarget.
[63] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[64] H. Hassan. c-Kit expression in human normal and malignant stem cells prognostic and therapeutic implications. , 2009, Leukemia research.
[65] H. Hoogsteden,et al. Proteomic analysis of exosomes secreted by human mesothelioma cells. , 2004, The American journal of pathology.
[66] C. Eyers. Universal sample preparation method for proteome analysis , 2009 .
[67] Jina Ko,et al. Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices. , 2016, The Analyst.
[68] T. Whiteside,et al. Tumour-derived exosomes or microvesicles: another mechanism of tumour escape from the host immune system? , 2005, British Journal of Cancer.
[69] M. Merchant,et al. Comparison of Proteins Expressed on Secretory Vesicle Membranes and Plasma Membranes of Human Neutrophils1 , 2008, The Journal of Immunology.
[70] M. Vidal,et al. Proteomic analysis of secreted exosomes. , 2007, Sub-cellular biochemistry.
[71] M. Kesimer,et al. Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. , 2011, Experimental cell research.
[72] P. Selby,et al. Proteomic analysis of melanoma‐derived exosomes by two‐dimensional polyacrylamide gel electrophoresis and mass spectrometry , 2004, Proteomics.
[73] P. Lievens,et al. Cell adaptation to activated FGFR3 includes Sprouty4 up regulation to inhibit the receptor‐mediated ERKs activation from the endoplasmic reticulum , 2009, FEBS Letters.
[74] J. Clifton,et al. Proteomic analysis for process development and control of therapeutic protein separation from human plasma , 2009, Electrophoresis.
[75] A. Prestipino,et al. Gastrointestinal Stromal Tumors: A Review. , 2016, American journal of therapeutics.
[76] Steven P Gygi,et al. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry , 2007, Nature Methods.
[77] Matko Bosnjak,et al. REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms , 2011, PloS one.
[78] A. Godwin. Bench to Bedside and Back Again: Personalizing Treatment for Patients with GIST , 2011, Molecular Cancer Therapeutics.
[79] S. Hirota,et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. , 1998, Science.
[80] Meredith C Henderson,et al. The Genomic and Proteomic Content of Cancer Cell-Derived Exosomes , 2011, Front. Oncol..
[81] David Botstein,et al. Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. , 2003, The American journal of pathology.
[82] K. Kishi,et al. Expression of the c‐kit gene product in normal and neoplastic mast cells but not in neoplastic basophil/mast cell precursors from chronic myelogenous leukaemia , 1995, The Journal of pathology.
[83] W. Schmiegel,et al. Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. , 2011, Life sciences.
[84] Veronica Huber,et al. Induction of Lymphocyte Apoptosis by Tumor Cell Secretion of FasL-bearing Microvesicles , 2002, The Journal of experimental medicine.
[85] Guanming Wu,et al. ReactomeFIViz : a Cytoscape app for pathway and network-based data analysis , 2022 .
[86] G. Siegwart,et al. Sprouty4 levels are increased under hypoxic conditions by enhanced mRNA stability and transcription , 2010, Biological chemistry.
[87] N. Raab-Traub,et al. Human tumor virus utilizes exosomes for intercellular communication , 2010, Proceedings of the National Academy of Sciences.
[88] Wei Xiong,et al. Role of tumor microenvironment in tumorigenesis , 2017, Journal of Cancer.
[89] G. Stein,et al. Proteomic Analysis of Exosomes and Exosome‐Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression , 2016, Journal of cellular biochemistry.
[90] R. Roden,et al. Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer , 2009, BMC Cancer.
[91] G. Kristiansen,et al. Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM. , 2007, Gynecologic oncology.
[92] G. Illei,et al. The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes , 2012, PloS one.
[93] S. Bessa,et al. Evaluation of the Novel Monoclonal Antibody Against DOG1 as a Diagnostic Marker for Gastrointestinal Stromal Tumors. , 2009, Journal of the Egyptian National Cancer Institute.
[94] S. Mathivanan,et al. Exosomes: extracellular organelles important in intercellular communication. , 2010, Journal of proteomics.
[95] R. Simpson,et al. Proteomic insights into extracellular vesicle biology – defining exosomes and shed microvesicles , 2017, Expert review of proteomics.
[96] Paul J. Zhang,et al. Hypoxia-Inducible Factors: Mediators of Cancer Progression; Prognostic and Therapeutic Targets in Soft Tissue Sarcomas , 2013, Cancers.
[97] G. McAlister,et al. Decision tree–driven tandem mass spectrometry for shotgun proteomics , 2008, Nature Methods.
[98] K. Chayama,et al. Hypoxia-inducible factor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach. , 2003, Oncology reports.
[99] P. Altevogt,et al. Body fluid derived exosomes as a novel template for clinical diagnostics , 2011, Journal of Translational Medicine.
[100] N. Wong,et al. A study of α5 chain of collagen IV, caldesmon, placental alkaline phosphatase and smoothelin as immunohistochemical markers of gastrointestinal smooth muscle neoplasms , 2013, Journal of Clinical Pathology.
[101] S. Hirota,et al. Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors. , 2003, Gastroenterology.
[102] L. Sobin,et al. Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases. , 2000, The American journal of pathology.
[103] Douglas D. Taylor,et al. Shed membrane fragment-associated markers for endometrial and ovarian cancers. , 2002, Gynecologic oncology.
[104] H. Matsubara,et al. Quantification of plasma exosome is a potential prognostic marker for esophageal squamous cell carcinoma , 2016, Oncology reports.
[105] Juliane Nguyen,et al. Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[106] M. Herlyn,et al. Melanoma exosomes: messengers of metastasis , 2012, Nature Medicine.
[107] D. Taylor,et al. Shedding of plasma membrane fragments. Neoplastic and developmental importance. , 1986, Developmental biology.
[108] M. Loda,et al. Gastrointestinal stromal tumors I: pathology, pathobiology, primary therapy, and surgical issues. , 2009, Seminars in oncology.
[109] M. Pierotti,et al. High CD133 expression levels in gastrointestinal stromal tumors , 2011, Cytometry. Part B, Clinical cytometry.
[110] Adrian Preda,et al. Prostate cancer proteomics: Current trends and future perspectives for biomarker discovery , 2017, Oncotarget.
[111] Marco Y. Hein,et al. The Perseus computational platform for comprehensive analysis of (prote)omics data , 2016, Nature Methods.
[112] R. Aebersold,et al. A statistical model for identifying proteins by tandem mass spectrometry. , 2003, Analytical chemistry.
[113] S. Hanash,et al. Impact of Protein Stability, Cellular Localization, and Abundance on Proteomic Detection of Tumor-Derived Proteins in Plasma , 2011, PloS one.
[114] J. Lötvall,et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.
[115] T. Rasmussen,et al. Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer , 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[116] Adrian A Canutescu,et al. Analysis of KIT Mutations in Sporadic and Familial Gastrointestinal Stromal Tumors: Therapeutic Implications through Protein Modeling , 2005, Clinical Cancer Research.
[117] C. Antonescu,et al. Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation , 2005, Clinical Cancer Research.
[118] J. Licht,et al. Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop. , 2004, Molecular biology of the cell.
[119] A. Yoshimura,et al. Mammalian Sprouty4 Suppresses Ras-Independent ERK Activation by Binding to Raf1 , 2003, Cell cycle.
[120] R. Setterquist,et al. Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. , 2012, Biochimica et biophysica acta.
[121] T. Whiteside,et al. The potential of tumor-derived exosomes for noninvasive cancer monitoring , 2015, Expert review of molecular diagnostics.
[122] Gema Moreno-Bueno,et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET , 2012, Nature Medicine.
[123] E. Campo,et al. Protein Kinase C θ Is Highly Expressed in Gastrointestinal Stromal Tumors But Not in Other Mesenchymal Neoplasias , 2004, Clinical Cancer Research.
[124] G. Blandino,et al. Glypican-1 exosomes: do they initiate a new era for early pancreatic cancer diagnosis? , 2016, Translational gastroenterology and hepatology.
[125] R. Simpson,et al. Proteomic profiling of exosomes: Current perspectives , 2008, Proteomics.
[126] Tohru Mochizuki,et al. Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line , 2010, PloS one.
[127] Ming-Tsang Wu,et al. Hypoxia-inducible Factor-1α is Associated with Risk of Aggressive Behavior and Tumor Angiogenesis in Gastrointestinal Stromal Tumor , 2005 .
[128] D. Baunsgaard,et al. A Comprehensive Evaluation of Nanoparticle Tracking Analysis (NanoSight) for Characterization of Proteinaceous Submicron Particles. , 2016, Journal of pharmaceutical sciences.
[129] D. Kang,et al. Isolation and Proteomic Analysis of Microvesicles and Exosomes from HT22 Cells and Primary Neurons. , 2017, Methods in molecular biology.
[130] L. Zitvogel,et al. Malignant effusions and immunogenic tumour-derived exosomes , 2002, The Lancet.
[131] Laurence Zitvogel,et al. Exosomes: composition, biogenesis and function , 2002, Nature Reviews Immunology.
[132] F. Wrba,et al. MAPKAP Kinase 2 Overexpression Influences Prognosis in Gastrointestinal Stromal Tumors and Associates with Copy Number Variations on Chromosome 1 and Expression of p38 MAP Kinase and ETV1 , 2012, Clinical Cancer Research.
[133] Deepa T. Patil,et al. Gastrointestinal stromal tumor: advances in diagnosis and management. , 2011, Archives of pathology & laboratory medicine.
[134] Z. Eroglu,et al. Beta-myosin heavy-chain mutations R403QLW, V606M, K615N and R663H in patients with hypertrophic cardiomyopathy. , 2014, Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology.
[135] D. Quail,et al. Microenvironmental regulation of tumor progression and metastasis , 2014 .
[136] G. Semenza. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. , 2012, Trends in pharmacological sciences.
[137] Ming-Tsang Wu,et al. Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor. , 2005, Japanese journal of clinical oncology.
[138] I. Espinosa,et al. The Utility of Discovered on Gastrointestinal Stromal Tumor 1 (DOG1) Antibody in Surgical Pathology—the GIST of It , 2010, Advances in anatomic pathology.
[139] L. Zitvogel,et al. Exosomes for immunotherapy of cancer. , 2003, Advances in experimental medicine and biology.
[140] Meral Günaldı,et al. Diagnostic and prognostic roles of DOG1 and Ki-67, in GIST patients with localized or advanced/metastatic disease. , 2014, International journal of clinical and experimental medicine.
[141] L. Trippa,et al. Prognostic role of circulating exosomal miRNAs in multiple myeloma. , 2017, Blood.
[142] C. Antonescu,et al. ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours , 2010, Nature.
[143] Fontana Simona,et al. Contribution of proteomics to understanding the role of tumor‐derived exosomes in cancer progression: State of the art and new perspectives , 2013 .
[144] Robert L Moritz,et al. Exosomes: proteomic insights and diagnostic potential , 2009, Expert review of proteomics.
[145] T. Rasmussen,et al. Exosomal proteins as prognostic biomarkers in non‐small cell lung cancer , 2016, Molecular oncology.
[146] M. Kesimer,et al. Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients. , 2012, Analytical biochemistry.
[147] B. Carr,et al. Company profile: NanoSight: delivering practical solutions for biological nanotechnology. , 2012, Nanomedicine.
[148] Gary K. Schwartz,et al. Tumour exosome integrins determine organotropic metastasis , 2015, Nature.
[149] Shreyaskumar R Patel. Managing progressive disease in patients with GIST: factors to consider besides acquired secondary tyrosine kinase inhibitor resistance. , 2012, Cancer treatment reviews.
[150] Xianyin Lai,et al. A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer , 2017, Cancer letters.
[151] Sybren L N Maas,et al. Tunable Resistive Pulse Sensing for the Characterization of Extracellular Vesicles. , 2017, Methods in molecular biology.
[152] G. Parmiani,et al. Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. , 2005, Gastroenterology.
[153] Z. Werb,et al. Coevolution of cancer and stromal cellular responses. , 2005, Cancer cell.
[154] D. Mukhopadhyay,et al. Exosomes and their role in the micro-/macro-environment: a comprehensive review , 2017, Journal of biomedical research.
[155] Andreas Krämer,et al. Causal analysis approaches in Ingenuity Pathway Analysis , 2013, Bioinform..